Search Results - "Brain research"

Neurotransmitter modulation by the gut microbiota by Strandwitz, Philip

“…[Display omitted] •The human microbiota has been linked to numerous components of health and disease.•Gut bacteria can influence diseases of the enteric and…”
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Macrophage activation and its role in repair and pathology after spinal cord injury by Gensel, John C, Zhang, Bei

“…Abstract The injured spinal cord does not heal properly. In contrast, tissue repair and functional recovery occur after skin or muscle injuries. The reason for…”
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Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage by Zhang, Zhuwei, Wu, Yu, Yuan, Shuai, Zhang, Peng, Zhang, Juyi, Li, Haiying, Li, Xiang, Shen, Haitao, Wang, Zhong, Chen, Gang

“…•The protein level of GPX4 in brain tissues was decreased at 24 h after ICH.•Over-expression of GPX4 can alleviate brain injury induced by ICH.•Blockade…”
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Gut microbiota in Parkinson disease in a northern German cohort by Hopfner, Franziska, Künstner, Axel, Müller, Stefanie H, Künzel, Sven, Zeuner, Kirsten E, Margraf, Nils G, Deuschl, Günther, Baines, John F, Kuhlenbäumer, Gregor

“…Highlights • Parkinson disease is associated with changes in the gut microbiota. • This study in agreement with most other studies suggests an increase in…”
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Factors influencing the blood-brain barrier permeability by Zhao, Yibin, Gan, Lin, Ren, Li, Lin, Yubo, Ma, Congcong, Lin, Xianming

“…•NVU proteins and components alter BBB permeability.•BBB transporters regulate BBB permeability.•Chemical mediators affect BBB permeability. The blood-brain…”
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The effect of curcumin on cognition in Alzheimer’s disease and healthy aging: A systematic review of pre-clinical and clinical studies by Voulgaropoulou, S.D., van Amelsvoort, T.A.M.J., Prickaerts, J., Vingerhoets, C.

“…•Animal studies show beneficial effects of curcumin on molecular and behavioral level.•Clinical studies are mixed regarding curcumin’s effects on cognitive…”
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The effects of acute exercise on cognitive performance: A meta-analysis by Chang, Y.K, Labban, J.D, Gapin, J.I, Etnier, J.L

“…Abstract There is a substantial body of literature related to the effects of a single session of exercise on cognitive performance. The premise underlying this…”
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Regulation of hippocampal synaptic plasticity by BDNF by Leal, Graciano, Afonso, Pedro M, Salazar, Ivan L, Duarte, Carlos B

“…Abstract The neurotrophin brain-derived neurotrophic factor (BDNF) has emerged as a major regulator of activity-dependent plasticity at excitatory synapses in…”
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bHLH transcription factors in neural development, disease, and reprogramming by Dennis, Daniel J., Han, Sisu, Schuurmans, Carol

“…•Review of the developmental and cellular functions of bHLH factors in the CNS.•Report of core regulatory mechanisms that govern bHLH gene expression and…”
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Four central questions about prediction in language processing by Huettig, Falk

“…Abstract The notion that prediction is a fundamental principle of human information processing has been en vogue over recent years. The investigation of…”
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Parkinson’s disease from the gut by Liddle, Rodger A.

“…A path for α-synuclein from the gut to the nervous system. Enteroendocrine cells (EECs) express α-synuclein and connect to α-synuclein-containing enteric…”
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Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by Zhang, Yan, Sun, Chao, Zhao, Chenxi, Hao, Jian, Zhang, Yiling, Fan, Baoyou, Li, Bo, Duan, Huiquan, Liu, Chang, Kong, Xiaohong, Wu, Ping, Yao, Xue, Feng, Shiqing

“…[Display omitted] •Ferroptosis, an iron dependent cell death pathway, contributed to secondary injury of SCI.•Ferroptosis inhibitor SRS 16-86 inhibits…”
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Retinal metabolism: A comparative look at energetics in the retina by Country, Michael W.

“…•Visual systems in vertebrates are energetically costly, especially in the dark.•Fish, birds, reptiles, and mammals each supply metabolites to retinas…”
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Coupling of neurogenesis and angiogenesis after ischemic stroke by Ruan, Linhui, Wang, Brian, ZhuGe, Qichuan, Jin, Kunlin

“…Abstract Stroke is a leading cause of mortality and severe long-term disability worldwide. Development of effective treatment or new therapeutic strategies for…”
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Nestin overexpression promotes the embryonic development of heart and brain through the regulation of cell proliferation by Liu, Jinkai, Ji, Xiaozhen, Li, Zhenlin, Zheng, Hua, Zheng, Wenhong, Jia, Junshuang, Shen, Hongfen, Zhang, Qianbing, An, Jing

“…Abstract Nestin, an intermediate filament protein, is a key regulator of various extracellular proteins that play important roles in cell growth and…”
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How microglia kill neurons by Brown, Guy C, Vilalta, Anna

“…Abstract Microglia are resident brain macrophages that become inflammatory activated in most brain pathologies. Microglia normally protect neurons, but may…”
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Astrocytes in heavy metal neurotoxicity and neurodegeneration by Li, Baoman, Xia, Maosheng, Zorec, Robert, Parpura, Vladimir, Verkhratsky, Alexei

“…•Astrocytes protect neurones against neurotoxicity induced by heavy metals.•Astrocytes are the main target for heavy metal neurotoxicity.•Heavy metals affect…”
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Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice by Yamawaki, Yosuke, Yoshioka, Norika, Nozaki, Kanako, Ito, Hikaru, Oda, Keisuke, Harada, Kana, Shirawachi, Satomi, Asano, Satoshi, Aizawa, Hidenori, Yamawaki, Shigeto, Kanematsu, Takashi, Akagi, Hiroyuki

“…•Lipopolysaccharide induced hippocampal microglia activation and depressive state.•Sodium butyrate reduced lipopolysaccharide-microglia activation and…”
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Prion-like domains as epigenetic Regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease by March, Zachary M, King, Oliver D, Shorter, James

“…Abstract Key challenges faced by all cells include how to spatiotemporally organize complex biochemistry and how to respond to environmental fluctuations. The…”
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The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury by Ge, Xintong, Li, Wenzhu, Huang, Shan, Yin, Zhenyu, Xu, Xin, Chen, Fanglian, Kong, Xiaodong, Wang, Haichen, Zhang, Jianning, Lei, Ping

“…•TBI leads to NLRs and AIM2 inflammasome-mediated pyroptosis in injured BMVECs.•Ac-YVAD-cmk inhibits NLRs and AIM2 inflammasome-mediated pyroptosis in injured…”
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