Search Results - "Braga, Marilia D. V."
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Computing the family-free DCJ similarity
Published in BMC bioinformatics (08-05-2018)“…The genomic similarity is a large-scale measure for comparing two given genomes. In this work we study the (NP-hard) problem of computing the genomic…”
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Efficient gene orthology inference via large-scale rearrangements
Published in Algorithms for molecular biology (28-09-2023)“…Abstract Background Recently we developed a gene orthology inference tool based on genome rearrangements ( Journal of Bioinformatics and Computational Biology…”
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Investigating the complexity of the double distance problems
Published in Algorithms for molecular biology (04-01-2024)“…Two genomes [Formula: see text] and [Formula: see text] over the same set of gene families form a canonical pair when each of them has exactly one gene from…”
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Whole-Genome Analysis of Transporters in the Plant Pathogen Xylella fastidiosa
Published in Microbiology and Molecular Biology Reviews (01-06-2002)“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genomic Distance with High Indel Costs
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-05-2017)“…We determine complexity of computing the DCJ-indel distance, when DCJ and indel operations have distinct constant costs, by showing an exact formula that can…”
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Natural family-free genomic distance
Published in Algorithms for molecular biology (10-05-2021)“…A classical problem in comparative genomics is to compute the rearrangement distance, that is the minimum number of large-scale rearrangements required to…”
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Footprints of inversions at present and past pseudoautosomal boundaries in human sex chromosomes
Published in Genome biology and evolution (01-01-2009)“…The human sex chromosomes have stopped recombining gradually, which has left five evolutionary strata on the X chromosome. Y inversions are thought to have…”
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baobabLUNA: the solution space of sorting by reversals
Published in Bioinformatics (15-07-2009)“…Computing the reversal distance and searching for an optimal sequence of reversals to transform a unichromosomal genome into another are useful algorithmic…”
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Computing the Inversion-Indel Distance
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-11-2021)“…The inversion distance, that is the distance between two unichromosomal genomes with the same content allowing only inversions of DNA segments, can be exactly…”
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Family-Free Genome Comparison
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…The comparison of large-scale genome structures across distinct species offers valuable insights into the species' phylogeny, genome organization, and gene…”
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On the inversion-indel distance
Published in BMC bioinformatics (2013)“…The inversion distance, that is the distance between two unichromosomal genomes with the same content allowing only inversions of DNA segments, can be computed…”
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Restricted DCJ-indel model: sorting linear genomes with DCJ and indels
Published in BMC bioinformatics (2012)“…The double-cut-and-join (DCJ) is a model that is able to efficiently sort a genome into another, generalizing the typical mutations (inversions, fusions,…”
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Double cut and join with insertions and deletions
Published in Journal of computational biology (01-09-2011)“…Many approaches to compute the genomic distance are still limited to genomes with the same content, without duplicated markers. However, differences in the…”
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An asymmetric approach to preserve common intervals while sorting by reversals
Published in Algorithms for molecular biology (30-12-2009)“…The reversal distance and optimal sequences of reversals to transform a genome into another are useful tools to analyse evolutionary scenarios. However, the…”
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Sorting Linear Genomes with Rearrangements and Indels
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-05-2015)“…Rearrangements are mutations that can change the organization of a genome, but not its content. Examples are inversions of DNA segments, translocations of…”
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On the weight of indels in genomic distances
Published in BMC bioinformatics (05-10-2011)“…Classical approaches to compute the genomic distance are usually limited to genomes with the same content, without duplicated markers. However, differences in…”
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Genomic distance under gene substitutions
Published in BMC bioinformatics (05-10-2011)“…The distance between two genomes is often computed by comparing only the common markers between them. Some approaches are also able to deal with non-common…”
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On the family-free DCJ distance and similarity
Published in Algorithms for molecular biology (01-04-2015)“…Structural variation in genomes can be revealed by many (dis)similarity measures. Rearrangement operations, such as the so called double-cut-and-join (DCJ),…”
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Repetition-free longest common subsequence
Published in Discrete Applied Mathematics (28-06-2010)“…We study the following problem. Given two sequences x and y over a finite alphabet, find a repetition-free longest common subsequence of x and y . We show…”
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Computing the Rearrangement Distance of Natural Genomes
Published in Journal of computational biology (01-04-2021)“…The computation of genomic distances has been a very active field of computational comparative genomics over the past 25 years. Substantial results include the…”
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