Search Results - "Bradrick, Shelton"

Biochemistry and Molecular Biology of Flaviviruses by Barrows, Nicholas J, Campos, Rafael K, Liao, Kuo-Chieh, Prasanth, K. Reddisiva, Soto-Acosta, Ruben, Yeh, Shih-Chia, Schott-Lerner, Geraldine, Pompon, Julien, Sessions, October M, Bradrick, Shelton S, Garcia-Blanco, Mariano A

“…Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile, yellow fever, and Zika viruses, are critically important human…”
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The 5' and 3' Untranslated Regions of the Flaviviral Genome by Ng, Wy Ching, Soto-Acosta, Ruben, Bradrick, Shelton S, Garcia-Blanco, Mariano A, Ooi, Eng Eong

“…Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense RNA genome that can cause serious illness in humans and animals. The…”
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A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection by Barrows, Nicholas J., Campos, Rafael K., Powell, Steven T., Prasanth, K. Reddisiva, Schott-Lerner, Geraldine, Soto-Acosta, Ruben, Galarza-Muñoz, Gaddiel, McGrath, Erica L., Urrabaz-Garza, Rheanna, Gao, Junling, Wu, Ping, Menon, Ramkumar, Saade, George, Fernandez-Salas, Ildefonso, Rossi, Shannan L., Vasilakis, Nikos, Routh, Andrew, Bradrick, Shelton S., Garcia-Blanco, Mariano A.

“…Currently there are no approved vaccines or specific therapies to prevent or treat Zika virus (ZIKV) infection. We interrogated a library of FDA-approved drugs…”
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Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission by Pompon, Julien, Manuel, Menchie, Ng, Geok Kee, Wong, Benjamin, Shan, Chao, Manokaran, Gayathri, Soto-Acosta, Ruben, Bradrick, Shelton S, Ooi, Eng Eong, Missé, Dorothée, Shi, Pei-Yong, Garcia-Blanco, Mariano A

“…Globally re-emerging dengue viruses are transmitted from human-to-human by Aedes mosquitoes. While viral determinants of human pathogenicity have been defined,…”
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Causes and Consequences of Flavivirus RNA Methylation by Bradrick, Shelton S

“…Mosquito-borne flaviviruses are important human pathogens that represent global threats to human health. The genomes of these positive-strand RNA viruses have…”
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RPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein Accumulation by Campos, Rafael K, Wong, Benjamin, Xie, Xuping, Lu, Yi-Fan, Shi, Pei-Yong, Pompon, Julien, Garcia-Blanco, Mariano A, Bradrick, Shelton S

“…The Flavivirus genus contains several arthropod-borne viruses that pose global health threats, including dengue viruses (DENV), yellow fever virus (YFV), and…”
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Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network by Aliota, Matthew T., Bassit, Leda, Bradrick, Shelton S., Cox, Bryan, Garcia-Blanco, Mariano A., Gavegnano, Christina, Friedrich, Thomas C., Golos, Thaddeus G., Griffin, Diane E., Haddow, Andrew D., Kallas, Esper G., Kitron, Uriel, Lecuit, Marc, Magnani, Diogo M., Marrs, Caroline, Mercer, Natalia, McSweegan, Edward, Ng, Lisa F.P., O'Connor, David H., Osorio, Jorge E., Ribeiro, Guilherme S., Ricciardi, Michael, Rossi, Shannan L., Saade, George, Schinazi, Raymond F., Schott-Lerner, Geraldine O., Shan, Chao, Shi, Pei-Yong, Watkins, David I., Vasilakis, Nikos, Weaver, Scott C.

“…In response to the outbreak of Zika virus (ZIKV) infection in the Western Hemisphere and the recognition of a causal association with fetal malformations, the…”
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Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity by Johnson, Bryan A, Hage, Adam, Kalveram, Birte, Mears, Megan, Plante, Jessica A, Rodriguez, Sergio E, Ding, Zhixia, Luo, Xuemei, Bente, Dennis, Bradrick, Shelton S, Freiberg, Alexander N, Popov, Vsevolod, Rajsbaum, Ricardo, Rossi, Shannan, Russell, William K, Menachery, Vineet D

“…Enteric viruses exploit bacterial components, including lipopolysaccharides (LPS) and peptidoglycan (PG), to facilitate infection in humans. Because of their…”
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Regulation of Eukaryotic Initiation Factor 4E (eIF4E) Phosphorylation by Mitogen-Activated Protein Kinase Occurs through Modulation of Mnk1-eIF4G Interaction by Shveygert, Mayya, Kaiser, Constanze, Bradrick, Shelton S., Gromeier, Matthias

