Search Results - "Brahmandam, M"

CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies by Ogino, S, Cantor, M, Kawasaki, T, Brahmandam, M, Kirkner, G J, Weisenberger, D J, Campan, M, Laird, P W, Loda, M, Fuchs, C S

“…Background: The concept of CpG island methylator phenotype (CIMP) is not universally accepted. Even if specific clinicopathological features have been…”
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A novel Bcl-2/Bcl-XL/Bcl-W inhibitor ABT-737 as therapy in multiple myeloma by CHAUHAN, D, VELANKAR, M, ANDERSON, K. C, BRAHMANDAM, M, HIDESHIMA, T, PODAR, K, RICHARDSON, P, SCHLOSSMAN, R, GHOBRIAL, I, RAJE, N, MUNSHI, N

“…Bcl-2 or Bcl-X(L) confers resistance to chemotherapy in multiple myeloma (MM). Here we characterized the effects of ABT-737, a potent small-molecule inhibitor…”
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Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target by Chauhan, Dharminder, Singh, Ajita V., Brahmandam, Mohan, Carrasco, Ruben, Bandi, Madhavi, Hideshima, Teru, Bianchi, Giada, Podar, Klaus, Tai, Yu-Tzu, Mitsiades, Constantine, Raje, Noopur, Jaye, David L., Kumar, Shaji K., Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.

“…Multiple myeloma (MM) remains incurable despite novel therapies, suggesting the need for further identification of factors mediating tumorigenesis and drug…”
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Sensitive Sequencing Method for KRAS Mutation Detection by Pyrosequencing by Ogino, Shuji, Kawasaki, Takako, Brahmandam, Mohan, Yan, Liying, Cantor, Mami, Namgyal, Chungdak, Mino-Kenudson, Mari, Lauwers, Gregory Y., Loda, Massimo, Fuchs, Charles S.

“…Both benign and malignant tumors represent heterogenous tissue containing tumor cells and non-neoplastic mesenchymal and inflammatory cells. To detect a…”
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Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component by Ogino, Shuji, Brahmandam, Mohan, Cantor, Mami, Namgyal, Chungdak, Kawasaki, Takako, Kirkner, Gregory, Meyerhardt, Jeffrey A, Loda, Massimo, Fuchs, Charles S

“…Signet ring cell carcinoma and mucinous carcinoma are distinct subtypes of colorectal adenocarcinoma. The morphologic and molecular spectra of colorectal…”
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Molecular Alterations in Tumors and Response to Combination Chemotherapy with Gefitinib for Advanced Colorectal Cancer by OGINO, Shuji, MEYERHARDT, Jeffrey A, KULKE, Matthew H, RYAN, David P, LODA, Massimo, FUCHS, Charles S, CANTOR, Mami, BRAHMANDAM, Mohan, DARK, Jeffrey W, NAMGYAL, Chungdak, KAWASAKI, Takako, KINSELLA, Kate, MICHELINI, Ann L, ENZIRIGER, Peter C

“…Purpose: Recently, activating mutations of the epidermal growth factor receptor ( EGFR ) gene were discovered in non–small cell lung cancers sensitive to…”
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Combined Analysis of COX-2 and p53 Expressions Reveals Synergistic Inverse Correlations with Microsatellite Instability and CpG Island Methylator Phenotype in Colorectal Cancer by Ogino, Shuji, Brahmandam, Mohan, Kawasaki, Takako, Kirkner, Gregory J., Loda, Massimo, Fuchs, Charles S.

“…Cyclooxygenase-2 (COX-2) overexpression and mutations of p53 (a known COX-2 regulator) are inversely associated with microsatellite instability—high (MSI-H)…”
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A novel Bcl-2 Bcl-X Bcl-w inhibitor ABT-737 as therapy in multiple myeloma by Chauhan, D, Velankar, M, Brahmandam, M, Hideshima, T, Podar, K, Richardson, P, Schlossman, R, Ghobrial, I, Raje, N, Munshi, N, Anderson, K C

“…Bcl-2 or Bcl-X(L) confers resistance to chemotherapy in multiple myeloma (MM). Here we characterized the effects of ABT-737, a potent small-molecule inhibitor…”
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A novel Bcl-2/Bcl-X sub(L)/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma by Chauhan, D, Velankar, M, Brahmandam, M, Hideshima, T, Podar, K, Richardson, P, Schlossman, R, Ghobrial, I, Raje, N, Munshi, N, Anderson, K C

“…Bcl-2 or Bcl-X sub(L) confers resistance to chemotherapy in multiple myeloma (MM). Here we characterized the effects of ABT-737, a potent small-molecule…”
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A novel Bcl-2/Bcl-X sub(L)/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma by Chauhan, D, Velankar, M, Brahmandam, M, Hideshima, T, Podar, K, Richardson, P, Schlossman, R, Ghobrial, I, Raje, N, Munshi, N, Anderson, K C

