Search Results - "Braga, Antônio Luiz"

Novel Probucol Analogue, 4,4′-Diselanediylbis (2,6-Di-tert-Butylphenol), Prevents Oxidative Glutamate Neurotoxicity In Vitro and Confers Neuroprotection in a Rodent Model of Ischemic Stroke by Jacques, Mauricio Tavares, de Souza, Viviane, Barbosa, Flávio Augusto Rocha, Faria Santos Canto, Rômulo, Lopes, Samantha Cristiane, Prediger, Rui Daniel, Braga, Antônio Luiz, Aschner, Michael, Farina, Marcelo

“…Oxidative glutamate toxicity is regarded as one of the injurious mechanisms associated with ischemic stroke, which represents a major health problem and…”
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The Thiol-Modifier Effects of Organoselenium Compounds and Their Cytoprotective Actions in Neuronal Cells by Galant, Letícia Selinger, Rafique, Jamal, Braga, Antônio Luiz, Braga, Felipe Camargo, Saba, Sumbal, Radi, Rafael, da Rocha, João Batista Teixeira, Santi, Claudio, Monsalve, Maria, Farina, Marcelo, de Bem, Andreza Fabro

“…Most pharmacological studies concerning the beneficial effects of organoselenium compounds have focused on their ability to mimic glutathione peroxidase (GPx)…”
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Dihydropyrimidinone-derived selenoesters efficacy and safety in an in vivo model of Aβ aggregation by Pereira, Flávia Suelen de Oliveira, Barbosa, Flavio Augusto Rocha, Canto, Rômulo Farias Santos, Lucchese, Cristiane, Pinton, Simone, Braga, Antônio Luiz, Azeredo, Juliano Braun de, Quines, Caroline Brandão, Ávila, Daiana Silva

“…Multi-target mechanisms of FA90 compound. APP= Amyloid Precursor Protein; sAPPβ= Soluble Amyloid Precursor Protein-β; Aβ= Amyloid-beta peptide;LAChrs=…”
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Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds by Naime, Aline Aita, Barbosa, Flavio Augusto Rocha, Bueno, Diones Caeran, Curi Pedrosa, Rozangela, Canto, Rômulo Faria Santos, Colle, Dirleise, Braga, Antônio Luiz, Farina, Marcelo

“…Ferroptosis, an iron-dependent form of cell death, has critical roles in diverse pathologies. Data on the temporal events mediating the prevention of…”
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New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells by Bueno, Diones Caeran, Canto, Rômulo Faria Santos, de Souza, Viviane, Andreguetti, Rafaela Rafognatto, Barbosa, Flávio Augusto Rocha, Naime, Aline Aita, Dey, Partha Narayan, Wüllner, Verena, Lopes, Mark William, Braga, Antônio Luiz, Methner, Axel, Farina, Marcelo

“…Probucol, a hypocholesterolemic compound, is neuroprotective in several models of neurodegenerative diseases but has serious adverse effects in vivo. We now…”
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Antioxidant activity of β-selenoamines and their capacity to mimic different enzymes by de Souza Prestes, Alessandro, Stefanello, Sílvio Terra, Salman, Syed M., Pazini, Andréia Martini, Schwab, Ricardo S., Braga, Antônio Luiz, de Vargas Barbosa, Nilda Berenice, Rocha, João B. T.

“…The antioxidant properties of organoselenium compounds have been extensively investigated because oxidative stress is a hallmark of a variety of chronic human…”
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Facilitation of long-term object recognition memory by pretraining administration of diphenyl diselenide in mice by Rosa, Renato M., Flores, Debora G., Appelt, Helmoz R., Braga, Antônio Luiz, Henriques, João Antônio Pêgas, Roesler, Rafael

“…Selenium compounds display antioxidant and neuroprotective properties. Diphenyl diselenide (PhSe) 2 is an organic selenium compound that affects a number of…”
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Antioxidant activity of [beta]-selenoamines and their capacity to mimic different enzymes by Prestes, Alessandro de Souza, Stefanello, Silvio Terra, Salman, Syed M, Pazini, Andreia Ma, Schwab, Ricardo S, Braga, Antonio Luiz, Barbosa, Nilda Berenice de Vargas, Rocha, Joao B.T

“…The antioxidant properties of organoselenium compounds have been extensively investigated because oxidative stress is a hallmark of a variety of chronic human…”
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Zn in ionic liquid: an efficient reaction media for the synthesis of diorganyl chalcogenides and chalcogenoesters by Narayanaperumal, Senthil, Alberto, Eduardo E., Gul, Kashif, Kawasoko, Cristiane Yuriko, Dornelles, Luciano, Rodrigues, Oscar E.D., Braga, Antonio Luiz

“…A straightforward and efficient methodology is described to synthesize structurally diverse diorganyl selenides, sulfides, seleno- and thioesters by using…”
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Synthesis and biological evaluation of 2-picolylamide-based diselenides with non-bonded interactions by Rafique, Jamal, Saba, Sumbal, Canto, Rômulo Faria Santos, Frizon, Tiago Elias Allievi, Hassan, Waseem, Waczuk, Emily Pansera, Jan, Maryam, Back, Davi Fernando, Da Rocha, João Batista Teixeira, Braga, Antonio Luiz

