Search Results - "Bradley, Clarrisa A"

PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus by Park, Pojeong, Georgiou, John, Sanderson, Thomas M., Ko, Kwang-Hee, Kang, Heather, Kim, Ji-il, Bradley, Clarrisa A., Bortolotto, Zuner A., Zhuo, Min, Kaang, Bong-Kiun, Collingridge, Graham L.

“…Long-term potentiation (LTP) at hippocampal CA1 synapses can be expressed by an increase either in the number (N) of AMPA…”
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Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons by Faheem, Muhammad, Deneault, Eric, Alexandrova, Roumiana, Rodrigues, Deivid C, Pellecchia, Giovanna, Shum, Carole, Zarrei, Mehdi, Piekna, Alina, Wei, Wei, Howe, Jennifer L, Thiruvahindrapuram, Bhooma, Lamoureux, Sylvia, Ross, P Joel, Bradley, Clarrisa A, Ellis, James, Scherer, Stephen W

“…The X-linked PTCHD1 locus is strongly associated with autism spectrum disorder (ASD). Males who carry chromosome microdeletions of PTCHD1 antisense long…”
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A pivotal role of GSK-3 in synaptic plasticity by Bradley, Clarrisa A, Peineau, Stéphane, Taghibiglou, Changiz, Nicolas, Celine S, Whitcomb, Daniel J, Bortolotto, Zuner A, Kaang, Bong-Kiun, Cho, Kwangwook, Wang, Yu Tian, Collingridge, Graham L

“…Glycogen synthase kinase-3 (GSK-3) has many cellular functions. Recent evidence suggests that it plays a key role in certain types of synaptic plasticity, in…”
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The GSK-3 Inhibitor CT99021 Enhances the Acquisition of Spatial Learning and the Accuracy of Spatial Memory by Lee, Yeseul, Bortolotto, Zuner A, Bradley, Clarrisa A, Sanderson, Thomas M, Zhuo, Min, Kaang, Bong-Kiun, Collingridge, Graham L

“…Glycogen synthase kinase 3 (GSK-3) is a Ser/Thr protein kinase that regulates many cellular processes, including synaptic plasticity. Previously, we reported…”
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Specific Role for GSK3α in Limiting Long-Term Potentiation in CA1 Pyramidal Neurons of Adult Mouse Hippocampus by Ebrahim Amini, Aeen, Miyata, Tsukiko, Lei, Gang, Jin, Fuzi, Rubie, Elizabeth, Bradley, Clarrisa A., Woodgett, James R., Collingridge, Graham L., Georgiou, John

“…Glycogen synthase kinase-3 (GSK3) mediates phosphorylation of several hundred proteins, and its aberrant activity is associated with an array of prevalent…”
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The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface Expression by Sanderson, Thomas M., Bradley, Clarrisa A., Georgiou, John, Hong, Yun Hwa, Ng, Ai Na, Lee, Yeseul, Kim, Hee-Dae, Kim, Doyeon, Amici, Mascia, Son, Gi Hoon, Zhuo, Min, Kim, Kyungjin, Kaang, Bong-Kiun, Kim, Sang Jeong, Collingridge, Graham L.

“…A major mechanism contributing to synaptic plasticity involves alterations in the number of AMPA receptors (AMPARs) expressed at synapses. Hippocampal CA1…”
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A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder by Loureiro, Livia O., Howe, Jennifer L., Reuter, Miriam S., Iaboni, Alana, Calli, Kristina, Roshandel, Delnaz, Pritišanac, Iva, Moses, Alan, Forman-Kay, Julie D., Trost, Brett, Zarrei, Mehdi, Rennie, Olivia, Lau, Lynette Y. S., Marshall, Christian R., Srivastava, Siddharth, Godlewski, Brianna, Buttermore, Elizabeth D., Sahin, Mustafa, Hartley, Dean, Frazier, Thomas, Vorstman, Jacob, Georgiades, Stelios, Lewis, Suzanne M. E., Szatmari, Peter, Bradley, Clarrisa A. (Lisa), Tabet, Anne-Claude, Willems, Marjolaine, Lumbroso, Serge, Piton, Amélie, Lespinasse, James, Delorme, Richard, Bourgeron, Thomas, Anagnostou, Evdokia, Scherer, Stephen W.