“…Bcl-2 or Bcl-X sub(L) confers resistance to chemotherapy in multiple myeloma (MM). Here we characterized the effects of ABT-737, a potent small-molecule…”
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Iliac branch endoprosthesis for repair of a common iliac artery aneurysm in Loeys-Dietz syndrome type 3 by Brahmandam, Anand, Guzman, Raul J., Nassiri, Naiem

“…The commercial availability of the iliac branch endoprosthesis (IBE) has permitted endovascular repair of iliac artery aneurysms with the preservation of…”
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USP2a is an oncogenic isopeptidase and a potential target in prostate cancer by Priolo, C., Tang, D., Brahmandam, M., Benassi, B., Sicinska, E., Ogino, S., Farsetti, A., Porrello, A., Febbo, P. G., Zimmermann, J., Loda, M. F.

“…Abstract only 14522 Background: De-ubiquitinating enzymes (isopeptidases) remove ubiquitin side chains prior to degradation by the proteosome thus stabilizing…”
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Endovascular treatment of renal vein thrombosis in a young patient with lung transplant by Pinto Rodriguez, Paula, Brahmandam, Anand, Turner, Jeffrey, Lee, Alfred, Ochoa Chaar, Cassius Iyad

“…Spontaneous renal vein thrombosis is a rare entity. A 28-year-old woman with a history of a double-lung transplant was admitted with flank pain and found to…”
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The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access by Brahmandam, Anand, Huttler, Joshua, Bellamkonda, Kirthi, Setia, Ocean, Cardella, Jonathan A., Stewart, William, Guzman, Raul J., Ochoa Chaar, Cassius Iyad

“…Common femoral artery (CFA) access is commonly used for endovascular interventions. Access site complications contribute to significant morbidity and…”
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EphB4 monomer inhibits chronic graft vasculopathy in an aortic transplant model by Langford, John T., Gonzalez, Luis, Taniguchi, Ryosuke, Brahmandam, Anand, Zhang, Weichang, Dardik, Alan

“…T cells and macrophages play an important role in the formation of allograft vasculopathy, which is the predominant form of chronic rejection in cardiac…”
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A narrative review on the application of high-intensity focused ultrasound for the treatment of occlusive and thrombotic arterial disease by Brahmandam, Anand, Chan, Shin Mei, Dardik, Alan, Nassiri, Naiem, Aboian, Edouard

“…High-intensity focused ultrasound (HIFU) is a noninvasive therapeutic modality with a variety of applications. It is approved for the treatment of essential…”
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Aortic remodeling and competitive flow after surgical treatment of aortic dissection by Chan, Shin Mei, Brahmandam, Anand, Cardella, Jonathan A., Elefteriades, John, Setaro, John F., Mangi, Abeel A., Ochoa Chaar, Cassius Iyad

“…Aortic remodeling after dissection is poorly understood and remains a focus of current research. In the present report, we have described the cases of two…”
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Mechanochemical and surgical ablation of an anomalous upper extremity marginal vein in CLOVES syndrome identifies PIK3CA as the culprit gene mutation by Lim, Young, Fereydooni, Arash, Brahmandam, Anand, Dardik, Alan, Choate, Keith, Nassiri, Naiem

“…Anomalous marginal veins of the trunk or extremities are congenitally incompetent entities found in association with phosphatidylinositol 4,5-bisphosphate…”
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Heterozygous signal transducer and activator of transcription 3 mutations in hyper-IgE syndrome result in altered B-cell maturation by Meyer-Bahlburg, Almut, MD, Renner, Ellen D., MD, Rylaarsdam, Stacey, AS, Reichenbach, Janine, MD, Schimke, Lena F., MD, Marks, Amy, DO, Tcheurekdjian, Haig, MD, Hostoffer, Robert, DO, Brahmandam, Archana, MS, Torgerson, Troy R., MD, PhD, Belohradsky, Bernd H., MD, Rawlings, David J., MD, Ochs, Hans D., MD

“…Despite normal B-cell counts, BAFF-R expression levels were significantly lower in patients with HIES (Fig 2, A). Because plasma BAFF levels can affect BAFF-R…”
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Is Pulmonary Embolism Predictable in Patients With Deep Vein Thrombosis? by Huynh, Nancy, BS, Fares, Wassim, MD, MPH, Brownson, Kirstyn, MD, Brahmandam, Anand, MD, Lee, Alfred I., MD, PhD, Dardik, Alan, MD, PhD, Sarac, Timur, MD, Ochoa Chaar, Cassius Iyad

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