Search Results - "Braicu, Ioana Elena"

Methylation status of TUSC3 is a prognostic factor in ovarian cancer by Pils, Dietmar, Horak, Peter, Vanhara, Petr, Anees, Mariam, Petz, Michaela, Alfanz, Angela, Gugerell, Alfred, Wittinger, Michael, Gleiss, Andreas, Auner, Veronika, Tong, Dan, Zeillinger, Robert, Braicu, Elena‐Ioana, Sehouli, Jalid, Krainer, Michael

“…BACKGROUND. Current prognostic information in ovarian cancer is based on tumor stage, tumor grade, and postoperative tumor size. Reliable molecular prognostic…”
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Primary versus interval debulking surgery in advanced ovarian cancer: results from a systematic single-center analysis by Sehouli, Jalid, Savvatis, Konstantinos, Braicu, Elena-Ioana, Schmidt, Sven-Christian, Lichtenegger, Werner, Fotopoulou, Christina

“…To evaluate the difference in operative and clinical outcome for patients with primary advanced ovarian cancer (AOC) after optimal primary debulking surgery…”
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Patients' subjective assessment as a decisive predictor of malignancy in pelvic masses: results of a multicentric, prospective pelvic mass study by Koch, Elisa, Torsten, Uwe, Mecke, Herbert, Richter, Rolf, Hellmeyer, Lars, Nohe, Gerhard, Müller, Bodo, Boeneß-Zaloum, Janine, Ames, Kerstin, Chen, Frank, Beteta, Carmen, Hasenbein, Kati, Pirmorady, Adak, Zimmermann, Mathias, Dimitrova, Desislava, Tauber, Rudolf, Sehouli, Jalid, Knieper, Catherine Linn, Ioana Braicu, Elena

“…The prognosis for ovarian cancer patients remains poor. A key to maximizing survival rates is early detection and treatment. This requires an accurate…”
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Impact of ascites on the perioperative course of patients with advanced ovarian cancer undergoing extensive cytoreduction: results of a study on 119 patients by Feldheiser, Aarne, Braicu, Elena-Ioana, Bonomo, Tommaso, Walther, Anne, Kaufner, Lutz, Pietzner, Klaus, Spies, Claudia, Sehouli, Jalid, Fotopoulou, Christina

“…Cytoreductive surgery for epithelial ovarian cancer (EOC) is the cornerstone of multimodal therapy and considered as a high-risk surgery because of extensive…”
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Aldehyde dehydrogenase 1/epidermal growth factor receptor coexpression is characteristic of a highly aggressive, poor-prognosis subgroup of high-grade serous ovarian carcinoma by Liebscher, Catarina Alisa, Prinzler, Judith, Sinn, Bruno Valentin, MD, Budczies, Jan, PhD, Denkert, Carsten, MD, Noske, Aurelia, MD, Sehouli, Jalid, MD, Braicu, Elena Ioana, MD, Dietel, Manfred, MD, Darb-Esfahani, Silvia, MD

“…Summary In models of triple-negative breast cancer (TNBC), it has recently been shown that the epidermal growth factor receptor (EGFR) pathway is up-regulated…”
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Sentinel Node Mapping in Cervical and Endometrial Cancer: Indocyanine Green Versus Other Conventional Dyes—A Meta-Analysis by Ruscito, Ilary, Gasparri, Maria Luisa, Braicu, Elena Ioana, Bellati, Filippo, Raio, Luigi, Sehouli, Jalid, Mueller, Michael D., Panici, Pierluigi Benedetti, Papadia, Andrea

“…Background Historically, blue dyes, 99 Tc or a combination of the two tracers have been used for sentinel lymph node (SLN) mapping in cervical and endometrial…”
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Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas by Hilvo, Mika, de Santiago, Ines, Gopalacharyulu, Peddinti, Schmitt, Wolfgang D, Budczies, Jan, Kuhberg, Marc, Dietel, Manfred, Aittokallio, Tero, Markowetz, Florian, Denkert, Carsten, Sehouli, Jalid, Frezza, Christian, Darb-Esfahani, Silvia, Braicu, Elena Ioana

