Search Results - "Bragado, M. J."

Metformin blocks mitochondrial membrane potential and inhibits sperm motility in fresh and refrigerated boar spermatozoa by Hurtado de Llera, A, Martin‐Hidalgo, D, Garcia‐Marin, LJ, Bragado, MJ

“…Contents Metformin is clinically used to treat diabetes. Given its role‐impacting metabolism, metformin has been also added to semen cryopreservation media…”
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Human sperm motility is downregulated by the AMPK activator A769662 by Calle‐Guisado, V., Hurtado de Llera, A., González‐Fernández, L., Bragado, M. J., Garcia‐Marin, L. J.

“…Summary AMP‐activated kinase (AMPK) plays a key function in maintaining cellular energy homeostasis. We recently identified and localized AMPK protein in human…”
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Porcine sperm motility is regulated by serine phosphorylation of the glycogen synthase kinase-3α by Aparicio, I M, Bragado, M J, Gil, M C, Garcia-Herreros, M, Gonzalez-Fernandez, L, Tapia, J A, Garcia-Marin, L J

“…Sperm functions are critically controlled through the phosphorylation state of specific proteins. Glycogen synthase kinase-3 (GSK3) is a serine/threonine…”
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Inter- and intra-breed comparative study of sperm motility and viability in Iberian and Duroc boar semen during long-term storage in MR-A and XCell extenders by Martín-Hidalgo, D, Barón, F.J, Robina, A, Bragado, M.J, Llera, A. Hurtado de, García-Marín, L.J, Gil, M.C

“…During boar semen liquid preservation, extender is one of the factors that influence storage tolerance of spermatozoa. However, there are few studies about…”
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Phosphatidylinositol 3-kinase pathway regulates sperm viability but not capacitation on boar spermatozoa by Aparicio, I.M., Bragado, M.J., Gil, M.C., Garcia-Herreros, M., Gonzalez-Fernandez, L., Tapia, J.A., Garcia-Marin, L.J.

“…Phosphatidylinositol 3‐kinase (PI3‐K) plays an important role in cell survival in somatic cells and recent data pointed out a role for this kinase in sperm…”
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Platelet-activating Factor in Iberian Pig Spermatozoa: Receptor Expression and Role as Enhancer of the Calcium-Induced Acrosome Reaction by Bragado, MJ, Gil, MC, Garcia-Marin, LJ

“…Contents Platelet‐activating factor (PAF) is a phospholipid involved in reproductive physiology. PAF receptor is expressed in some mammalian spermatozoa…”
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Metformin inhibits human spermatozoa motility and signalling pathways mediated by protein kinase A and tyrosine phosphorylation without affecting mitochondrial function by Calle-Guisado, V, Gonzalez-Fernandez, L, Martin-Hidalgo, D, Garcia-Marin, L J, Bragado, M J

“…Metformin is a leading antidiabetic drug that is used worldwide in the treatment of diabetes mellitus. This biguanide exerts metabolic and pleiotropic effects…”
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New insights into transduction pathways that regulate boar sperm function by Hurtado de Llera, A., Martin-Hidalgo, D., Gil, M.C., Garcia-Marin, L.J., Bragado, M.J.

“…Detailed molecular mechanisms mediating signal transduction cascades that regulate boar sperm function involving Ser/Thr and tyrosine phosphorylation of…”
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HSP90 maintains boar spermatozoa motility and mitochondrial membrane potential during heat stress by Calle-Guisado, V., Bragado, M.J., García-Marín, L.J., González-Fernández, L.

“…•A protective effect of HSP90 on boar sperm subjected to heat stress is demonstrated.•HSP90 inhibition by 17-AAG decreases boar sperm motility in…”
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AMPK up-activation reduces motility and regulates other functions of boar spermatozoa by Hurtado de Llera, A, Martin-Hidalgo, D, Gil, M C, Garcia-Marin, L J, Bragado, M J

“…We recently demonstrated that AMPK inhibition in spermatozoa regulates motility, plasma membrane organization, acrosome integrity and mitochondrial membrane…”
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Iatrogenic pulmonary pseudoaneurysm rupture following thoracic drainage by Marco Escoto, M J, Navarrete Rebollo, M L, Prieto Bragado, M J, Alvarado Ramírez, J D, Fernández López, I, Carrasco Barea, J M

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The effect of melatonin on the quality of extended boar semen after long-term storage at 17 °C by Martín-Hidalgo, D., Barón, F.J., Bragado, M.J., Carmona, P., Robina, A., García-Marín, L.J., Gil, M.C.

“…Melatonin (MLT) is an efficient antioxidant that protects cells and tissues and initiates a host of receptor-mediated effects. In order to enhance the life…”
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Regulation of protein synthesis by cholecystokinin in rat pancreatic acini involves PHAS-I and the p70 S6 kinase pathway by Bragado, M.Julia, Groblewski, Guy E., Williams ,‡, John A.

“…Background & Aims: Cholecystokinin (CCK) stimulates protein synthesis in pancreatic acini at the translational level, although the signaling mechanisms…”
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Hepatocyte growth factor activates several transduction pathways in rat pancreatic acini by Aparicio, I.M, Garcia-Marin, L.J, Andreolotti, A.G, Bodega, G, Jensen, R.T, Bragado, M.J

“…The receptor of hepatocyte growth factor (HGF), c-met induces different physiological responses in several cell types. Little is known about the role of HGF in…”
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Protein kinase C activity in boar sperm by Teijeiro, J. M., Marini, P. E., Bragado, M. J., Garcia‐Marin, L. J.

“…Summary Male germ cells undergo different processes within the female reproductive tract to successfully fertilize the oocyte. These processes are triggered by…”
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A new Bayesian network‐based approach to the analysis of sperm motility: application in the study of tench (Tinca tinca) semen by Gil Anaya, M. C., Calle, F., Pérez, C. J., Martín‐Hidalgo, D., Fallola, C., Bragado, M. J., García‐Marín, L. J., Oropesa, A. L.

“…Summary In this study a Bayesian network (BN) has been built for the study of the objective motility of Tinca tinca spermatozoa (spz). Semen from eight…”
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Impairment of intracellular calcium homoeostasis in the exocrine pancreas after caerulein-induced acute pancreatitis in the rat by Bragado, M J, San Román, J I, González, A, García, L J, López, M A, Calvo, J J

“…1. We have measured intracellular calcium concentrations in basal conditions and in response to cholecystokinin-octapeptide and acetylcholine in pancreatic…”
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p70s6k is activated by CCK in rat pancreatic acini by Bragado, M J, Groblewski, G E, Williams, J A

“…The expression and activity of p70s6k-p85s6k in isolated rat pancreatic acini were revealed by Western blotting, immunoprecipitation, and kinase assay…”
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Protective effect of long term high fiber diet consumption on rat exocrine pancreatic function after chronic ethanol intake by Bragado, Marı́a J., Garcı́a, Luis J., López, Marı́a A., Calvo, José J.

“…The effects of ethanol administration on exocrine pancreas have been widely studied, but little is known about the effect of dietary fiber in combination with…”
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A Role for the p38 Mitogen-activated Protein Kinase/Hsp 27 Pathway in Cholecystokinin-induced Changes in the Actin Cytoskeleton in Rat Pancreatic Acini by Schäfer, Claus, Ross, Sarah E., Bragado, M. Julia, Groblewski, Guy E., Ernst, Stephen A., Williams, John A.

“…Cholecystokinin (CCK) and other pancreatic secretagogues have recently been shown to activate signaling kinase cascades in pancreatic acinar cells, leading to…”
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