Search Results - "Braga, Fernão C."

(3,3″)-Linked Biflavanones from Ouratea spectabilis and Their Effects on the Release of Proinflammatory Cytokines in THP‑1 Cells by Rocha, Marina P, Campana, Priscilla R. V, Pádua, Rodrigo M, Souza Filho, José D, Ferreira, Daneel, Braga, Fernão C

“…Ouratea spectabilis is an arborous species traditionally used in Brazil as an anti-inflammatory agent. Four new (3,3″)-linked biflavanone O-methyl ethers,…”
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Mansoins C–F, Oligomeric Flavonoid Glucosides Isolated from Mansoa hirsuta Fruits with Potential Anti-inflammatory Activity by Campana, Priscilla R. V, Coleman, Christina M, Sousa, Lirlândia P, Teixeira, Mauro M, Ferreira, Daneel, Braga, Fernão C

“…Continued investigation of the polyphenolic pool of the fruits of Mansoa hirsuta afforded four additional members of the new class of glucosylated oligomeric…”
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Chemical characterization and antiherpes activity of sulfated polysaccharides from Lithothamnion muelleri by Malagoli, Bruna G., Cardozo, Francielle T.G.S., Gomes, Jose Hugo S., Ferraz, Vany P., Simões, Cláudia M.O., Braga, Fernão C.

“…We report herein the chemical characterization and antiherpes activity of polysaccharides from the red alga Lithothamnion muelleri (Hapalidiaceae). The…”
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Selective Inhibition of Aromatase by a Dihydroisocoumarin from Xyris pterygoblephara by Endringer, Denise C, Guimarães, Keller G, Kondratyuk, Tamara P, Pezzuto, John M, Braga, Fernão C

“…Aromatase is a well-established target for the chemoprevention of breast cancer. The dihydroisocoumarin…”
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TNF‑α Inhibition Elicited by Mansoins A and B, Heterotrimeric Flavonoids Isolated from Mansoa hirsuta by Campana, Priscilla R. V, Coleman, Christina M, Teixeira, Mauro M, Ferreira, Daneel, Braga, Fernão C

“…Mansoins A (1) and B (2) isolated from the fruits of Mansoa hirsuta represent new glucosylated heterotrimeric flavonoids with a flavanone core linked to two…”
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Lithothamnion muelleri treatment ameliorates inflammatory and hypernociceptive responses in antigen-induced arthritis in mice by Costa, Vivian V, Amaral, Flavio A, Coelho, Fernanda M, Queiroz-Junior, Celso M, Malagoli, Bruna G, Gomes, Jose Hugo S, Lopes, Fernando, Silveira, Kátia D, Sachs, Daniela, Fagundes, Caio T, Tavares, Lívia D, Pinho, Vanessa, Silva, Tarcilia A, Teixeira, Mauro M, Braga, Fernão C, Souza, Danielle G

“…Rheumatoid Arthritis (RA) is a chronic disease characterized by persistent inflammation and pain. Alternative therapies to reduce these symptoms are needed…”
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Nitric oxide-dependent vasodilatation by ethanolic extract of Hancornia speciosa via phosphatidyl-inositol 3-kinase by Ferreira, Herick C., Serra, Carla P., Lemos, Virginia S., Braga, Fernão C., Cortes, Steyner F.

“…The vasodilator effect of the ethanolic extract of leaves from Hancornia speciosa Gomes (HSE) was studied in rat aortic rings. HSE produced a…”
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Anti-biofilm activity of Marula – A study with the standardized bark extract by Sarkar, Ratul, Chaudhary, Sushil K., Sharma, Amrita, Yadav, Kirendra K., Nema, Neelesh K., Sekhoacha, Mamello, Karmakar, Sanmoy, Braga, Fernão C., Matsabisa, Motlalepula Gilbert, Mukherjee, Pulok K., Sen, Tuhinadri

“…Marula (Sclerocarya birrea; family – Anacardiaceae) is an African plant, which enjoys wide socio-economic importance particularly in southern part of Africa…”
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Bioguided chemical characterization of pequi (Caryocar brasiliense) fruit peels towards an anti-diabetic activity by Caldeira, Alisson S.P., Mbiakop, Ulrich C., Pádua, Rodrigo M., van de Venter, Maryna, Matsabisa, Motlalepula G., Campana, Priscilla R.V., Cortes, Steyner F., Braga, Fernão C.

“…•The antidiabetic potential of Caryocar brasiliense fruit peel extract was assessed.•Bioactive fractions were identified by cytokines and digestive enzymes…”
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Oral sub-chronic treatment with Terminalia phaeocarpa Eichler (Combretaceae) reduces liver PTP1B activity in a murine model of diabetes by Mbiakop, Ulrich C., Gomes, José H.S., Pádua, Rodrigo M., Lemos, Virgínia S., Braga, Fernão C., Cortes, Steyner F.