“…Autism Spectrum Disorder (ASD) is genetically complex with ~100 copy number variants and genes involved. To try to establish more definitive genotype and…”
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Mechanisms Involved in the Reduction of GABAA Receptor α1-Subunit Expression Caused by the Epilepsy Mutation A322D in the Trafficking-competent Receptor by Bradley, Clarrisa A., Taghibiglou, Changiz, Collingridge, Graham L., Wang, Yu Tian

“…A mutation in the α1-subunit (A322D) of GABAARs is responsible for juvenile myoclonic epilepsy in a large Canadian family. Previous work has identified that…”
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GSK‐3β regulates the synaptic expression of NMDA receptors via phosphorylation of phosphatidylinositol 4 kinase type IIα by Amici, Mascia, Lee, Yeseul, Pope, Robert J. P., Bradley, Clarrisa A., Cole, Adam, Collingridge, Graham L.

“…Deregulation of GSK‐3β is strongly implicated in a variety of serious brain conditions, such as Alzheimer disease, bipolar disorder and schizophrenia. To…”
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PI3Kγ is required for NMDA receptor-dependent long-term depression and behavioral flexibility by Kaang, Bong-Kiun, Kim, Jae-Ick, Lee, Hye-Ryeon, Sim, Su-eon, Baek, Jinhee, Yu, Nam-Kyung, Choi, Jun-Hyeok, Ko, Hyoung-Gon, Lee, Yong-Seok, Park, Soo-Won, Kwak, Chuljung, Ahn, Sung-Ji, Choi, So Yoen, Kim, Hyun, Kim, Kyoung-Han, Backx, Peter H, Bradley, Clarrisa A, Kim, Eunjoon, Jang, Deok-Jin, Lee, Kyungmin, Kim, Sang Jeong, Zhuo, Min, Collingridge, Graham L

“…This study examines the contribution of a specific phosphatidylinositol 3-kinase (PI3K) isoform, namely PI3Kγ, to hippocampal synaptic plasticity and behavior…”
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Exorhodopsin and melanopsin systems in the pineal complex and brain at early developmental stages of Atlantic halibut (Hippoglossus hippoglossus) by Eilertsen, Mariann, Drivenes, Øyvind, Edvardsen, Rolf B., Bradley, Clarrisa A., Ebbesson, Lars O.E., Helvik, Jon Vidar

“…ABSTRACT The complexity of the nonvisual photoreception systems in teleosts has just started to be appreciated, with colocalization of multiple photoreceptor…”
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Mechanisms involved in cholesterol-induced neuronal insulin resistance by Taghibiglou, Changiz, Bradley, Clarrisa A., Gaertner, Tara, Li, Yuping, Wang, Yushan, Wang, Yu Tian

