Search Results - "Braga, Carolina A. C."

Nonspecific Prion Protein–Nucleic Acid Interactions Lead to Different Aggregates and Cytotoxic Species by Macedo, Bruno, Millen, Thiago A, Braga, Carolina A. C. A, Gomes, Mariana P. B, Ferreira, Priscila S, Kraineva, Julia, Winter, Roland, Silva, Jerson L, Cordeiro, Yraima

“…A misfolded form of the prion protein (PrP) is the primary culprit in mammalian prion diseases. It has been shown that nucleic acids catalyze the misfolding of…”
Get full text

Effects on insulin adsorption due to zinc and strontium substitution in hydroxyapatite by Scudeller, Luisa A., Mavropoulos, Elena, Tanaka, Marcelo N., Costa, Andrea M., Braga, Carolina A.C., López, Elvis O., Mello, Alexandre, Rossi, Alexandre M.

“…Insulin-loaded calcium phosphate nanoparticles have been proposed as a potential drug delivery system for the oral treatment of diabetes and to stimulate bone…”
Get full text

An Aggregation-Prone Intermediate Species Is Present in the Unfolding Pathway of the Monomeric Portal Protein of Bacteriophage P22:  Implications for Portal Assembly by Braga, Carolina A. C. A, Carvalho, Danielle, Lara, Flávio Alves, Cortines, Juliana Reis, Moore, Sean D, Prevelige, Peter E, Foguel, Debora

“…The head of the P22 bacteriophage is interrupted by a unique dodecameric portal vertex that serves as a conduit for the entrance and exit of the DNA. Here, the…”
Get full text

Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids by Chaves, Juliana A. P., Sanchez-López, Carolina, Gomes, Mariana P. B., Sisnande, Tháyna, Macedo, Bruno, de Oliveira, Vanessa End, Braga, Carolina A. C., Rangel, Luciana P., Silva, Jerson L., Quintanar, Liliana, Cordeiro, Yraima

“…Conversion of prion protein (PrP) to an altered conformer, the scrapie PrP (PrP Sc ), is a critical step in the development of transmissible spongiform…”
Get full text

Ca(2+) and Mg(2+) binding to weak sites of TnC C-domain induces exposure of a large hydrophobic surface that leads to loss of TnC from the thin filament by Braga, Carolina A C A, Pinto, José Renato, Valente, Ana Paula, Silva, Jerson L, Sorenson, Martha M, Foguel, Débora, Suarez, Marisa C

“…The C-domain of troponin C, the Ca(2+)-binding subunit of the troponin complex, has two high-affinity sites for Ca(2+) that also bind Mg(2+) (Ca(2+)/Mg(2+)…”
Get full text