Search Results - "Bragado, Maria Julia"

Antioxidants and Male Fertility: from Molecular Studies to Clinical Evidence by Martin-Hidalgo, David, Bragado, Maria Julia, Batista, Ana R, Oliveira, Pedro F, Alves, Marco G

“…Spermatozoa are physiologically exposed to reactive oxygen species (ROS) that play a pivotal role on several sperm functions through activation of different…”
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Quantitative Analysis of the Human Semen Phosphorometabolome by 31P-NMR by Serrano, Rebeca, Martin-Hidalgo, David, Bilbao, Jon, Bernardo-Seisdedos, Ganeko, Millet, Oscar, Garcia-Marin, Luis J., Bragado, Maria Julia

“…Phosphorus-containing metabolites occupy a prominent position in cell pathways. The phosphorometabolomic approach in human sperm samples will deliver valuable…”
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The calcium/CaMKKalpha/beta and the cAMP/PKA pathways are essential upstream regulators of AMPK activity in boar spermatozoa by Hurtado de Llera, Ana, Martin-Hidalgo, David, Gil, Maria Cruz, Garcia-Marin, Luis J, Bragado, Maria Julia

“…Spermatozoa successfully fertilize oocytes depending on cell energy-sensitive processes. We recently showed that the cell energy sensor, the AMP-activated…”
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Calmodulin inhibitors increase the affinity of Merocyanine 540 for boar sperm membrane under non-capacitating conditions by GONZÁLEZ-FERNÁNDEZ, Lauro, MACÍAS-GARCÍA, Beatriz, CALLE-GUISADO, Violeta, GARCÍA-MARÍN, Luis Jesús, BRAGADO, María Julia

“…We aimed to test whether the calmodulin (CaM) inhibitors, calmidazolium (CZ) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), can be used to…”
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The Proteome of Equine Oviductal Fluid Varies Before and After Ovulation: A Comparative Study by Fernández-Hernández, Pablo, Marinaro, Federica, Sánchez-Calabuig, María Jesús, García-Marín, Luis Jesús, Bragado, María Julia, González-Fernández, Lauro, Macías-García, Beatriz

“…Equine fertilization cannot be performed in the laboratory as equine spermatozoa do not cross the oocyte's zona pellucida in vitro . Hence, a more profound…”
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The Calcium/CaMKKalpha/beta and the cAMP/PKA Pathways Are Essential Upstream Regulators of AMPK Activity in Boar Spermatozoa1 by Hurtado de Llera, Ana, Martin-Hidalgo, David, Gil, Maria Cruz, Garcia-Marin, Luis J, Bragado, Maria Julia

“…Spermatozoa successfully fertilize oocytes depending on cell energy-sensitive processes. We recently showed that the cell energy sensor, the AMP-activated…”
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c-Jun N-terminal protein kinase signalling pathway mediates lovastatin-induced rat brain neuroblast apoptosis by Cerezo-Guisado, Maria Isabel, Álvarez-Barrientos, Alberto, Argent, Ricardo, García-Marín, Luis Jesús, Bragado, Maria Julia, Lorenzo, Maria Jesús

“…We have previously shown that lovastatin, an HMG-CoA reductase inhibitor, induces apoptosis in rat brain neuroblasts. c-Jun N-terminal kinase (JNK) and p38…”
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Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts by Cerezo-Guisado, Maria Isabel, García-Román, Natalia, García-Marín, Luis Jesús, Alvarez-Barrientos, Alberto, Bragado, Maria Julia, Lorenzo, Maria Jesús

“…We have shown previously that lovastatin, a 3-hydroxy-3-methyl- glutaryl coenzyme A reductase inhibitor, induces apoptosis in spontaneously immortalized rat…”
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Lovastatin effect in rat neuroblasts of the CNS: inhibition of cap-dependent translation by Santa-Catalina, Marta Olivera, Garcia-Marin, Luis Jesus, Bragado, María Julia

“…Mevalonate biosynthesis pathway is important in cell growth and survival and its blockade by 3-hydroxy-3-methylglutaryl CoA reductase inhibitors, statins,…”
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Stage-specific metabolomic changes in equine oviductal fluid: New insights into the equine fertilization environment by González-Fernández, Lauro, Sánchez-Calabuig, María Jesús, Calle-Guisado, Violeta, García-Marín, Luis Jesús, Bragado, María Julia, Fernández-Hernández, Pablo, Gutiérrez-Adán, Alfonso, Macías-García, Beatriz