“…Ovarian cancer is a heterogeneous disease of low prevalence, but poor survival. Early diagnosis is critical for survival, but it is often challenging because…”
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Immunoglobulin G Subclass-Specific Glycosylation Changes in Primary Epithelial Ovarian Cancer by Wieczorek, Marta, Braicu, Elena Ioana, Oliveira-Ferrer, Leticia, Sehouli, Jahid, Blanchard, Véronique

“…Epithelial ovarian cancer (EOC) was previously shown to be associated with glycosylation changes of total serum and total IgG proteins. However, as a majority…”
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ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer by Su, Pingping, Mao, Xiaodan, Ma, Jincheng, Huang, Lixiang, Yu, Lirui, Tang, Shuting, Zhuang, Mingzhi, Lu, Zhonglei, Osafo, Kelvin Stefan, Ren, Yuan, Wang, Xinrui, Lin, Xite, Huang, Leyi, Huang, Xiaoli, Braicu, Elena Ioana, Sehouli, Jalid, Sun, Pengming

“…Tumor cells can resist chemotherapy-induced pyroptosis through glycolytic reprogramming. Estrogen-related receptor alpha (ERRα) is a central regulator of…”
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HE4 as a serum biomarker for the diagnosis of pelvic masses: a prospective, multicenter study in 965 patients by Braicu, Elena Ioana, Krause, Catherine Linn, Torsten, Uwe, Mecke, Herbert, Richter, Rolf, Hellmeyer, Lars, Lanowska, Malgorzata, Müller, Bodo, Koch, Elisa, Boenness-Zaloum, Janine, Ames, Kerstin, Chekerov, Radoslav, Hasenbein, Kati, Zimmermann, Mathias, Mangler, Mandy, Chen, Frank, Tauber, Rudolf, Sehouli, Jalid

“…Abstract Background To evaluate the diagnostic value of adding human epididymis protein 4 (HE4), cancer antigen 125 (CA125) and risk of malignancy algorithm…”
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Increased expression of IDO1 is associated with improved survival and increased number of TILs in patients with high-grade serous ovarian cancer by Hoffmann, Inga, Dragomir, Mihnea P., Monjé, Nanna, Keunecke, Carlotta, Kunze, Catarina Alisa, Schallenberg, Simon, Marchenko, Sofya, Schmitt, Wolfgang D., Kulbe, Hagen, Sehouli, Jalid, Braicu, Ioana Elena, Jank, Paul, Denkert, Carsten, Darb-Esfahani, Silvia, Horst, David, Sinn, Bruno V., Sers, Christine, Bischoff, Philip, Taube, Eliane T.

“…The enzyme indoleamine 2,3-dioxygenase 1 (IDO1) plays a crucial role in regulating the immune system's response to tumors, but its exact role in cancer,…”
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Prognostic significance of Ki-67 levels and hormone receptor expression in low-grade serous ovarian carcinoma: an investigation of the Tumor Bank Ovarian Cancer Network by Sehouli, Jalid, Braicu, Elena Ioana, Richter, Rolf, Denkert, Carsten, Jank, Paul, Jurmeister, Philipp Sebastian, Kunze, Catarina Alisa, Budczies, Jan, Darb-Esfahani, Sylvia, Schmitt, Wolfgang Daniel, Traut, Alexander, Grabowski, Jacek, Taube, Eliane Tabea, Plett, Helmut

“…Low-grade serous ovarian carcinoma (LGSOC) has recently come up as a distinct rare entity of epithelial ovarian cancer. Predictive and prognostic markers are…”
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Polycomb Protein BMI-1 as a Potential Therapeutic Target in Mucinous Ovarian Cancer by Abobaker, Salem, Kulbe, Hagen, Taube, Eliane T, Darb-Esfahani, Silvia, Richter, Rolf, Denkert, Carsten, Jank, Paul, Sehouli, Jalid, Braicu, Elena Ioana

