Search Results - "Brad W. Warner"

Enterically derived high-density lipoprotein restrains liver injury through the portal vein by Han, Yong-Hyun, Onufer, Emily J, Huang, Li-Hao, Sprung, Robert W, Davidson, W Sean, Czepielewski, Rafael S, Wohltmann, Mary, Sorci-Thomas, Mary G, Warner, Brad W, Randolph, Gwendalyn J

“…The biogenesis of high-density lipoprotein (HDL) requires apoA1 and the cholesterol transporter ABCA1. Although the liver generates most of the HDL in the…”
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Intestinal Rehabilitation Programs in the Management of Pediatric Intestinal Failure and Short Bowel Syndrome by Merritt, Russell J., Cohran, Valeria, Raphael, Bram P., Sentongo, Timothy, Volpert, Diana, Warner, Brad W., Goday, Praveen S.

“…ABSTRACT Intestinal failure is a rare, debilitating condition that presents both acute and chronic medical management challenges. The condition is incompatible…”
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Nutrition in Necrotizing Enterocolitis and Following Intestinal Resection by Ou, Jocelyn, Courtney, Cathleen M, Steinberger, Allie E, Tecos, Maria E, Warner, Brad W

“…This review aims to discuss the role of nutrition and feeding practices in necrotizing enterocolitis (NEC), NEC prevention, and its complications, including…”
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The Pathogenesis of Resection-Associated Intestinal Adaptation by Warner, Brad W

“…After massive small-bowel resection, the remnant bowel compensates by a process termed adaptation . Adaptation is characterized by villus elongation and crypt…”
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De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders by Qi, Hongjian, Yu, Lan, Zhou, Xueya, Wynn, Julia, Zhao, Haoquan, Guo, Yicheng, Zhu, Na, Kitaygorodsky, Alexander, Hernan, Rebecca, Aspelund, Gudrun, Lim, Foong-Yen, Crombleholme, Timothy, Cusick, Robert, Azarow, Kenneth, Danko, Melissa E, Chung, Dai, Warner, Brad W, Mychaliska, George B, Potoka, Douglas, Wagner, Amy J, ElFiky, Mahmoud, Wilson, Jay M, Nickerson, Debbie, Bamshad, Michael, High, Frances A, Longoni, Mauro, Donahoe, Patricia K, Chung, Wendy K, Shen, Yufeng

“…Congenital diaphragmatic hernia (CDH) is a severe birth defect that is often accompanied by other congenital anomalies. Previous exome sequencing studies for…”
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Lipid absorption and overall intestinal lymphatic transport are impaired following partial small bowel resection in mice by Onufer, Emily J., Czepielewski, Rafael S., Han, Yong-Hyun, Courtney, Cathleen M., Sutton, Stephanie, Sescleifer, Anne, Randolph, Gwendalyn J., Warner, Brad W.

“…Short bowel syndrome (SBS) is associated with diminished levels of serum fats caused by unknown mechanisms. We have shown that mesenteric lymphatics remodel to…”
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Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF) by He, Yonghua, Schmidt, Monica A, Erwin, Christopher, Guo, Jun, Sun, Raphael, Pendarvis, Ken, Warner, Brad W, Herman, Eliot M

“…Necrotizing enterocolitis (NEC) is a devastating condition of premature infants that results from the gut microbiome invading immature intestinal tissues. This…”
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Impact of hospital volume on in-hospital mortality of infants undergoing repair of congenital diaphragmatic hernia by Bucher, Brian T, Guth, Rebecca M, Saito, Jacqueline M, Najaf, Tasnim, Warner, Brad W

“…Congenital diaphragmatic hernia (CDH) remains a significant cause of neonatal morbidity and mortality. Previous studies have suggested that hospital volume is…”
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Comparative outcomes of right versus left congenital diaphragmatic hernia: A multicenter analysis by Abramov, Alexey, Fan, Weijia, Hernan, Rebecca, Zenilman, Ariela L., Wynn, Julia, Aspelund, Gudrun, Khlevner, Julie, Krishnan, Usha, Lim, Foong-Yen, Mychaliska, George B., Warner, Brad W., Cusick, Robert, Crombleholme, Timothy, Chung, Dai, Danko, Melissa E., Wagner, Amy J., Azarow, Kenneth, Schindel, David, Potoka, Douglas, Soffer, Sam, Fisher, Jason, McCulley, David, Farkouh-Karoleski, Christiana, Chung, Wendy K., Duron, Vincent

“…Congenital diaphragmatic hernia (CDH) occurs in 1 out of 2500–3000 live births. Right-sided CDHs (R-CDHs) comprise 25% of all CDH cases, and data are…”
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Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine by Aladegbami, Bola, Barron, Lauren, Bao, James, Colasanti, Jason, Erwin, Christopher R., Warner, Brad W., Guo, Jun

“…Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to…”
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Toll-like receptor 4 is critical for the development of resection-associated hepatic steatosis by Barron, Lauren K., Bao, James W., Aladegbami, Bola G., Colasanti, Jason J., Guo, Jun, Erwin, Christopher R., Warner, Brad W.

