Search Results - "Braff, Dana"

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components by Pardee, Keith, Green, Alexander A., Takahashi, Melissa K., Braff, Dana, Lambert, Guillaume, Lee, Jeong Wook, Ferrante, Tom, Ma, Duo, Donghia, Nina, Fan, Melina, Daringer, Nichole M., Bosch, Irene, Dudley, Dawn M., O’Connor, David H., Gehrke, Lee, Collins, James J.

“…The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions. Here,…”
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A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers by Takahashi, Melissa K., Tan, Xiao, Dy, Aaron J., Braff, Dana, Akana, Reid T., Furuta, Yoshikazu, Donghia, Nina, Ananthakrishnan, Ashwin, Collins, James J.

“…There is a need for large-scale, longitudinal studies to determine the mechanisms by which the gut microbiome and its interactions with the host affect human…”
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Antibiotics induce redox-related physiological alterations as part of their lethality by Dwyer, Daniel J, Belenky, Peter A, Yang, Jason H, MacDonald, I Cody, Martell, Jeffrey D, Takahashi, Noriko, Chan, Clement T Y, Lobritz, Michael A, Braff, Dana, Schwarz, Eric G, Ye, Jonathan D, Pati, Mekhala, Vercruysse, Maarten, Ralifo, Paul S, Allison, Kyle R, Khalil, Ahmad S, Ting, Alice Y, Walker, Graham C, Collins, James J

“…Deeper understanding of antibiotic-induced physiological responses is critical to identifying means for enhancing our current antibiotic arsenal. Bactericidal…”
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Synthetic biology platform technologies for antimicrobial applications by Braff, Dana, Shis, David, Collins, James J.

“…The growing prevalence of antibiotic resistance calls for new approaches in the development of antimicrobial therapeutics. Likewise, improved diagnostic…”
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Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality by Lobritz, Michael A, Andrews, Ian W, Braff, Dana, Porter, Caroline B M, Gutierrez, Arnaud, Furuta, Yoshikazu, Cortes, Louis B G, Ferrante, Thomas, Bening, Sarah C, Wong, Felix, Gruber, Charley, Bakerlee, Christopher W, Lambert, Guillaume, Walker, Graham C, Dwyer, Daniel J, Collins, James J

“…β-Lactam antibiotics disrupt the assembly of peptidoglycan (PG) within the bacterial cell wall by inhibiting the enzymatic activity of penicillin-binding…”
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Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality by Takahashi, Noriko, Gruber, Charley C., Yang, Jason H., Liu, Xiaobo, Braff, Dana, Yashaswini, Chittampalli N., Bhubhanil, Sakkarin, Furuta, Yoshikazu, Andreescu, Silvana, Collins, James J., Walker, Graham C.

“…Downstream metabolic events can contribute to the lethality of drugs or agents that interact with a primary cellular target. In bacteria, the production of…”
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Technological Advancements towards Paper-Based Biomolecular Diagnostics by Braff, Dana

“…Clinically tractable diagnostics must be low-cost, rapid, sensitive, easy to use, and adaptable to new targets. With its rational design, synthetic biology…”
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Coordinated regulation of acid resistance in Escherichia coli by Aquino, Patricia, Honda, Brent, Jaini, Suma, Lyubetskaya, Anna, Hosur, Krutika, Chiu, Joanna G, Ekladious, Iriny, Hu, Dongjian, Jin, Lin, Sayeg, Marianna K, Stettner, Arion I, Wang, Julia, Wong, Brandon G, Wong, Winnie S, Alexander, Stephen L, Ba, Cong, Bensussen, Seth I, Bernstein, David B, Braff, Dana, Cha, Susie, Cheng, Daniel I, Cho, Jang Hwan, Chou, Kenny, Chuang, James, Gastler, Daniel E, Grasso, Daniel J, Greifenberger, John S, Guo, Chen, Hawes, Anna K, Israni, Divya V, Jain, Saloni R, Kim, Jessica, Lei, Junyu, Li, Hao, Li, David, Li, Qian, Mancuso, Christopher P, Mao, Ning, Masud, Salwa F, Meisel, Cari L, Mi, Jing, Nykyforchyn, Christine S, Park, Minhee, Peterson, Hannah M, Ramirez, Alfred K, Reynolds, Daniel S, Rim, Nae Gyune, Saffie, Jared C, Su, Hang, Su, Wendell R, Su, Yaqing, Sun, Meng, Thommes, Meghan M, Tu, Tao, Varongchayakul, Nitinun, Wagner, Tyler E, Weinberg, Benjamin H, Yang, Rouhui, Yaroslavsky, Anastasia, Yoon, Christine, Zhao, Yanyu, Zollinger, Alicia J, Stringer, Anne M, Foster, John W, Wade, Joseph, Raman, Sahadaven, Broude, Natasha, Wong, Wilson W, Galagan, James E

“…Enteric Escherichia coli survives the highly acidic environment of the stomach through multiple acid resistance (AR) mechanisms. The most effective system,…”
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Antibiotics induce redox-related physiological alterations as part of their lethality by Dwyer, Daniel J., Belenky, Peter A., Yang, Jason H., MacDonald, I. Cody, Martell, Jeffrey D., Takahashi, Noriko, Chan, Clement T. Y., Lobritz, Michael A., Braff, Dana, Schwarz, Eric G., Ye, Jonathan D., Pati, Mekhala, Vercruysse, Maarten, Ralifo, Paul S., Allison, Kyle R., Khalil, Ahmad S., Ting, Alice Y., Walker, Graham C., Collins, James J.

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