“…Insulin receptors (IRs) are highly expressed in the central nervous system (CNS) and play an important role in normal brain functions, such as learning and…”
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Genomic architecture of autism from comprehensive whole-genome sequence annotation by Trost, Brett, Thiruvahindrapuram, Bhooma, Chan, Ada J.S., Engchuan, Worrawat, Higginbotham, Edward J., Howe, Jennifer L., Loureiro, Livia O., Reuter, Miriam S., Roshandel, Delnaz, Whitney, Joe, Zarrei, Mehdi, Bookman, Matthew, Somerville, Cherith, Shaath, Rulan, Abdi, Mona, Aliyev, Elbay, Patel, Rohan V., Pellecchia, Giovanna, Hamdan, Omar, Kaur, Gaganjot, Wang, Zhuozhi, MacDonald, Jeffrey R., Wei, John, Sung, Wilson W.L., Lamoureux, Sylvia, Hoang, Ny, Selvanayagam, Thanuja, Deflaux, Nicole, Geng, Melissa, Ghaffari, Siavash, Bates, John, Young, Edwin J., Ding, Qiliang, Shum, Carole, D'Abate, Lia, Bradley, Clarrisa A., Rutherford, Annabel, Aguda, Vernie, Apresto, Beverly, Chen, Nan, Desai, Sachin, Du, Xiaoyan, Fong, Matthew L.Y., Pullenayegum, Sanjeev, Samler, Kozue, Wang, Ting, Ho, Karen, Paton, Tara, Pereira, Sergio L., Herbrick, Jo-Anne, Fuerth, Jonathan, Noppornpitak, Juti, Ward, Heather, Magee, Patrick, Al Baz, Ayman, Kajendirarajah, Usanthan, Vlasblom, Jim, Valluri, Monica, Green, Joseph, Seifer, Vicki, Quirbach, Morgan, Rennie, Olivia, Kelley, Elizabeth, Masjedi, Nina, Lord, Catherine, Szego, Michael J., Zawati, Ma'n H., Lang, Michael, Strug, Lisa J., Marshall, Christian R., Costain, Gregory, Calli, Kristina, Iaboni, Alana, Yusuf, Afiqah, Ambrozewicz, Patricia, Gallagher, Louise, Amaral, David G., Brian, Jessica, Elsabbagh, Mayada, Georgiades, Stelios, Messinger, Daniel S., Ozonoff, Sally, Sebat, Jonathan, Sjaarda, Calvin, Smith, Isabel M., Szatmari, Peter, Zwaigenbaum, Lonnie, Kushki, Azadeh, Frazier, Thomas W., Vorstman, Jacob A.S., Fakhro, Khalid A., Fernandez, Bridget A., Lewis, M.E. Suzanne, Weksberg, Rosanna, Fiume, Marc, Yuen, Ryan K.C., Anagnostou, Evdokia, Sondheimer, Neal, Glazer, David, Hartley, Dean M.

“…Fully understanding autism spectrum disorder (ASD) genetics requires whole-genome sequencing (WGS). We present the latest release of the Autism Speaks MSSNG…”
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Mechanisms Involved in the Reduction of GABAA Receptor α1-Subunit Expression Caused by the Epilepsy Mutation A322D in the Trafficking-competent Receptor by Clarrisa A. Bradley, Changiz Taghibiglou, Graham L. Collingridge, Yu Tian Wang

“…A mutation in the α1-subunit (A322D) of GABA A Rs is responsible for juvenile myoclonic epilepsy in a large Canadian family. Previous work has identified that…”
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Mechanisms involved in the reduction of GABAA receptor alpha1-subunit expression caused by the epilepsy mutation A322D in the trafficking-competent receptor by Bradley, Clarrisa A, Taghibiglou, Changiz, Collingridge, Graham L, Wang, Yu Tian

“…A mutation in the alpha1-subunit (A322D) of GABA(A)Rs is responsible for juvenile myoclonic epilepsy in a large Canadian family. Previous work has identified…”
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PI3K[gamma] is required for NMDA receptor-dependent long-term depression and behavioral flexibility by Kim, Jae-ick, Lee, Hye-ryeon, Sim, Su-eon, Baek, Jinhee, Yu, Nam-kyung, Choi, Jun-hyeok, Ko, Hyoung-gon, Lee, Yong-seok, Park, Soo-won, Kwak, Chuljung, Ahn, Sung-ji, Choi, So Yoen, Kim, Hyun, Kim, Kyoung-han, Backx, Peter H, Bradley, Clarrisa A, Kim, Eunjoon, Jang, Deok-jin, Lee, Kyungmin, Kim, Sang Jeong, Zhuo, Min, Collingridge, Graham L, Kaang, Bong-kiun

“…Phosphatidylinositol 3-kinase (PI3K) has been implicated in synaptic plasticity and other neural functions in the brain. However, the role of individual PI3K…”
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