Search Results - "Braeuning, A."

Use of (Q)SAR genotoxicity predictions and fuzzy multicriteria decision-making for priority ranking of ethoxyquin transformation products by Rasinger, J.D., Frenzel, F., Braeuning, A., Bernhard, A., Ørnsrud, R., Merel, S., Berntssen, M.H.G.

“…[Display omitted] •Novel workflow for integration of predictions from multiple (Q)SAR models.•Inclusion of chemical occurrence data for augmented in silico…”
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Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies by Piersma, A.H., Burgdorf, T., Louekari, K., Desprez, B., Taalman, R., Landsiedel, R., Barroso, J., Rogiers, V., Eskes, C., Oelgeschläger, M., Whelan, M., Braeuning, A., Vinggaard, A.M., Kienhuis, A., van Benthem, J., Ezendam, J.

“…This report describes the proceedings of the BfR-RIVM workshop on validation of alternative methods which was held 23 and 24 March 2017 in Berlin, Germany…”
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Evaluation and improvement of QSAR predictions of skin sensitization for pesticides by Braeuning, C., Braeuning, A., Mielke, H., Holzwarth, A., Peiser, M.

“…In vivo skin sensitization assays have to be provided by applicants to the competent authorities in the European Union for the approval of active substances…”
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Characterization of aluminum, aluminum oxide and titanium dioxide nanomaterials using a combination of methods for particle surface and size analysis by Krause, B, Meyer, T, Sieg, H, Kästner, C, Reichardt, P, Tentschert, J, Jungnickel, H, Estrela-Lopis, I, Burel, A, Chevance, S, Gauffre, F, Jalili, P, Meijer, J, Böhmert, L, Braeuning, A, Thünemann, A. F, Emmerling, F, Fessard, V, Laux, P, Lampen, A, Luch, A

“…The application of appropriate analytical techniques is essential for nanomaterial (NM) characterization. In this study, we compared different analytical…”
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Genetic ablation of β-catenin inhibits the proliferative phenotype of mouse liver adenomas by Singh, Y, Port, J, Schwarz, M, Braeuning, A

“…Background: Aberrant activation of Wnt/ β -catenin has been implicated in various cancer-related processes, for example, proliferation or tumour cell survival…”
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AQUALLERG‐ID – Allergendetektion von aquatischen Organismen und Insekten in Lebensmittel by Winkel, M., V., V. Blaschke, Garino, C., Zagon, J., Braeuning, A.

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A prospective whole-mixture approach to assess risk of the food and chemical exposome by Tralau, T, Oelgeschläger, M, Kugler, J, Bloch, D, Braeuning, A, Burgdorf, T, Marx-Stoelting, P, Ritz, V, Schmeisser, S, Trubiroha, A, Zellmer, S, Luch, A, Schönfelder, G, Solecki, R, Hensel, A

“…Many widely used chemicals result in ubiquitous human exposure from multiple sources, including diet. Legislation mainly deals with the toxicological…”
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Application of omics data in regulatory toxicology: report of an international BfR expert workshop by Marx-Stoelting, P., Braeuning, A., Buhrke, T., Lampen, A., Niemann, L., Oelgeschlaeger, M., Rieke, S., Schmidt, F., Heise, T., Pfeil, R., Solecki, R.

“…Advances in omics techniques and molecular toxicology are necessary to provide new perspectives for regulatory toxicology. By the application of modern…”
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The nuclear aryl hydocarbon receptor is involved in regulation of DNA repair and cell survival following treatment with ionizing radiation by Dittmann, K.H., Rothmund, M.C., Paasch, A., Mayer, C., Fehrenbacher, B., Schaller, M., Frauenstein, K., Fritsche, E., Haarmann-Stemmann, T., Braeuning, A., Rodemann, H.P.

“…•Ionizing radiation induces nuclear translocation of AhR.•AhR knockdown hampers formation of γ-H2AX foci.•Nuclear AhR is needed for ATM activation and…”
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Silver nanoparticle, stabilizer and ion influence on the proteome of Caco-2 cells by Juling, S., Lichtenstein, D., Böhmert, L., Niedzwiecka, A., Selve, S., Schümann, M., Thünemann, A., Braeuning, A., Krause, E., Lampen, A.

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The influence of food components during artificial digestion on silver nanoparticles and the impact on their cytotoxicity and uptake in Caco-2 cells by Lichtenstein, D., Ebmeyer, J., Knappe, P., Juling, S., Böhmert, L., Selve, S., Niemann, B., Braeuning, A., Thünemann, A., Lampen, A.

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Gender-specific interplay of signaling through β-catenin and car in the regulation of xenobiotic-induced hepatocyte proliferation by Braeuning, A., Heubach, Y., Schwarz, M.

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Tumor formation in liver of conditional  -catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen by Rignall, B., Braeuning, A., Buchmann, A., Schwarz, M.

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OS01-10Transcriptomics enhanced risk assessment of chemical mixtures by Sprenger, H., Braeuning, A.

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OS01-10: Transcriptomics enhanced risk assessment of chemical mixtures by Sprenger, H., Braeuning, A.

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A 560 yr summer temperature reconstruction for the Western Mediterranean basin based on stable carbon isotopes from Pinus nigra ssp. laricio (Corsica/France) by Szymczak, S, Joachimski, M. M, Bräuning, A, Hetzer, T, Kuhlemann, J

“…The Mediterranean is considered as an area which will be affected strongly by current climate change. However, temperature records for the past centuries which…”
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P11-13 Impact of PFAS on lipid metabolism and cholesterol homeostasis in human liver cells by Sadrabadihaghighi, F., Buhrke, T., Braeuning, A.

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OS01-10 Development of a QSAR model for predicting PPARα activation by PFAS based on human in vitro data by Alker, W., Tsiros, P., Buhrke, T., Sarimveis, H., Braeuning, A.

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P24-08 Material- and size-related uptake and effects of plastic particles after oral ingestion by Paul, M.B., Böhmert, L., Braeuning, A., Sieg, H.

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Okadaic acid-induced changes in xenobiotic-metabolizing enzyme and cytokine expression by Würger, L., Sieg, H., Braeuning, A.

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