“…Mucinous ovarian carcinoma (mOC) is a rare subtype with distinct clinical characteristics and biological behavior that differentiate them from other epithelial…”
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Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer by Heitz, Florian, Lakis, Sotirios, Harter, Philipp, Heikaus, Sebastian, Sehouli, Jalid, Talwar, Jatin, Menon, Roopika, Ataseven, Beyhan, Bertrand, Miriam, Schneider, Stephanie, Mariotti, Erika, Bommert, Mareike, Müller, Judith N, Prader, Sonia, Leenders, Frauke, Hengsbach, Alexandra, Gloeckner, Christian, Braicu, Elena Ioana, Heukamp, Lukas C, du Bois, Andreas, Heuckmann, Johannes M

“…The present prospective study aimed at determining the impact of cell-free tumor DNA (ct-DNA), CA125 and HE4 from blood and ascites for quantification of tumor…”
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Potential role of the HOXD8 transcription factor in cisplatin resistance and tumour metastasis in advanced epithelial ovarian cancer by Sun, PengMing, Song, YiYi, Liu, DaBin, Liu, GuiFen, Mao, XiaoDan, Dong, BinHua, Braicu, Elena Ioana, Sehouli, Jalid

“…Few studies have examined the potential transcription factor (TF) simultaneously associated with cisplatin resistance and metastasis in ovarian cancer. To…”
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Circulating tumor cells: potential markers of minimal residual disease in ovarian cancer? a study of the OVCAD consortium by Obermayr, Eva, Bednarz-Knoll, Natalia, Orsetti, Beatrice, Weier, Heinz-Ulrich, Lambrechts, Sandrina, Castillo-Tong, Dan Cacsire, Reinthaller, Alexander, Braicu, Elena Ioana, Mahner, Sven, Sehouli, Jalid, Vergote, Ignace, Theillet, Charles, Zeillinger, Robert, Brandt, Burkhard

“…In 75% of ovarian cancer patients the tumor mass is completely eradicated by established surgical and cytotoxic treatment; however, the majority of the tumors…”
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A Risk Model for Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer: An Evidence-Based Proposal for Patient Selection by Tian, Wen-Juan, Chi, Dennis S., Sehouli, Jalid, Tropé, Claes G., Jiang, Rong, Ayhan, Ali, Cormio, Gennaro, Xing, Yan, Breitbach, Georg-Peter, Braicu, Elena Ioana, Rabbitt, Catherine A., Oksefjell, Halldis, Fotopoulou, Christina, Meerpohl, Hans-Gerd, du Bois, Andreas, Berek, Jonathan S., Zang, Rong-Yu, Harter, Philipp

“…Background To develop a risk model for predicting complete secondary cytoreductive surgery (SCR) in patients with recurrent ovarian cancer. Methods Individual…”
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Primary versus secondary cytoreduction for epithelial ovarian cancer: A paired analysis of tumour pattern and surgical outcome by Braicu, Elena-Ioana, Sehouli, Jalid, Richter, Rolf, Pietzner, Klaus, Lichtenegger, Werner, Fotopoulou, Christina

“…Abstract Objective Recurrence rates of Epithelial Ovarian Cancer (EOC) remain high. Aim of the present study was to compare tumour pattern and surgical outcome…”
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Chondroitin Sulfate Disaccharides, a Serum Marker for Primary Serous Epithelial Ovarian Cancer by Biskup, Karina, Stellmach, Caroline, Braicu, Elena Ioana, Sehouli, Jalid, Blanchard, Véronique

“…Glycosaminoglycans are long polysaccharidic chains, which are mostly present in connective tissues. Modified GAG expression in tissues surrounding malignant…”
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High EVI1 and PARP1 expression as favourable prognostic markers in high-grade serous ovarian carcinoma by Jank, Paul, Leichsenring, Jonas, Kolb, Svenja, Hoffmann, Inga, Bischoff, Philip, Kunze, Catarina Alisa, Dragomir, Mihnea P, Gleitsmann, Moritz, Jesinghaus, Moritz, Schmitt, Wolfgang D, Kulbe, Hagen, Sers, Christine, Stenzinger, Albrecht, Sehouli, Jalid, Braicu, Ioana Elena, Westhoff, Christina, Horst, David, Denkert, Carsten, Gröschel, Stefan, Taube, Eliane T

“…Mechanisms of development and progression of high-grade serous ovarian cancer (HGSOC) are poorly understood. EVI1 and PARP1, part of TGF-ß pathway, are…”
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