Search Results - "Bragdon, Meghan Dj"
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Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity
Published in eLife (21-06-2019)“…Developmental enhancers integrate graded concentrations of transcription factors (TFs) to create sharp gene expression boundaries. Here we examine the…”
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Journal Article -
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Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo
Published in Proceedings of the National Academy of Sciences - PNAS (20-01-2015)“…Significance Enhancers are regions of regulatory DNA that control gene expression and cell fate decisions during development. Enhancers compute the expression…”
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Journal Article -
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A gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate
Published in Development (Cambridge) (01-02-2015)“…In developing embryos, gene regulatory networks drive cells towards discrete terminal fates, a process called canalization. We studied the behavior of the…”
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Journal Article