Search Results - "Braghiroli, Maria Ignez Freitas Melro"

Safety and efficacy of cytotoxic chemotherapy in hepatocellular carcinoma after first-line treatment with sorafenib by da Fonseca, Leonardo Gomes, Marta, Guilherme Nader, Braghiroli, Maria Ignez Freitas Melro, Chagas, Aline Lopes, Carrilho, Flair Jose, Hoff, Paulo Marcelo, Sabbaga, Jorge

“…Before the targeted therapies era, cytotoxic chemotherapy (CCT) was an option for advanced hepatocellular carcinoma (HCC), even with the lack of supporting…”
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Advancements and challenges in gastric cancer: epidemiology, biomarkers, and therapeutic strategies by Nishimuni, Marina, Claro, Laura Carolina Lopez, Braghiroli, Maria Ignez Freitas Melro

“…Abstract Gastric cancer is the fifth most common cause of cancer-related deaths globally, with a decreasing but still high number of cases. Although there have…”
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Is There a Role for Locoregional Therapies for Non-colorectal Gastrointestinal Malignancies? by Fonseca, Gilton Marques, Braghiroli, Maria Ignez Freitas Melro, Pirola Kruger, Jaime Arthur, Coelho, Fabricio Ferreira, Herman, Paulo

“…The liver is the most common site of metastases from solid gastrointestinal tract tumors. Over the past few decades, the role of locoregional therapies,…”
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Nivolumab (NIVO) plus ipilimumab (IPI) or NIVO plus chemotherapy (chemo) versus chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): First results of the CheckMate 648 study by Chau, Ian, Doki, Yuichiro, Ajani, Jaffer A., Xu, Jianming, Wyrwicz, Lucjan, Motoyama, Satoru, Ogata, Takashi, Kawakami, Hisato, Hsu, Chih-Hung, Adenis, Antoine, El Hajbi, Farid, Di Bartolomeo, Maria, Braghiroli, Maria Ignez Freitas Melro, Holtved, Eva, Xynos, Ioannis, Liu, Xuan, Lei, Ming, Kondo, Kaoru, Kato, Ken, Kitagawa, Yuko

“…Abstract only LBA4001 Background: NIVO demonstrated superior overall survival (OS) vs chemo in previously treated patients (pts) with ESCC (ATTRACTION-3). We…”
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Unveiling the Landscape of Brazilian Clinical Oncologists: Challenges, Diversity, and Quality Care by Bezerra, Sarah Mendes, Madi, Marisa Riscalla, Chaves, Aline Lauda Freitas, Melro-Braghiroli, Maria Ignez Freitas, Hoff, Paulo Marcelo Gehm, Ferreira, Carlos Gil, Bonanno, Lucas Pondaco, Leite, Gustavo Andrade Pimenta

“…Abstract Cancer remains a significant public health challenge in Brazil, with an estimated 704 thousand new cases annually. Clinical oncology, a pivotal…”
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BRAZILIAN SOCIETY OF HEPATOLOGY UPDATED RECOMMENDATIONS FOR DIAGNOSIS AND TREATMENT OF HEPATOCELLULAR CARCINOMA by Chagas, Aline Lopes, Mattos, Angelo Alves de, Carrilho, Flair José, Bittencourt, Paulo Lisboa, Vezozzo, Denise Cerqueira Paranaguá, Horvat, Natally, Rocha, Manoel de Souza, Alves, Venâncio Avancini Ferreira, Coral, Gabriela Perdomo, Alvares-DA-Silva, Mario Reis, Barros, Fabio Marinho do Rego, Menezes, Marcos Roberto, Monsignore, Lucas Moretti, Coelho, Fabricio Ferreira, Silva, Renato Ferreira da, Silva, Rita de Cássia Martins Alves, Boin, Ilka de Fatima Santana Ferreira, D Albuquerque, Luiz Augusto Carneiro, Garcia, José Huygens Parente, Felga, Guilherme Eduardo Gonçalves, Moreira, Airton Mota, Braghiroli, Maria Ignez Freitas Melro, Hoff, Paulo Marcelo Gehm, Mello, Vivianne Barretto de, Dottori, Mariana Fonseca, Branco, Tiago Pugliese, Schiavon, Leonardo de Lucca, Costa, Thaisa de Fátima Almeida

