Search Results - "Brady, R H"

Leukocytes, cell adhesion molecules and ischemic acute renal failure by Rabb, Hamid, O'Meara, Yvonne M., Maderna, Paola, Coleman, Patrick, Brady, Hugh R.

“…Leukocytes, cell adhesion molecules and ischemic acute renal failure. Ischemic acute renal failure (ARF) is a common clinical syndrome, associated with high…”
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Connective tissue growth factor: Potential role in glomerulosclerosis and tubulointerstitial fibrosis by Gupta, Sunil, Clarkson, Michael R., Duggan, Joseph, Brady, Hugh R.

“…Connective tissue growth factor: Potential role in glomerulosclerosis and tubulointerstitial fibrosis. Transforming growth factor beta (TGF-β) is a pivotal…”
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Leukocyte adhesion molecules and kidney diseases by Brady, Hugh R.

“…Phagocytic leukocytes, particularly neutrophils and monocytes, are important effectors of injury in many forms of glomerulonephritis, vasculitis,…”
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Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells by Papayianni, A, Serhan, CN, Brady, HR

“…Lipoxins are bioactive eicosanoids that are generated within the vascular lumen by leukocytes and transcellular biosynthetic routes during multicellular…”
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Acute renal failure by Brady, H R, Singer, G G

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Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization by Crean, John K., Furlong, Fiona, Finlay, Darren, Mitchell, Derick, Conway, Bryan, Brady, Hugh R., Godson, Catherine, Martin, Finian

“…ABSTRACT Connective tissue growth factor [CTGF]/CCN2 is a prototypic member of the CCN family of regulatory proteins. CTGF expression is up‐regulated in a…”
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Neutrophil apoptosis is delayed in patients with inflammatory bowel disease by Brannigan, A E, O'Connell, P R, Hurley, H, O'Neill, A, Brady, H R, Fitzpatrick, J M, Watson, R W

“…Delayed neutrophil apoptosis is a feature of persistent acute inflammation. Neutrophil-mediated damage has been shown to be associated with the development of…”
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Fibrillary glomerulopathy by Brady, Hugh R., Cohen, Jordan J., Harrington, John T.

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Common polymorphisms of the PAI1 gene do not play a major role in the development of diabetic nephropathy in Type 1 diabetes by Martin, R. J. L., Savage, D. A., Patterson, C. C., Brady, H. R., Maxwell, A. P.

“…Aim  Plasminogen activator inhibitor 1 (PAI1) plays a key role in the regulation of extracellular matrix (ECM) degradation. The PAI1 gene is therefore an…”
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Clinical features, predictors of disease progression and results of renal transplantation in fibrillary/immunotactoid glomerulopathy by PRONOVOST, P. H, BRADY, H. R, GUNNING, M. E, ESPINOZA, O, RENNKE, H. G

“…The clinical manifestations of fibrillary-immunotactoid glomerulopathy are still being appreciated. It is unclear whether fibrillary-immunotactoid…”
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Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids by Hebert, MJ, Takano, T, Holthofer, H, Brady, HR

“…Dual-laser flow cytometry, based on the properties of the DNA-binding dyes Hoechst 33342 and propidium iodide, was used, with light and electron microscopy and…”
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Circulating vascular cell adhesion molecule–1 in pre-eclampsia, gestational hypertension, and normal pregnancy: Evidence of selective dysregulation of vascular cell adhesion molecule–1 homeostasis in pre-eclampsia by Higgins, John R., Papayianni, Aikaterina, Brady, Hugh R., Darling, Michael R.N., Walshe, Joseph J.

“…OBJECTIVE: Our purpose was to investigate circulating levels of vascular cell adhesion molecule–1 in the peripheral and uteroplacental circulations during…”
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Therapeutic plasma exchange in renal diseases by Madore, F, Lazarus, J M, Brady, H R

“…Plasma exchange has been used extensively for over 2 1/2 decades to treat a variety of renal diseases. In this article, the scientific rationale for…”
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Cell adhesion molecules and the glomerulopathies by Adler, S, Brady, H R

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Thiol‐mediated apoptosis in prostate carcinoma cells by Coffey, Ronan N. T., Watson, R. William G., Hegarty, Nicholas J., O'Neill, Amanda, Gibbons, Norma, Brady, Hugh R., Fitzpatrick, John M.

“…BACKGROUND Glutathione (GSH) maintains an optimum cellular redox potential. Chemical depletion, physical efflux from the cell, or intracellular redistribution…”
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Mitochondrial injury: an early event in cisplatin toxicity to renal proximal tubules by Brady, H R, Kone, B C, Stromski, M E, Zeidel, M L, Giebisch, G, Gullans, S R

“…Oxygen consumption (QO2) and net K+ transport were studied in rabbit proximal tubule suspensions to define the early effects of cisplatin on proximal tubule…”
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Acute nephrotoxic serum nephritis in complement knockout mice : relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria by HEBERT, M.-J, TAKANO, T, PAPAYIANNI, A, RENNKE, H. G, MINTO, A, SALANT, D. J, CARROLL, M. C, BRADY, H. R

“…The importance of complement in the pathophysiology of renal disease is still being appreciated. To further address the role of this mediator system, we…”
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Characterization of a murine model of recurrent herpes simplex viral keratitis induced by ultraviolet B radiation by Laycock, KA, Lee, SF, Brady, RH, Pepose, JS

“…The authors characterized a murine model of herpes simplex virus (HSV) reactivation in which recurrent herpetic keratitis was obtained in up to 80% of animals…”
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15-Hydroxyeicosatetraenoic acid inhibits neutrophil migration across cytokine-activated endothelium by Takata, S, Papayianni, A, Matsubara, M, Jimenez, W, Pronovost, PH, Brady, HR

“…15-hydroxyeicosatetraenoic acid (15-HETE) is an eicosanoid, formed by the actions of 15-lipoxygenase, epoxygenases, and cyclooxygenases on arachidonic acid,…”
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Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis by O'Neill, S, O'Neill, A J, Conroy, E, Brady, H R, Fitzpatrick, J M, Watson, R W

“…Acute pancreatitis (AP) may lead to the development of multiple organ dysfunction syndrome (MODS), especially in severe cases. Resolution of such inflammatory…”
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