Search Results - "Brailsford, Alan"

Determination of anabolic steroids in dried blood using microsampling and gas chromatography-tandem mass spectrometry: Application to a testosterone gel administration study by Chang, William Chih-Wei, Cowan, David A., Walker, Christopher J., Wojek, Nick, Brailsford, Alan D.

“…•Nine anabolic steroids are separated within 6.4 min and are detectable at 50 fg.•VAMS dried blood exhibits good stability and better recovery over spotting…”
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Direct Monitoring of Exogenous γ‑Hydroxybutyric Acid in Body Fluids by NMR Spectroscopy by Palomino-Schätzlein, Martina, Wang, Yaoyao, Brailsford, Alan D, Parella, Teodor, Cowan, David A, Legido-Quigley, Cristina, Pérez-Trujillo, Míriam

“…γ-Hydroxybutyric acid (GHB) is a popular drug increasingly associated with cases of drug-facilitated sexual assault (DFSA). Currently, expanding procedures of…”
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Rapid Analysis of Anabolic Steroid Metabolites in Urine by Combining Field Asymmetric Waveform Ion Mobility Spectrometry with Liquid Chromatography and Mass Spectrometry by Arthur, Kayleigh L, Turner, Matthew A, Brailsford, Alan D, Kicman, Andrew T, Cowan, David A, Reynolds, James C, Creaser, Colin S

“…The combination of field asymmetric waveform ion mobility spectrometry with liquid chromatography–mass spectrometry (LC-FAIMS-MS) has been developed for the…”
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Blunted Endogenous Opioid Release Following an Oral Amphetamine Challenge in Pathological Gamblers by Mick, Inge, Myers, Jim, Ramos, Anna C, Stokes, Paul R A, Erritzoe, David, Colasanti, Alessandro, Gunn, Roger N, Rabiner, Eugenii A, Searle, Graham E, Waldman, Adam D, Parkin, Mark C, Brailsford, Alan D, Galduróz, José C F, Bowden-Jones, Henrietta, Clark, Luke, Nutt, David J, Lingford-Hughes, Anne R

“…Pathological gambling is a psychiatric disorder and the first recognized behavioral addiction, with similarities to substance use disorders but without the…”
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Response to Comment on “Direct Monitoring of Exogenous γ‑Hydroxybutyric Acid in Body Fluids by NMR Spectroscopy”: Several Issues to Consider When Quantifying γ‑Hydroxybutyric Acid in Biological Matrixes by Palomino-Schätzlein, Martina, Brailsford, Alan D, Parella, Teodor, Pérez-Trujillo, Míriam

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Pharmacokinetic Properties of γ-Hydroxybutyrate (GHB) in Whole Blood, Serum, and Urine by Brailsford, Alan D., Cowan, David A., Kicman, Andrew T.

“…Over the last 10-15 years, γ-hydroxybutyrate (GHB) and γ-butyrolactone have become increasingly popular "club drugs", but they have also gained attention as…”
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IRMS delta values (13C) of nandrolone and testosterone products available in the UK: Implications for anti‐doping by Brailsford, Alan D., Majidin, Wan Noor Mahirah, Wojek, Nick, Cowan, David A., Walker, Christopher

“…Anabolic androgenic steroids (AAS) are the most widely abused class of drugs by athletes and thus represent a significant problem to the anti‐doping community…”
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Acute toxicity and withdrawal syndromes related to gamma-hydroxybutyrate (GHB) and its analogues gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) by Wood, David M., Brailsford, Alan D., Dargan, Paul I.

“…Gamma‐hydroxybutyrate (GHB) has been used as a recreational drug since the 1990s and over the last few years there has been increasing use of its analogues…”
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Increases in Serum Growth Hormone Concentrations Associated with GHB Administration by Brailsford, Alan D, Bartlett, Christiaan, Kicman, Andrew T, Cowan, David A

“…The administration of gamma-hydroxybutyrate (GHB) has been reported to augment the increase in growth hormone (GH) secretion associated with the onset of…”
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Amphetamine induced endogenous opioid release in the human brain detected with [11C]carfentanil PET: replication in an independent cohort by Mick, Inge, Myers, Jim, Stokes, Paul R. A., Erritzoe, David, Colasanti, Alessandro, Bowden-Jones, Henrietta, Clark, Luke, Gunn, Roger N., Rabiner, Eugenii A., Searle, Graham E., Waldman, Adam D., Parkin, Mark C., Brailsford, Alan D., Nutt, David J., Lingford-Hughes, Anne R.

