Search Results - "Bradley, Peter J"

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole by Gold, Daniel A., Kaplan, Aaron D., Lis, Agnieszka, Bett, Glenna C.L., Rosowski, Emily E., Cirelli, Kimberly M., Bougdour, Alexandre, Sidik, Saima M., Beck, Josh R., Lourido, Sebastian, Egea, Pascal F., Bradley, Peter J., Hakimi, Mohamed-Ali, Rasmusson, Randall L., Saeij, Jeroen P.J.

“…Toxoplasma gondii is a protozoan pathogen in the phylum Apicomplexa that resides within an intracellular parasitophorous vacuole (PV) that is selectively…”
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BCC0 collaborates with IMC32 and IMC43 to form the Toxoplasma gondii essential daughter bud assembly complex by Pasquarelli, Rebecca R, Sha, Jihui, Wohlschlegel, James A, Bradley, Peter J

“…Toxoplasma gondii divides by endodyogeny, in which two daughter buds are formed within the cytoplasm of the maternal cell using the inner membrane complex…”
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Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway by Quan, Justin J, Nikolov, Lachezar A, Sha, Jihui, Wohlschlegel, James A, Coppens, Isabelle, Bradley, Peter J

“…Toxoplasma gondii resides in its intracellular niche by employing a series of specialized secretory organelles that play roles in invasion, host cell…”
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The Ubiquitin Proteome of Toxoplasma gondii Reveals Roles for Protein Ubiquitination in Cell-Cycle Transitions by Silmon de Monerri, Natalie C., Yakubu, Rama R., Chen, Allan L., Bradley, Peter J., Nieves, Edward, Weiss, Louis M., Kim, Kami

“…Protein ubiquitination plays key roles in protein turnover, cellular signaling, and intracellular transport. The genome of Toxoplasma gondii encodes…”
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Identification of IMC43, a novel IMC protein that collaborates with IMC32 to form an essential daughter bud assembly complex in Toxoplasma gondii by Pasquarelli, Rebecca R, Back, Peter S, Sha, Jihui, Wohlschlegel, James A, Bradley, Peter J

“…The inner membrane complex (IMC) of Toxoplasma gondii is essential for all phases of the parasite's life cycle. One of its most critical roles is to act as a…”
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A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division by Beck, Josh R, Rodriguez-Fernandez, Imilce A, de Leon, Jessica Cruz, Huynh, My-Hang, Carruthers, Vern B, Morrissette, Naomi S, Bradley, Peter J

“…Apicomplexans employ a peripheral membrane system called the inner membrane complex (IMC) for critical processes such as host cell invasion and daughter cell…”
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Novel components of the Toxoplasma inner membrane complex revealed by BioID by Chen, Allan L, Kim, Elliot W, Toh, Justin Y, Vashisht, Ajay A, Rashoff, Andrew Q, Van, Christina, Huang, Amy S, Moon, Andy S, Bell, Hannah N, Bentolila, Laurent A, Wohlschlegel, James A, Bradley, Peter J

“…The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system that is composed of flattened alveolar sacs that underlie the plasma…”
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RON5 is critical for organization and function of the Toxoplasma moving junction complex by Beck, Josh R, Chen, Allan L, Kim, Elliot W, Bradley, Peter J

“…Apicomplexans facilitate host cell invasion through formation of a tight-junction interface between parasite and host plasma membranes called the moving…”
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Characterization and functional analysis of Toxoplasma Golgi-associated proteins identified by proximity labeling by Pasquarelli, Rebecca R, Quan, Justin J, Cheng, Emily S, Yang, Vivian, Britton, Timmie A, Sha, Jihui, Wohlschlegel, James A, Bradley, Peter J

“…possesses a highly polarized secretory pathway that contains both broadly conserved eukaryotic organelles and unique apicomplexan organelles, which play…”
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Multivalent Interactions Drive the Toxoplasma AC9:AC10:ERK7 Complex To Concentrate ERK7 in the Apical Cap by Back, Peter S, O'Shaughnessy, William J, Moon, Andy S, Dewangan, Pravin S, Reese, Michael L, Bradley, Peter J