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability by Moon, Stephanie L, Blackinton, Jeffrey G, Anderson, John R, Dozier, Mary K, Dodd, Benjamin J T, Keene, Jack D, Wilusz, Carol J, Bradrick, Shelton S, Wilusz, Jeffrey

“…We demonstrate that both Hepatitis C virus (HCV) and Bovine Viral Diarrhea virus (BVDV) contain regions in their 5' UTRs that stall and repress the enzymatic…”
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IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C by Urban, Thomas J., Thompson, Alexander J., Bradrick, Shelton S., Fellay, Jacques, Schuppan, Detlef, Cronin, Kenneth D., Hong, Linda, McKenzie, Alexander, Patel, Keyur, Shianna, Kevin V., McHutchison, John G., Goldstein, David B., Afdhal, Nezam

“…Genetic variation in the IL28B (interleukin 28B; interferon lambda 3) region has been associated with sustained virological response (SVR) rates in patients…”
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Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk by Galarza-Muñoz, Gaddiel, Briggs, Farren B.S., Evsyukova, Irina, Schott-Lerner, Geraldine, Kennedy, Edward M., Nyanhete, Tinashe, Wang, Liuyang, Bergamaschi, Laura, Widen, Steven G., Tomaras, Georgia D., Ko, Dennis C., Bradrick, Shelton S., Barcellos, Lisa F., Gregory, Simon G., Garcia-Blanco, Mariano A.

“…Multiple sclerosis (MS) is an autoimmune disorder where T cells attack neurons in the central nervous system (CNS) leading to demyelination and neurological…”
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Flavivirus RNA transactions from viral entry to genome replication by Garcia-Blanco, Mariano A., Vasudevan, Subhash G., Bradrick, Shelton S., Nicchitta, Christopher

“…Upon release of the ∼11 kb single-stranded positive polarity dengue virus genomic RNA (gRNA) into the cytoplasm of an infected cell, it serves as the template…”
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Identification of gemin5 as a novel 7-methylguanosine cap-binding protein by Bradrick, Shelton S, Gromeier, Matthias

“…A unique attribute of RNA molecules synthesized by RNA polymerase II is the presence of a 7-methylguanosine (m(7)G) cap structure added co-transcriptionally to…”
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Antisense modulation of IL7R splicing to control sIL7R expression in human CD4 + T cells by Galarza-Muñoz, Gaddiel, Kennedy-Boone, Debbie, Schott, Geraldine, Bradrick, Shelton S, Garcia-Blanco, Mariano A

“…The interleukin 7 receptor ( ) is strongly associated with increased risk to develop multiple sclerosis (MS), an autoimmune disease of the central nervous…”
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G protein-coupled receptor kinase 2 promotes flaviviridae entry and replication by Le Sommer, Caroline, Barrows, Nicholas J, Bradrick, Shelton S, Pearson, James L, Garcia-Blanco, Mariano A

“…Flaviviruses cause a wide range of severe diseases ranging from encephalitis to hemorrhagic fever. Discovery of host factors that regulate the fate of…”
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Role of RNA-binding proteins during the late stages of Flavivirus replication cycle by Diosa-Toro, Mayra, Prasanth, K Reddisiva, Bradrick, Shelton S, Garcia Blanco, Mariano A

“…The genus Flavivirus encompasses several worldwide-distributed arthropod-borne viruses including, dengue virus, Japanese encephalitis virus, West Nile virus,…”
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Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins by Campos, Rafael K, Wijeratne, H R Sagara, Shah, Premal, Garcia-Blanco, Mariano A, Bradrick, Shelton S

“…Abstract The ribosomal stalk proteins, RPLP1 and RPLP2 (RPLP1/2), which form the ancient ribosomal stalk, were discovered decades ago but their functions…”
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Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis by Reid, David W, Campos, Rafael K, Child, Jessica R, Zheng, Tianli, Chan, Kitti Wing Ki, Bradrick, Shelton S, Vasudevan, Subhash G, Garcia-Blanco, Mariano A, Nicchitta, Christopher V

“…A primary question in dengue virus (DENV) biology is the molecular strategy for recruitment of host cell protein synthesis machinery. Here, we combined cell…”
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Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA by Soto-Acosta, Ruben, Xie, Xuping, Shan, Chao, Baker, Coleman K, Shi, Pei-Yong, Rossi, Shannan L, Garcia-Blanco, Mariano A, Bradrick, Shelton

“…Subgenomic flaviviral RNA (sfRNA) accumulates during infection due to incomplete degradation of viral genomes and interacts with cellular proteins to promote…”
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