Search Results - "Braegelmann, Christine"

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    Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions by Fetter, Tanja, Smith, Paul, Guel, Tugce, Braegelmann, Christine, Bieber, Thomas, Wenzel, Joerg

    Published in Frontiers in immunology (03-03-2020)
    “…Cutaneous lupus erythematosus (CLE) is an interferon (IFN) -driven autoimmune skin disease characterized by an extensive cytotoxic lesional inflammation with…”
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    Journal Article
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    Skin-Associated B Cells in the Pathogenesis of Cutaneous Autoimmune Diseases-Implications for Therapeutic Approaches by Fetter, Tanja, Niebel, Dennis, Braegelmann, Christine, Wenzel, Joerg

    Published in Cells (Basel, Switzerland) (07-12-2020)
    “…B lymphocytes are crucial mediators of systemic immune responses and are known to be substantial in the pathogenesis of autoimmune diseases with cutaneous…”
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    Cutaneous Adverse Reactions to COVID-19 Vaccines: Insights from an Immuno-Dermatological Perspective by Niebel, Dennis, Novak, Natalija, Wilhelmi, Jasmin, Ziob, Jana, Wilsmann-Theis, Dagmar, Bieber, Thomas, Wenzel, Joerg, Braegelmann, Christine

    Published in Vaccines (Basel) (25-08-2021)
    “…(1) Background: Numerous vaccines are under preclinical and clinical development for prevention of severe course and lethal outcome of coronavirus disease 2019…”
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    Journal Article
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    Immunostimulatory Endogenous Nucleic Acids Perpetuate Interface Dermatitis-Translation of Pathogenic Fundamentals Into an In Vitro Model by Braegelmann, Christine, Fetter, Tanja, Niebel, Dennis, Dietz, Lara, Bieber, Thomas, Wenzel, Joerg

    Published in Frontiers in immunology (11-01-2021)
    “…Interface dermatitis is a histopathological pattern mirroring a distinct cytotoxic immune response shared by a number of clinically diverse inflammatory skin…”
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    Journal Article
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    Severe autoimmune hemolytic anemia following immunotherapy with checkpoint inhibitors in two patients with metastatic melanoma: a case report by Fetter, Tanja, Fietz, Simon, Bertlich, Maya, Braegelmann, Christine, de Vos-Hillebrand, Luka, Wenzel, Joerg, Heine, Annkristin, Landsberg, Jennifer, Jansen, Philipp

    Published in Frontiers in immunology (20-03-2024)
    “…Over the past decade, immune checkpoint inhibitors such as antibodies against cytotoxicity T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death…”
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    Single-Center Clinico-Pathological Case Study of 19 Patients with Cutaneous Adverse Reactions Following COVID-19 Vaccines by Niebel, Dennis, Wenzel, Joerg, Wilsmann-Theis, Dagmar, Ziob, Jana, Wilhelmi, Jasmin, Braegelmann, Christine

    Published in Dermatopathology (Basel, Switzerland) (27-09-2021)
    “…(1) Background: Coronavirus disease 2019 (COVID-19) vaccines are currently employed on a population-wide scale in most countries worldwide. Data about unusual…”
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    Journal Article
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    Annular plaques mimicking Rowell’s syndrome in the course of coronavirus disease 2019 mRNA vaccines: An overlooked phenomenon? by Niebel, Dennis, Wilhelmi, Jasmin, De Vos, Luka, Ziob, Jana, Jaschke, Kristel, Bieber, Thomas, Wenzel, Joerg, Braegelmann, Christine

    Published in Journal of dermatology (01-01-2022)
    “…Effective vaccines for prevention of severe course and lethal outcome of coronavirus disease 2019 have been developed and approved in regulatory rolling and…”
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    Journal Article
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    Current Concepts on Pathogenic Mechanisms and Histopathology in Cutaneous Lupus Erythematosus by Fetter, Tanja, Braegelmann, Christine, de Vos, Luka, Wenzel, Joerg

    Published in Frontiers in medicine (30-05-2022)
    “…Cutaneous lupus erythematosus (CLE) is an interferon (IFN)-driven autoimmune disease that may be limited to the skin or can be associated with systemic lupus…”
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    Bullous Pemphigoid in Patients Receiving Immune-Checkpoint Inhibitors and Psoriatic Patients-Focus on Clinical and Histopathological Variation by Niebel, Dennis, Wilsmann-Theis, Dagmar, Bieber, Thomas, Berneburg, Mark, Wenzel, Joerg, Braegelmann, Christine

    Published in Dermatopathology (Basel, Switzerland) (18-03-2022)
    “…The most common autoimmune blistering disease, bullous pemphigoid (BP), shows an increased prevalence in psoriatic patients and oncologic patients undergoing…”
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    Targeted Therapies in Autoimmune Skin Diseases by Braegelmann, Christine, Niebel, Dennis, Wenzel, Joerg

    Published in Journal of investigative dermatology (01-03-2022)
    “…Unlike the established anti-inflammatory drugs with a broad range, new-targeted therapeutic approaches have emerged in the management of autoimmune skin…”
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    Journal Article
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    Cutaneous Lupus Erythematosus: An Update on Pathogenesis and Future Therapeutic Directions by Niebel, Dennis, de Vos, Luka, Fetter, Tanja, Brägelmann, Christine, Wenzel, Jörg

    Published in American journal of clinical dermatology (01-07-2023)
    “…Lupus erythematosus comprises a spectrum of autoimmune diseases that may affect various organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous…”
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    Journal Article
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    Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus by Scholtissek, Benedikt, Zahn, Sabine, Maier, Judith, Klaeschen, Sophie, Braegelmann, Christine, Hoelzel, Michael, Bieber, Thomas, Barchet, Winfried, Wenzel, Joerg

    Published in Journal of investigative dermatology (01-07-2017)
    “…Cutaneous lupus erythematosus (CLE) is a photosensitive autoimmune disease characterized by a strong type I IFN-associated inflammation. Keratinocytes are…”
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    The Initial Stage of Neutrophilic Dermatosis of the Dorsal Hands: A Case Report and Discussion of Differential Diagnoses by Braegelmann, Christine, Niebel, Dennis, Wenzel, Joerg, Bieber, Thomas

    “…Neutrophilic dermatosis of the dorsal hands (NDDH) is considered a localized variant of acute febrile neutrophilic dermatosis. It is a rare condition and…”
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    Spleen tyrosine kinase (SYK) is a potential target for the treatment of cutaneous lupus erythematosus patients by Braegelmann, Christine, Hölzel, Michael, Ludbrook, Valerie, Dickson, Marion, Turan, Nil, Ferring-Schmitt, Sandra, Sternberg, Sonja, Bieber, Thomas, Kuhn, Annegret, Wenzel, Joerg

    Published in Experimental dermatology (01-05-2016)
    “…Spleen tyrosine kinase (SYK) is a protein kinase involved in cell proliferation and the regulation of inflammatory pathways. Due to the increasing evidence…”
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