Search Results - "Bradley, Michael E"

Interactions among Prions and Prion "Strains" in Yeast by Bradley, Michael E., Edskes, Herman K., Hong, Joo Y., Wickner, Reed B., Liebman, Susan W.

“…Prions are "infectious" proteins. When Sup35, a yeast translation termination factor, is aggregated in its [PSI+]prion form its function is compromised. When…”
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The Sup35 domains required for maintenance of weak, strong or undifferentiated yeast [PSI+] prions by Bradley, Michael E., Liebman, Susan W.

“…Summary The Sup35 protein can exist in a non‐infectious form or in various infectious forms called [PSI+] prion variants (or prion strains). Each of the…”
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Genetic and Environmental Factors Affecting the de novo Appearance of the [PSI(+)] Prion in Saccharomyces cerevisiae by Derkatch, I. L, Bradley, M. E, Zhou, P, Chernoff, Y. O, Liebman, S. W

“…It has previously been shown that yeast prion [PSI+] is cured by GuHCl, although reports on reversibility of curing were contradictory. Here we show that GuHCl…”
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The role of voltage-gated potassium channels in the regulation of mouse uterine contractility by Smith, Ryan C, McClure, Marisa C, Smith, Margaret A, Abel, Peter W, Bradley, Michael E

“…Uterine smooth muscle cells exhibit ionic currents that appear to be important in the control of uterine contractility, but how these currents might produce…”
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Phylogenomic approaches to common problems encountered in the analysis of low copy repeats: the sulfotransferase 1A gene family example by Bradley, Michael E, Benner, Steven A

“…Blocks of duplicated genomic DNA sequence longer than 1000 base pairs are known as low copy repeats (LCRs). Identified by their sequence similarity, LCRs are…”
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Sequestration of essential proteins causes prion associated toxicity in yeast by Vishveshwara, Namitha, Bradley, Michael E, Liebman, Susan W

“…Prions are infectious, aggregated proteins that cause diseases in mammals but are not normally toxic in fungi. Excess Sup35p, an essential yeast protein that…”
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Integrating protein structures and precomputed genealogies in the Magnum database: examples with cellular retinoid binding proteins by Bradley, Michael E, Benner, Steven A

“…When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein…”
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Prions Affect the Appearance of Other Prions: The Story of [PIN+] by Derkatch, Irina L, Bradley, Michael E, Hong, Joo Y, Liebman, Susan W

“…Prions are self-propagating protein conformations. Recent research brought insight into prion propagation, but how they first appear is unknown. We previously…”
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Nitric oxide relaxes human myometrium by a cGMP-independent mechanism by Bradley, K K, Buxton, I L, Barber, J E, McGaw, T, Bradley, M E

“…The role of intracellular guanosine 3',5'-cyclic monophosphate concentration ([cGMP]i) in nitric oxide (NO)-mediated relaxations in the uterus has become…”
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Overexpression of the SUP45 gene encoding a Sup35p-binding protein inhibits the induction of the de novo appearance of the [PSI+] prion by Derkatch, I.L. (University of Illinois, Chicago, IL.), Bradley, M.E, Liebman, S.W

“…[PSI+], a non-Mendelian element found in some strains of Saccharomyces cerevisiae, is presumed to be the manifestation of a self-propagating prion conformation…”
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Enrico Barone's 'Ministry of Production': Content and Context by Bradley, Michael E., Mosca, Manuela

“…Enrico Barone's famous article on economic planning, 'Il Ministro della Produzione nello Stato Collettivista' ('The Ministry of Production in the Collectivist…”
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Destabilizing Interactions Among [PSI+] and [PIN+] Yeast Prion Variants by Bradley, Michael E, Liebman, Susan W

“…The yeast Sup35 and Rnq1 proteins can exist in either the noninfectious soluble forms, [psi-] or [pin-], respectively, or the multiple infectious amyloid-like…”
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Nitric oxide regulation of monkey myometrial contractility by Kuenzli, Karri A, Buxton, Iain L O, Bradley, Michael E

“…We evaluated the effect of the nitric oxide (NO) donor CysNO (S‐nitroso‐L‐cysteine) and endogenous NO upon spontaneous contractility in non‐pregnant cynomolgus…”
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Sulfate Activation Enzymes: Phylogeny and Association with Pyrophosphatase by Bradley, Michael E, Rest, Joshua S, Li, Wen-Hsiung, Schwartz, Nancy B

“…The enzymes catalyzing the first two reactions in the sulfate activation pathway, ATP-sulfurylase (S) and APS-kinase (K), are fused as 'KS' in animals but are…”
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PERFECT COMPETITION ACCORDING TO ENRICO BARONE by Mosca, Manuela, Bradley, Michael E.

“…The Italian economist Enrico Barone (1859-1924) is best known for his contributions to marginal productivity theory and the socialist planning debate. This…”
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Dependence and independence of [PSI+] and [PIN+]: a two-prion system in yeast? by Derkatch, I.L, Bradley, M.E, Masse, S.V.L, Zadorsky, S.P, Polozkov, G.V, Inge-Vechtomov, S.G, Liebman, S.W

“…The [PSI+] prion can be induced by overproduction of the complete Sup35 protein, but only in strains carrying the non‐Mendelian [PIN+] determinant. Here we…”
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Perfect competition according to Enrico Barone by Mosca, Manuela, Bradley, Michael E

“…L’économiste italien Enrico Barone (1859-1924) est principalement connu pour ses contributions à la théorie de la productivité marginale et au débat sur la…”
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Guanidine reduces stop codon read‐through caused by missense mutations in SUP35 or SUP45 by Bradley, Michael E., Bagriantsev, Sviatoslav, Vishveshwara, Namitha, Liebman, Susan W.

“…Sup35 and Sup45 are essential protein components of the Saccharomyces cerevisiae translation termination factor. Yeast cells harbouring the [PSI+] prion form…”
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Chemotactic, mitogenic, and angiogenic actions of UTP on vascular endothelial cells by Satterwhite, C M, Farrelly, A M, Bradley, M E

“…Endothelial cells express receptors for ATP and UTP, and both UTP and ATP elicit endothelial release of vasoactive compounds such as prostacyclin and nitric…”
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Proteolytic Regulation of the Zinc Finger Transcription Factor YY1, a Repressor of Muscle-restricted Gene Expression by Walowitz, J L, Bradley, M E, Chen, S, Lee, T

“…Regulated proteolysis has been postulated to be critical for proper control of cell functions. Muscle development, in particular, involves a great deal of…”
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