“…A repeatable protocol for equine in vitro fertilization (IVF) has remained elusive. This is likely, in part, due to suboptimal composition of capacitation or…”
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The compound YK 3-237 promotes pig sperm capacitation-related events by Martín-Hidalgo, David, Solar-Málaga, Soraya, González-Fernández, Lauro, Zamorano, José, García-Marín, Luis Jesús, Bragado, María Julia

“…Before fertilization of the oocyte, the spermatozoa must undergo through a series of biochemical changes in the female reproductive tract named sperm…”
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Lovastatin inhibits the growth and survival pathway of phosphoinositide 3‐kinase/protein kinase B in immortalized rat brain neuroblasts by Cerezo‐Guisado, Maria Isabel, Garcia‐Marin, Luis Jesus, Lorenzo, Maria Jesus, Bragado, Maria Julia

“…We previously showed that lovastatin, an HMG‐CoA reductase inhibitor, suppresses cell growth by inducing apoptosis in rat brain neuroblasts. Our aim was to…”
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Boar spermatozoa proteomic profile varies in sperm collected during the summer and winter by Martín-Hidalgo, David, Macías-García, Beatriz, García-Marín, Luis Jesús, Bragado, María Julia, González-Fernández, Lauro

“…•Pig spermatozoa proteomics were analysed by nano LC–MS/MS QTof (winter vs. summer).•85 proteins were less abundant in summer.•23 of these protein were related…”
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Effect of boar semen supplementation with recombinant heat shock proteins during summer by Gallardo-Soler, Alejandro, Macías-García, Beatriz, García-Marín, Luis Jesús, Bragado, María Julia, González-Fernández, Lauro

“…Artificial insemination (AI) in pigs is mainly performed with refrigerated boar semen. There is a marked negative seasonal effect on the quality of boar sperm,…”
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Supplementation of freezing/thawing media with GSK3 inhibitor alsterpaullone does not bypass the harmful effect of cryopreservation on boar spermatozoa by Martín-Hidalgo, David, Bragado, María Julia, García-Marín, Luis Jesús, Gil Anaya, María Cruz

“…•Alsterpaullone does not significantly improve post-thaw boar sperm motility.•Alsterpaullone decreases post-thaw boar sperm mitochondrial membrane…”
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Selected Metabolites Found in Equine Oviductal Fluid do not Modify the Parameters Associated to Capacitation of the Frozen-thawed Equine Spermatozoa In Vitro by Fernández-Hernández, Pablo, García-Marín, Luis Jesús, Bragado, María Julia, Domingo, Andrés, González-Fernández, Lauro, Macías-García, Beatriz

“…•Different metabolites found in oviductal fluid were added to thawed equine sperm•Motility, viability, acrosome reaction, and reactive oxygen species were…”
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Glucose prevents the acquisition of the capacitated state in pig spermatozoa by Serrano, Rebeca, Solar Málaga, Soraya, González-Fernández, Lauro, Gervasi, María Gracia, García-Marín, Luis Jesús, Bragado, María Julia, Martin-Hidalgo, David

“…Mammalian spermatozoa need to undergo a process named capacitation to be able to fertilize an oocyte. During their journey in the female tract, spermatozoa…”
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Quantitative Analysis of the Human Semen Phosphorometabolome by [sup.31]P-NMR by Serrano, Rebeca, Ma, Bilbao, Jon, Bernardo-Seisdedos, Ganeko, Millet, Oscar, Garcia-Marin, Luis J, Bragado, Maria Julia

“…Phosphorus-containing metabolites occupy a prominent position in cell pathways. The phosphorometabolomic approach in human sperm samples will deliver valuable…”
Get full text

Quantitative Analysis of the Human Semen Phosphorometabolome by 31 P-NMR by Serrano, Rebeca, Martin-Hidalgo, David, Bilbao, Jon, Bernardo-Seisdedos, Ganeko, Millet, Oscar, Garcia-Marin, Luis J, Bragado, Maria Julia

“…Phosphorus-containing metabolites occupy a prominent position in cell pathways. The phosphorometabolomic approach in human sperm samples will deliver valuable…”
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Growing and regenerating axons in the visual system of teleosts are recognized with the antibody RT97 by Velasco, Almudena, Bragado, Marı́a Julia, Jimeno, David, Caminos, Elena, Lillo, Concepción, Aijón, José, Lara, Juan M.

“…We have analyzed the immunolabeling with the antibody RT97, a good marker for ganglion cell axons in several species, in the normal and regenerating visual…”
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