“…The inner membrane complex (IMC) is a specialized organelle that is crucial for the parasite to establish an intracellular lifestyle and ultimately cause…”
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IMC29 Plays an Important Role in Toxoplasma Endodyogeny and Reveals New Components of the Daughter-Enriched IMC Proteome by Back, Peter S, Moon, Andy S, Pasquarelli, Rebecca R, Bell, Hannah N, Torres, Juan A, Chen, Allan L, Sha, Jihui, Vashisht, Ajay A, Wohlschlegel, James A, Bradley, Peter J

“…The inner membrane complex (IMC) is a unique organelle that plays critical roles in parasite motility, invasion, egress, and replication. The IMC is delineated…”
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Identification and Molecular Dissection of IMC32, a Conserved Toxoplasma Inner Membrane Complex Protein That Is Essential for Parasite Replication by Torres, Juan A, Pasquarelli, Rebecca R, Back, Peter S, Moon, Andy S, Bradley, Peter J

“…The inner membrane complex (IMC) is a unique organelle of apicomplexan parasites that plays critical roles in parasite motility, host cell invasion, and…”
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A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress by Beck, Josh R, Fung, Connie, Straub, Kurtis W, Coppens, Isabelle, Vashisht, Ajay A, Wohlschlegel, James A, Bradley, Peter J

“…Apicomplexans are obligate intracellular parasites that actively penetrate their host cells to create an intracellular niche for replication. Commitment to…”
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A Novel Toxoplasma Inner Membrane Complex Suture-Associated Protein Regulates Suture Protein Targeting and Colocalizes with Membrane Trafficking Machinery by Chern, Jessica H, Pasquarelli, Rebecca R, Moon, Andy S, Chen, Allan L, Sha, Jihui, Wohlschlegel, James A, Bradley, Peter J

“…The cytoskeleton of Toxoplasma gondii is composed of the inner membrane complex (IMC) and an array of underlying microtubules that provide support at the…”
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Novel components of the Apicomplexan moving junction reveal conserved and coccidia‐restricted elements by Straub, Kurtis W., Cheng, Stephen J., Sohn, Catherine S., Bradley, Peter J.

“…Summary Apicomplexan parasites generally invade their host cells by anchoring the parasite to the host membrane through a structure called the moving junction…”
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Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography by Wang, Kevin, Peng, Eric D, Huang, Amy S, Xia, Dong, Vermont, Sarah J, Lentini, Gaelle, Lebrun, Maryse, Wastling, Jonathan M, Bradley, Peter J

“…Toxoplasma gondii maintains its intracellular life cycle using an extraordinary arsenal of parasite-specific organelles including the inner membrane complex…”
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A SAS-6-Like Protein Suggests that the Toxoplasma Conoid Complex Evolved from Flagellar Components by de Leon, Jessica Cruz, Scheumann, Nicole, Beatty, Wandy, Beck, Josh R, Tran, Johnson Q, Yau, Candace, Bradley, Peter J, Gull, Keith, Wickstead, Bill, Morrissette, Naomi S

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Proteomic Analysis of Rhoptry Organelles Reveals Many Novel Constituents for Host-Parasite Interactions in Toxoplasma gondii by Bradley, Peter J., Ward, Chris, Cheng, Stephen J., Alexander, David L., Coller, Susan, Coombs, Graham H., Dunn, Joe Dan, Ferguson, David J., Sanderson, Sanya J., Wastling, Jonathan M., Boothroyd, John C.

“…Rhoptries are specialized secretory organelles that are uniquely present within protozoan parasites of the phylum Apicomplexa. These obligate intracellular…”
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Intervacuolar Transport and Unique Topology of GRA14, a Novel Dense Granule Protein in Toxoplasma gondii by Rome, Michael E, Beck, Josh R, Turetzky, Jay M, Webster, Paul, Bradley, Peter J

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Toxoplasma gondii Targets a Protein Phosphatase 2C to the Nuclei of Infected Host Cells by Gilbert, Luke A, Ravindran, Sandeep, Turetzky, Jay M, Boothroyd, John C, Bradley, Peter J

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