“…This study aimed to replicate a previous study which showed that endogenous opioid release, following an oral dose of amphetamine, can be detected in the…”
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Urinary γ-Hydroxybutyrate Concentrations in 1126 Female Subjects by Brailsford, Alan D., Cowan, David A., Kicman, Andrew T.

“…γ-Hydroxybutyrate (GHB) and its metabolic precursor γ-butyrolactone (GBL) are often implicated in cases of drug-facilitated sexual assault (DFSA), although…”
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A molecularly imprinted receptor for separation of testosterone and epitestosterone, based on a steroidal cross-linker by Gavrilović, Ivana, Mitchell, Karen, Brailsford, Alan D., Cowan, David A., Kicman, Andrew T., Ansell, Richard J.

“…► An imprinted polymer separates testosterone and epitestosterone in HPLC ( α = 3.6). ► 5α-Dihydrotestosterone, DHT, is used as template. ► Optimised polymer…”
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Retrospective drug detection in cases of drug-facilitated sexual assault: challenges and perspectives for the forensic toxicologist by Parkin, Mark C, Brailsford, Alan D

“…Reported incidences of drug-facilitated sexual assault (DFSA) are on the increase worldwide. These cases represent a particular challenge for the forensic…”
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Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals by Turton, Samuel, Myers, James FM, Mick, Inge, Colasanti, Alessandro, Venkataraman, Ashwin, Durant, Claire, Waldman, Adam, Brailsford, Alan, Parkin, Mark C, Dawe, Gemma, Rabiner, Eugenii A, Gunn, Roger N, Lightman, Stafford L, Nutt, David J, Lingford-Hughes, Anne

“…Addiction has been proposed as a ‘reward deficient’ state, which is compensated for with substance use. There is growing evidence of dysregulation in the…”
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Pharmacokinetic Properties of Delta g-Hydroxybutyrate (GHB) in Whole Blood, Serum, and Urine by Brailsford, Alan D, Cowan, David A, Kicman, Andrew T

“…Over the last 10-15 years, Delta *g-hydroxybutyrate (GHB) and Delta *g-butyrolactone have become increasingly popular 'club drugs', but they have also gained…”
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Identification and characterization of the surface-layer protein of Clostridium tetani by Qazi, Omar, Brailsford, Alan, Wright, Anne, Faraar, Jeremy, Campbell, Jim, Fairweather, Neil

“…Many bacterial species produce a paracrystalline layer, the surface layer, which completely surrounds the exterior of the cell. In some bacteria, the surface…”
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OR-71: blunted endogenous opioid release following an oral amphetamine challenge in pathological gamblers by Mick, Inge, Myers, Jim, Ramos, Anna C, Stokes, Paul Ra, Erritzoe, David, Colasanti, Alessandro, Gunn, Roger N, Rabiner, Eugenii A, Searle, Graham E, Waldman, Adam D, Parkin, Mark C, Brailsford, Alan D, Galduroz, Jose Cf, Bowden-Jones, Henrietta, Clark, Luke, Nutt, David J, Lingford-Hughes, Anne R

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A first-principles model of the zirconia oxygen sensor by Brailsford, A.D., Yussouff, M., Logothetis, E.M.

“…Zirconia oxygen sensors are used extensively to monitor the air-to-fuel ratio of internal combustion engines. The basic physical and chemical processes…”
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A first principles model of metal oxide gas sensors for measuring combustibles by Brailsford, A.D., Yussouff, M., Logothetis, E.M.

“…A first principles model is described for the operation of electrochemical type sensors designed to measure combustibles in air. It is based on the general…”
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Steady state model of electrochemical gas sensors with multiple reactions by Brailsford, A.D., Yussouff, M., Logothetis, E.M.

“…We present an extension of the first-principles model for the steady state response of electrochemical (e.g. zirconia) gas sensors. In earlier work, it was…”
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