“…A significant number of children with short bowel syndrome experience intestinal failure-associated liver disease. We recently demonstrated accelerated hepatic…”
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EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis by Onufer, Emily J., Aladegbami, Bola, Imai, Toru, Seiler, Kristen, Bajinting, Adam, Courtney, Cathleen, Sutton, Stephanie, Bustos, Aiza, Yao, Junjie, Yeh, Cheng-Hung, Sescleifer, Anne, Wang, Lihong V., Guo, Jun, Warner, Brad W.

“…Background Short bowel syndrome (SBS) results from significant loss of small intestinal length. In response to this loss, adaptation occurs, with Epidermal…”
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Variants in GATA4 are a rare cause of familial and sporadic congenital diaphragmatic hernia by Yu, Lan, Wynn, Julia, Cheung, Yee Him, Shen, Yufeng, Mychaliska, George B., Crombleholme, Timothy M., Azarow, Kenneth S., Lim, Foong Yen, Chung, Dai H., Potoka, Douglas, Warner, Brad W., Bucher, Brian, Stolar, Charles, Aspelund, Gudrun, Arkovitz, Marc S., Chung, Wendy K.

“…Congenital diaphragmatic hernia (CDH) is characterized by incomplete formation of the diaphragm occurring as either an isolated defect or in association with…”
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Retinoblastoma Protein (pRb), but Not p107 or p130, Is Required for Maintenance of Enterocyte Quiescence and Differentiation in Small Intestine by Guo, Jun, Longshore, Shannon, Nair, Rajalakshmi, Warner, Brad W.

“…The function of retinoblastoma protein (pRb) in the regulation of small intestine epithelial cell homeostasis has been challenged by several groups using…”
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A Novel Approach to Calculating Small Intestine Length Based on Magnetic Resonance Enterography by Wilson, Nicole A., PhD, MD, Park, Hyung-Soon, PhD, Lee, Kyoung Soub, MS, Barron, Lauren K., MD, Warner, Brad W., MD, FACS

“…Background Bowel length is an important factor in the management of patients with intestinal failure and short bowel syndrome (SBS). However, it is difficult…”
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Antibiotic-driven intestinal dysbiosis in pediatric short bowel syndrome is associated with persistently altered microbiome functions and gut-derived bloodstream infections by Thänert, Robert, Thänert, Anna, Ou, Jocelyn, Bajinting, Adam, Burnham, Carey-Ann D., Engelstad, Holly J., Tecos, Maria E., Ndao, I. Malick, Hall-Moore, Carla, Rouggly-Nickless, Colleen, Carl, Mike A., Rubin, Deborah C., Davidson, Nicholas O., Tarr, Phillip I., Warner, Barbara B., Dantas, Gautam, Warner, Brad W.

“…Surgical removal of the intestine, lifesaving in catastrophic gastrointestinal disorders of infancy, can result in a form of intestinal failure known as short…”
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Liver steatosis induced by small bowel resection is prevented by oral vancomycin by Barron, Lauren K., MD, Gayer, Christopher P., MD, PhD, Roberts, Anne, MD, Golden, Jamie M., MD, Aladegbami, Bola G., MD, Guo, Jun, PhD, Erwin, Christopher R., PhD, Warner, Brad W., MD

“…Background Intestinal failure–associated liver disease causes significant mortality in patients with short bowel syndrome. Steatosis, a major component of…”
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Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis by Wakeman, Derek, MD, Schneider, John E., BS, Liu, Jingxia, PhD, Wandu, Wambul S., BS, Erwin, Christopher R., PhD, Guo, Jun, PhD, Stappenbeck, Thaddeus S., MD, PhD, Warner, Brad W., MD

“…Background p38-Alpha mitogen-activated protein kinase (p38-MAPK) is a tumor suppressor often mutated in human cancers, but its specific role in colorectal…”
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The role of growth factors in intestinal regeneration and repair in necrotizing enterocolitis by Rowland, Kathryn J., MD, Choi, Pamela M., MD, Warner, Brad W., MD

“…Abstract Necrotizing enterocolitis (NEC) is a devastating intestinal disease resulting in major neonatal morbidity and mortality. The pathology is poorly…”
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A Fish Tale Worth Telling: Enteral Fat for Management of Short Gut Syndrome by Warner, Barbara B., MD, Warner, Brad W., MD

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