Search Results - "Brahim, Jaime S."
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Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction
Published in Proceedings of the National Academy of Sciences - PNAS (20-11-2012)“…No conventional therapy exists for salivary hypofunction in surviving head and neck cancer patients with Radiation Therapy Oncology Group late grade 2–3…”
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Daily parathyroid hormone 1-34 replacement therapy for hypoparathyroidism induces marked changes in bone turnover and structure
Published in Journal of bone and mineral research (01-08-2012)“…Parathyroid hormone (PTH) has variable actions on bone. Chronically increased PTH is catabolic and leads to osteoporosis; yet intermittent administration is…”
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Evaluation of Biologic End Points and Pharmacokinetics in Patients With Metastatic Breast Cancer After Treatment With Erlotinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
Published in Journal of clinical oncology (01-08-2004)“…To evaluate changes in epidermal growth factor receptor (EGFR) phosphorylation and its downstream signaling in tumor and surrogate tissue biopsies in patients…”
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Oral findings in 58 adults with tuberous sclerosis complex
Published in Journal of the American Academy of Dermatology (01-05-2007)“…Background Gingival fibromas and dental pitting are among the diagnostic criteria for tuberous sclerosis complex (TSC). Objective Our goal was to document the…”
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Nitric Oxide is Negatively Correlated to Pain during Acute Inflammation
Published in Molecular pain (15-09-2010)“…Background: The role that nitric oxide (NO) plays in modulating pain in the periphery is unclear. We show here, the results of two independent clinical studies…”
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Skin cancers, blindness, and anterior tongue mass in African brothers
Published in Journal of the American Academy of Dermatology (01-11-2008)Get full text
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Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction
Published in Biochimica et biophysica acta (01-08-2006)“…The treatment of most patients with head and neck cancer includes ionizing radiation (IR). Salivary glands in the IR field suffer significant and irreversible…”
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Phase I Trial of the Cyclin-Dependent Kinase Inhibitor Flavopiridol in Combination with Docetaxel in Patients with Metastatic Breast Cancer
Published in Clinical cancer research (01-08-2004)“…Purpose: The purpose of this study was to determine the toxicities and characterize the pharmacokinetics of docetaxel and flavopiridol in patients with…”
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Aquaporin-1 gene transfer to correct radiation-induced salivary hypofunction
Published in Handbook of experimental pharmacology (2009)“…Irradiation damage to salivary glands is a common iatrogenic consequence of treatment for head and neck cancers. The subsequent lack of saliva production leads…”
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Kinin B1 Receptors Contributes to Acute Pain following Minor Surgery in Humans
Published in Molecular pain (13-02-2010)“…Background: Kinins play an important role in regulation of pain and hyperalgesia after tissue injury and inflammation by activating two types of…”
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In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model
Published in Clinical pharmacology and therapeutics (01-07-2002)“…Objective Prostanoids formed by cyclooxygenase play an important role in pain and the induction of inflammation. It is generally believed that COX‐1 is…”
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Lymphomatoid Granulomatosis With Involvement of the Hard Palate: A Case Report
Published in Journal of oral and maxillofacial surgery (01-10-2008)Get full text
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Transcriptional events in a clinical model of oral mucosal tissue injury and repair
Published in Wound repair and regeneration (01-01-2005)“…Tissue injury in the oral mucosa activates a cascade of transcriptional events important during the healing process that are not yet clearly defined. To…”
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Acetaminophen selectively suppresses peripheral prostaglandin E2 release and increases COX-2 gene expression in a clinical model of acute inflammation
Published in Pain (Amsterdam) (01-06-2007)“…Acetaminophen is widely used for pain management as an alternative to NSAIDs and selective COX-2 inhibitors, but its action at a molecular level is still…”
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Clinical Vignette: PTH(1–34) Replacement Therapy in a Child With Hypoparathyroidism Caused by a Sporadic Calcium Receptor Mutation
Published in Journal of bone and mineral research (01-05-2009)“…Autosomal dominant hypocalcemia (ADH) is an inherited form of hypoparathyroidism caused by activating mutations in the calcium‐sensing receptor (CaR)…”
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PTH(1-34) Replacement Therapy in a Child With Hypoparathyroidism Caused by a Sporadic Calcium Receptor Mutation
Published in Journal of bone and mineral research (01-05-2009)“…Autosomal dominant hypocalcemia (ADH) is an inherited form of hypoparathyroidism caused by activating mutations in the calcium-sensing receptor (CaR)…”
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The Differential Effects of Bupivacaine and Lidocaine on Prostaglandin E2 Release, Cyclooxygenase Gene Expression and Pain in a Clinical Pain Model
Published in Anesthesia and analgesia (01-01-2008)“…In addition to blocking nociceptive input from surgical sites, long-acting local anesthetics might directly modulate inflammation. In the present study, we…”
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Kinin B 1 Receptors Contributes to Acute Pain following Minor Surgery in Humans
Published in Molecular pain (13-02-2010)“…Background: Kinins play an important role in regulation of pain and hyperalgesia after tissue injury and inflammation by activating two types of…”
Get full text
Journal Article