“…Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. The Brazilian Society of Hepatology (SBH) published in 2015…”
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Is There a Role for Locoregional Therapies for Non-colorectal Gastrointestinal Malignancies? by Fonseca, Gilton Marques, Braghiroli, Maria Ignez Freitas Melro, Pirola Kruger, Jaime Arthur, Coelho, Fabricio Ferreira, Herman, Paulo

“…The liver is the most common site of metastases from solid gastrointestinal tract tumors. Over the past few decades, the role of locoregional therapies,…”
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Nivolumab (NIVO) plus chemotherapy (chemo) or ipilimumab (IPI) vs chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): 29-month (mo) follow-up from CheckMate 648 by Kato, Ken, Ajani, Jaffer A., Doki, Yuichiro, Xu, Jianming, Wyrwicz, Lucjan, Motoyama, Satoru, Ogata, Takashi, Kawakami, Hisato, Hsu, Chih-Hung, Adenis, Antoine, El Hajbi, Farid, Di Bartolomeo, Maria, Braghiroli, Maria Ignez Freitas Melro, Holtved, Eva, Blum Murphy, Mariela A., Patel, Apurva, Hu, Nan, Matsumura, Yasuhiro, Chau, Ian, Kitagawa, Yuko

“…290 Background: NIVO + chemo and NIVO + IPI demonstrated superior overall survival (OS) vs chemo in CheckMate 648 (NCT03143153), leading to approvals in the…”
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Does cytotoxic chemotherapy (CT) have a role in palliative treatment of hepatocellular carcinoma (HCC)? by Nader Marta, Guilherme, Fonseca, Leonardo Gomes da, Braghiroli, Maria Ignez Freitas Melro, Hoff, Paulo Marcelo, Sabbaga, Jorge

“…Abstract only…”
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Nivolumab (NIVO) plus chemotherapy (chemo) or ipilimumab (IPI) versus chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): Expanded efficacy and safety analyses from CheckMate 648 by Chau, Ian, Ajani, Jaffer A., Doki, Yuichiro, Xu, Jianming, Wyrwicz, Lucjan, Motoyama, Satoru, Ogata, Takashi, Kawakami, Hisato, Hsu, Chih-Hung, Adenis, Antoine, El Hajbi, Farid, Di Bartolomeo, Maria, Braghiroli, Maria Ignez Freitas Melro, Holtved, Eva, Blum Murphy, Mariela A., Abdullaev, Sandzhar, Soleymani, Samira, Lei, Ming, Kato, Ken, Kitagawa, Yuko

“…4035 Background: NIVO + chemo and NIVO + IPI demonstrated significant overall survival (OS) benefit vs chemo in previously untreated patients (pts) with…”
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Proton pump inhibitors and antibiotics impact on toxicities and clinical outcomes in cancer patients treated with immunotherapy by Araujo, Haniel alves, Moniz, Camila Motta Venchiarutti, Braghiroli, Oddone Freitas Melro, Mak, Milena Perez, Uratani, Lucas Fernando, Dahmer Tiecher, Ricardo, Moraes, Priscila Muniz, Barbosa, Ingrid, Camargo, Veridiana Pires De, Braghiroli, Maria Ignez Freitas Melro, Castro, Gilberto, Hoff, Paulo Marcelo, Diz, Maria Del Pilar

“…Abstract only 2652 Background: Gut microbiome dysbiosis impairs systemic immune responses and recent evidence suggests its critical role in patients (pts)…”
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Pembrolizumab with or without chemotherapy versus chemotherapy for advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma: The phase III KEYNOTE-062 study by Tabernero, Josep, Van Cutsem, Eric, Bang, Yung-Jue, Fuchs, Charles S., Wyrwicz, Lucjan, Lee, Keun Wook, Kudaba, Iveta, Garrido, Marcelo, Chung, Hyun Cheol, Castro Salguero, Hugo Raul, Mansoor, Wasat, Braghiroli, Maria Ignez Freitas Melro, Goekkurt, Eray, Chao, Joseph, Wainberg, Zev A., Kher, Uma, Shah, Sukrut, Kang, SoonMo Peter, Shitara, Kohei

