Search Results - "Brain Bank, The Netherlands"
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Correction to: Interplay between androgen and CXCR4 chemokine signaling in myelin repair
Published in Acta neuropathologica communications (15-07-2024)Get full text
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Perivascular phosphorylated TDP-43 inclusions are associated with Alzheimer's disease pathology and loss of CD146 and Aquaporin-4
Published in Brain pathology (Zurich, Switzerland) (09-09-2024)“…The majority of patients with Alzheimer's disease (AD) exhibit aggregates of Trans-active response DNA binding protein 43 (TDP-43) in their hippocampus, which…”
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Cellular localization of p-tau217 in brain and its association with p-tau217 plasma levels
Published in Acta neuropathologica communications (06-01-2022)“…Recent studies highlight phosphorylated tau (p-tau) at threonine tau 217 (p-tau217) as a new promising plasma biomarker for pathological changes implicated in…”
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Increased plasma and brain immunoglobulin A in Alzheimer's disease is lost in apolipoprotein E ε4 carriers
Published in Alzheimer's research & therapy (26-08-2022)“…Alzheimer's disease (AD) is foremost characterized by β-amyloid (Aβ)-extracellular plaques, tau-intraneuronal fibrillary tangles (NFT), and neuroinflammation,…”
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Plasma IAPP-Autoantibody Levels in Alzheimer's Disease Patients Are Affected by APOE4 Status
Published in International journal of molecular sciences (14-02-2023)“…Pancreas-derived islet amyloid polypeptide (IAPP) crosses the blood-brain barrier and co-deposits with amyloid beta (Aβ) in brains of type 2 diabetes (T2D) and…”
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The fluorescent ligand bTVBT2 reveals increased p-tau uptake by retinal microglia in Alzheimer’s disease patients and App NL−F/NL−F mice
Published in Alzheimer's research & therapy (2024)“…Background: Amyloid beta (Aβ) deposits and hyperphosphorylated tau (p-tau) accumulation have been identified in the retina of Alzheimer’s disease (AD) patients…”
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Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide
Published in Molecular brain (15-02-2023)“…The islet amyloid polypeptide (IAPP), a pancreas-produced peptide, has beneficial functions in its monomeric form. However, IAPP aggregates, related to type 2…”
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Interplay between androgen and CXCR4 chemokine signaling in myelin repair
Published in Acta neuropathologica communications (30-01-2024)“…In men, reduced levels of testosterone are associated with the prevalence and progression of multiple sclerosis (MS), a chronic and disabling demyelinating…”
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The Relationship between p-tau217, p-tau231, and p-tau205 in the Human Brain Is Affected by the Cellular Environment and Alzheimer's Disease Pathology
Published in Cells (Basel, Switzerland) (01-02-2024)“…The levels of p-tau217 and p-tau231 in cerebrospinal fluid (CSF) are associated with early amyloid beta (Aß) changes in the brain, while the CSF levels of…”
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Alpha-amylase 1A copy number variants and the association with memory performance and Alzheimer's dementia
Published in Alzheimer's research & therapy (21-11-2020)“…Previous studies have shown that copy number variation (CNV) in the alpha (α)-amylase gene (AMY1A) is associated with body mass index, insulin resistance, and…”
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Movement disorders are linked to TDP-43 burden in the substantia nigra of FTLD-TDP brain donors
Published in Acta neuropathologica communications (12-04-2023)“…Movement disorders (MD) have been linked to degeneration of the substantia nigra (SN) in Parkinson's disease and include bradykinesia, rigidity, and tremor…”
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