“…The endemic Brazilian medicinal plants of the genus Terminalia (Combretaceae), popularly known as capitão, comprising the similar species Terminalia phaeocarpa…”
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Ouratea spectabilis and its Biflavanone Ouratein D Exert Potent Anti-inflammatory Activity in MSU Crystal-induced Gout in Mice by Rocha, Marina P, Oliveira, Diego P, de Oliveira, Vivian L S, Zaidan, Isabella, Grossi, Laís C, Campana, Priscilla R V, Amaral, Flávio A, Sousa, Lirlândia P, Teixeira, Mauro M, Braga, Fernão C

“…Gouty arthritis (GA) is an inflammatory arthritis triggered by the deposition of monosodium urate monohydrate (MSU) crystals, causing pain, inflammation, and…”
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Determination of l-(+)-bornesitol, the hypotensive constituent of Hancornia speciosa, in rat plasma by LC-MS/MS and its application on a pharmacokinetic study by Moreira, Luciana N., Feltrin, Clarissa, Gonçalves, José E., de Castro, Whocely V., Simões, Cláudia M.O., de Pádua, Rodrigo M., Cortes, Steyner F., Braga, Fernão C.

“…[Display omitted] •An UPLC-ESI-MS/MS method was developed to quantify bornesitol in rat plasma.•Pharmacokinetic of bornesitol was evaluated after intravenous…”
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The Cyclitol L-(+)-Bornesitol as an Active Marker for the Cardiovascular Activity of the Brazilian Medicinal Plant Hancornia speciosa by Moreira, Luciana N., Silva, Grazielle C., Câmara, Diógenes V., Pádua, Rodrigo M., Lemos, Virgínia S., Braga, Fernão C., Cortes, Steyner F.

“…The cyclitol bornesitol is the main constituent of the leaves from the antihypertensive medicinal plant Hancornia speciosa. This study aimed to investigate the…”
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Inhibition of the sphingosine‐1‐phosphate pathway promotes the resolution of neutrophilic inflammation by Perez, Denise A., Galvão, Izabela, Athayde, Rayssa M., Rezende, Barbara M., Vago, Juliana P., Silva, Julia D., Reis, Alesandra C., Ribeiro, Lucas S., Gomes, José H. S., Pádua, Rodrigo M., Braga, Fernão C., Sousa, Lirlândia P., Teixeira, Mauro M., Pinho, Vanessa

“…Sphingosine‐1‐phosphate (S1P) is an important sphingolipid derived from plasma membrane and has a known role in productive phase of inflammation, but its role…”
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Cytotoxic effects of the cardenolide convallatoxin and its Na,K-ATPase regulation by Schneider, Naira Fernanda Zanchett, Silva, Izabella Thais, Persich, Lara, de Carvalho, Annelise, Rocha, Sayonarah C., Marostica, Lucas, Ramos, Ana Carolina Pacheco, Taranto, Alex G., Pádua, Rodrigo M., Kreis, Wolfgang, Barbosa, Leandro A., Braga, Fernão C., Simões, Cláudia M. O.

“…Cardenolides are cardiac glycosides, mostly obtained from natural sources. They are well known for their inhibitory action on the Na,K-ATPase, an effect that…”
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Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death by Schneider, Naira F Z, Cerella, Claudia, Lee, Jin-Young, Mazumder, Aloran, Kim, Kyung Rok, de Carvalho, Annelise, Munkert, Jennifer, Pádua, Rodrigo M, Kreis, Wolfgang, Kim, Kyu-Won, Christov, Christo, Dicato, Mario, Kim, Hyun-Jung, Han, Byung Woo, Braga, Fernão C, Simões, Cláudia M O, Diederich, Marc

“…Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential…”
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Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase by Schneider, Naira Fernanda Zanchett, Persich, Lara, Rocha, Sayonarah C., Ramos, Ana Carolina Pacheco, Cortes, Vanessa Faria, Silva, Izabella Thaís, Munkert, Jennifer, Pádua, Rodrigo M., Kreis, Wolfgang, Taranto, Alex G., Barbosa, Leandro A., Braga, Fernão C., Simões, Cláudia M.O.

“…[Display omitted] •DGX potently inhibits the growth of NSCLC cells.•DGX strongly induced cytotoxic effects on H460 cells.•DGX induced cytostatic effects on…”
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Anti-TNF-α Activity of Brazilian Medicinal Plants and Compounds from Ouratea semiserrata by Campana, Priscilla R. V., Mansur, Daniel S., Gusman, Grasielle S., Ferreira, Daneel, Teixeira, Mauro M., Braga, Fernão C.

“…Several plant species are used in Brazil to treat inflammatory diseases and associated conditions. TNF‐α plays a pivotal role on inflammation, and several…”
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Ursolic Acid Incorporation Does Not Prevent the Formation of a Non-lamellar Phase in pH-Sensitive and Long-Circulating Liposomes by Lopes, Sávia C. A, Novais, Marcus V. M, Ferreira, Diêgo S, Braga, Fernão C, Magalhães-Paniago, Rogério, Malachias, Ângelo, Oliveira, Mônica C

“…Ursolic acid (UA) is a triterpene found in different plant species that has been shown to possess significant antitumor activity. However, UA presents a low…”
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Inhibition of cell proliferation, invasion and migration by the cardenolides digitoxigenin monodigitoxoside and convallatoxin in human lung cancer cell line by Schneider, Naira F. Z., Geller, Fabiana C., Persich, Lara, Marostica, Lucas L., Pádua, Rodrigo M., Kreis, Wolfgang, Braga, Fernão C., Simões, Cláudia M. O.

“…Cardiac glycosides consist of a large family of naturally derived compounds that are clinically used to treat congestive heart failure, and also present…”
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