“…In this paper, we report the synthesis and biological evaluation of picolylamide-based diselenides with the aim of developing a new series of diselenides with…”
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Bimetallic system for the synthesis of diorganyl selenides and sulfides, chiral β-seleno amines, and seleno- and thioesters by Gul, Kashif, Narayanaperumal, Senthil, Dornelles, Luciano, Rodrigues, Oscar E.D., Braga, Antonio Luiz

“…The bimetallic reagent Sn(II)/Cu(II) in [bmim]BF4 was efficiently used for the cleavage of diaryl diselenides and disulfides and reacts with a variety of…”
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Substituent, structural and positional isomerisation alter anti-oxidant activity of organochalcogen compounds in rats’ brain preparations by Hassan, Waseem, Narayanaperumal, Senthil, Gul, Kashif, Braga, Antonio Luiz, Rodrigues, Oscar Dorneles, da Rocha, Joao Batista Teixeira

“…The objective of the present study was to elucidate the biochemical potencies of eighteen structurally related organoselenium and organosulfur compounds…”
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Selenium-Containing (Hetero)Aryl Hybrids as Potential Antileishmanial Drug Candidates: In Vitro Screening against L. amazonensis by Fermiano, Maria Helena, das Neves, Amarith Rodrigues, da Silva, Fernanda, Barros, Manuella Salustiano Andrade, Vieira, Camila Barbosa, Stein, André L, Frizon, Tiago Elias Allievi, Braga, Antonio Luiz, de Arruda, Carla Cardozo Pinto, Parisotto, Eduardo Benedetti, Saba, Sumbal, Rafique, Jamal, Riul, Thalita Bachelli

“…Leishmaniasis remains a significant global health concern, with current treatments relying on outdated drugs associated with high toxicity, lengthy…”
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Metal-Free Air Oxidation of Thiols in Recyclable Ionic Liquid: A Simple and Efficient Method for the Synthesis of Disulfides by Singh, Devender, Galetto, Fábio Z., Soares, Letiére C., Rodrigues, Oscar E. Dorneles, Braga, Antonio Luiz

“…An efficient procedure for the oxidative coupling of alkyl, aryl and heteroaryl thiols with atmospheric oxygen is reported. The methodology utilizes BMIM‐BF4…”
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An organic selenium compound attenuates apomorphine-induced stereotypy in mice by Machado, Miriana S., Rosa, Renato M., Dantas, Andrea S., Reolon, Gustavo K., Appelt, Helmóz R., Braga, Antônio Luiz, Henriques, João Antonio Pêgas, Roesler, Rafael

“…Selenium compounds display neuroprotective activities mediated at least in part by their antioxidant actions. Oxidative damage has been implicated in…”
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Design, Synthesis, and In Vitro Evaluation of a Novel Probucol Derivative: Protective Activity in Neuronal Cells Through GPx Upregulation by Quispe, Ruth Liliám, Canto, Rômulo Faria Santos, Jaramillo, Michael Lorenz, Barbosa, Flavio Augusto Rocha, Braga, Antônio Luiz, de Bem, Andreza Fabro, Farina, Marcelo

“…Recent studies have shown that probucol (PB), a hipocholesterolemic agent with antioxidant and anti-inflammatory properties, presents neuroprotective…”
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Modular chiral thiazolidine catalysts in asymmetric aryl transfer reactions by Braga, Antonio Luiz, Milani, Priscila, Vargas, Fabrício, Paixão, Márcio W., Sehnem, Jasquer A.

“…Modular chiral thiazolidine derivatives were synthesized in a single step from inexpensive and commercially available starting materials. These ligands…”
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Catálise assimétrica no Brasil: desenvolvimento e potencialidades para o avanço da indústria química brasileira by Braga, Antonio Luiz, Lüdtke, Diogo Seibert, Schneider, Paulo Henrique, Andrade, Leandro Helgueira, Paixão, Márcio Weber

“…The preparation of enantiomerically pure or enriched substances is of fundamental importance to pharmaceutical, food, agrochemical, and cosmetics industries…”
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3'3-Ditrifluoromethyldiphenyl diselenide : A new organoselenium compound with interesting antigenotoxic and antimutagenic activities by DA SILVA MACHADO, Miriana, VIANNA VILLELA, Izabel, MOURA, Dinarajaqueline, MOREIRA ROSA, Renato, SALVADOR, Mirian, LOPES, Norberto P, LUIZ BRAGA, Antonio, ROESLER, Rafael, SAFFI, Jenifer, HENRIQUES, Joso Antonio P

“…The trace element selenium (Se), once known only for its potential toxicity, is now a well-established essential micronutrient for mammals. The organoselenium…”
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KIO4‐mediated Selective Hydroxymethylation/Methylenation of Imidazo‐Heteroarenes: A Greener Approach by Franco, Marcelo Straesser, Saba, Sumbal, Rafique, Jamal, Braga, Antonio Luiz

“…Herein, we report a KIO4‐mediated, sustainable and chemoselective approach for the one‐pot C(sp2)−H bond hydroxymethylation or methylenation of…”
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