“…Abstract only LBA4007 Background: KEYNOTE062 (NCT02494583) was a randomized, active controlled study of 1L P or P+C vs C in pts with PD-L1 combined positive…”
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Genomic profiling and efficacy of anti-EGFR therapy in appendiceal adenocarcinoma by Braghiroli, Maria Ignez Freitas Melro, Nash, Garrett Michael, Morris, Martin, Hechtman, Jaclyn Frances, Vakiani, Efsevia, Berger, Michael F., Solit, David B., Saltz, Leonard, Cercek, Andrea

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Genomic profiling and efficacy of anti-EGFR therapy in appendiceal adenocarcinoma by Braghiroli, Maria Ignez Freitas Melro, Nash, Garrett Michael, Morris, Martin, Hechtman, Jaclyn Frances, Vakiani, Efsevia, Berger, Michael F., Solit, David B., Saltz, Leonard, Cercek, Andrea

“…Abstract only 574 Background: Metastatic appendiceal adenocarcinoma (AAC) is a heterogenous disease and the majority of patients present with diffuse…”
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Pretreatment neutrophil to lymphocyte ratio and prognosis of patients with advanced hepatocelullar carcinoma treated with sorafenib by Fonseca, Leonardo Gomes, Barroso-Sousa, Romualdo, Blanco, Bruna Paccola, Valente, Gabriel Luis, Braghiroli, Maria Ignez Freitas Melro, Pfiffer, Tulio Eduardo Flesch, Sabbaga, Jorge, Hoff, Paulo Marcelo

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A phase II trial of metformin and fluorouracil (MetFU) for patients (pts) with metastatic colorectal cancer (mCRC) refractory to standard treatment by Miranda, Vanessa Costa, Faria, Luiza Dib, Braghiroli, Maria Ignez Freitas Melro, Jacobs, Monica, Sabbaga, Jorge, Hoff, Paulo Marcelo, Riechelmann, Rachel Pimenta

“…Abstract only 601 Background: Pts with mCRC whose disease progressed after 5-FU, oxaliplatin, irinotecan and monoclonal antibodies have an unmet medical need…”
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Bevacizumab (BEV)-based therapy in the treatment of recurrent glioblastoma (GBM) in patients (PTS) treated at a Brazilian cancer center by Munhoz, Rodrigo Ramella, Braghiroli, Maria Ignez Freitas Melro, Rego, Juliana Florinda De Mendonga, Hoff, Paulo Marcelo, Feher, Olavo, Katz, Artur

“…Abstract only e12513 Background: Temozolomide (TMZ) both concurrently and after radiation therapy constitutes the standard of care for newly diagnosed GBM PTS…”
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Phase II trial of metformin and paclitaxel for patients with gemcitabine-refractory advanced adenocarcinoma of the pancreas by De Celis Ferrari, Anezka Carvalho Rubin, Pfiffer, Tulio Eduardo Flesch, Alex, Alexandra Khichfy, Nebuloni, Daniela R., Carneiro, Allyne Q., Capareli, Fernanda Cunha, Leite, Luiz Antonio Senna, Braghiroli, Maria Ignez Freitas Melro, Lobo, Juliana, Hoff, Paulo Marcelo, Riechelmann, Rachel Pimenta

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Evaluation of predictive biomarkers of response and prognosis in patients with high-grade extrapulmonary neuroendocrine carcinomas treated with platin-based chemotherapy by Rego, Juliana Florinda De Mendonga, Medeiros, Raphael Salles S., Braghiroli, Maria Ignez Freitas Melro, Bezerra Neto, Joao Evangelista, Munhoz, Rodrigo Ramella, Guerra, Juliana Mariotti, Kimura, Lidia, Nonogaki, Suely, Pfiffer, Tulio Eduardo Flesch, Galvao, Breno, Hoff, Paulo Marcelo, Rocha Filho, Duilio, Costa, Frederico, Riechelmann, Rachel Pimenta

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High-grade extrapulmonary neuroendocrine carcinomas and small cell lung cancer: Different entities, same treatment by Rego, Juliana Florinda De Mendonga, Medeiros, Raphael Salles S., Braghiroli, Maria Ignez Freitas Melro, Galvao, Breno, Bezerra Neto, Joao Evangelista, Munhoz, Rodrigo Ramella, Guerra, Juliana Mariotti, Kimura, Lidia, Nonogaki, Suely, Pfiffer, Tulio Eduardo Flesch, Castro, Gilberto, Hoff, Paulo Marcelo, Rocha Filho, Duilio, Costa, Frederico, Riechelmann, Rachel Pimenta

“…Abstract only…”
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