Search Results - "Brackmann, Hans H"

Frequency of the HIV-protective CC chemokine receptor 5-Δ32/Δ32 genotype is increased in hepatitis C by Woitas, Rainer P., Ahlenstiel, Golo, Iwan, Agathe, Rockstroh, Jürgen K., Brackmann‡, Hans H., Kupfer§, Bernd, Matz§, Bertfried, Offergeld‡, Ruth, Sauerbruch, Tilman, Spengler, Ulrich

“…Background & Aims: A homozygous 32–base pair deletion in the CCR5 gene (CCR5-Δ32) protects against human immunodeficiency virus infection (HIV). However, the…”
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Distribution and effects of polymorphic RANTES gene alleles in HIV/HCV coinfection -- a prospective cross-sectional study by Ahlenstiel, Golo, Iwan, Agathe, Nattermann, Jacob, Bueren, Karin, Rockstroh, Jurgen K, Brackmann, Hans H, Kupfer, Bernd, Landt, Olfert, Peled, Amnon, Sauerbruch, Tilman, Spengler, Ulrich, Woitas, Rainer P

“…Chemokines and their receptors are crucial for immune responses in HCV and HIV infection. RANTES gene polymorphisms lead to altered gene expression and…”
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Human Recombinant DNA–Derived Antihemophilic Factor (Factor VIII) in the Treatment of Hemophilia A by Schwartz, Richard S, Abildgaard, Charles F, Aledort, Louis M, Arkin, Steven, Bloom, Arthur L, Brackmann, Hans H, Brettler, Doreen B, Fukui, Hiromu, Hilgartner, Margaret W, Inwood, Martin J, Kasper, Carol K, Kernoff, Peter B.A, Levine, Peter H, Lusher, Jeanne M, Mannucci, Pier M, Scharrer, Inge, MacKenzie, Mary A, Pancham, Nazreen, Kuo, Harng S, Allred, Randy U

“…HEMOPHILIA A is an X-linked recessive genetic disorder affecting approximately 1 in 10,000 males that is due to a defective or deficient factor VIII molecule,…”
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Lack of F8 mRNA: a novel mechanism leading to hemophilia A by El-Maarri, Osman, Singer, Heike, Klein, Claudia, Watzka, Matthias, Herbiniaux, Ursula, Brackmann, Hans H., Schröder, Jörg, Graw, Jochen, Müller, Clemens R., Schramm, Wolfgang, Schwaab, Rainer, Haaf, Thomas, Hanfland, Peter, Oldenburg, Johannes

“…Hemophilia A (HA) is caused by partial or total deficiency of F8 protein activity. In a small group, about 1.8% of patients with HA, no mutation is found in…”
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Serum antibodies against the hepatitis C virus E2 protein mediate antibody-dependent cellular cytotoxicity (ADCC) by Nattermann, Jacob, Schneiders, Angelika Maria, Leifeld, Ludger, Langhans, Bettina, Schulz, Monika, Inchauspé, Geneviève, Matz, Bertfried, Brackmann, Hans H., Houghton, Michael, Sauerbruch, Tilman, Spengler, Ulrich

“…The role of antibody dependent cellular cytotoxicity (ADCC) in HCV infection is unclear at present. Antibodies mediating ADCC are usually directed against…”
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Effects of the CCR5-Δ32 mutation on antiviral treatment in chronic hepatitis C by Ahlenstiel, Golo, Berg, Thomas, Woitas, Rainer P, Grünhage, Frank, Iwan, Agathe, Heß, Lothar, Brackmann, Hans H, Kupfer, Bernd, Schernick, Andrea, Sauerbruch, Tilman, Spengler, Ulrich

“…Background/Aims: The CC-chemokine receptor (CCR) 5-Δ32 mutation may predispose to chronic liver disease and high level viremia in hepatitis C. However, it is…”
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HCV-specific cytokine induction in monocytes of patients with different outcomes of hepatitis C by Woitas, Rainer P, Petersen, Uwe, Moshage, Dirk, Brackmann, Hans H, Matz, Bertfried, Sauerbruch, Tilman, Spengler, Ulrich

“…Cytokine release by macrophages critically determines the type of immune response to an antigen. Therefore, we studied hepatitis C virus (HCV)-specific…”
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Fifteen years of Env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1 by Kupfer, Bernd, Sing, Tobias, Schüffler, Peter, Hall, Rabea, Kurz, Ralf, McKeown, Astrid, Schneweis, Karl-Eduard, Eberl, Wolfgang, Oldenburg, Johannes, Brackmann, Hans H, Rockstroh, Jürgen K, Spengler, Ulrich, Däumer, Martin P, Kaiser, Rolf, Lengauer, Thomas, Matz, Bertfried

“…The study of the evolution of human immunodeficiency virus type 1 (HIV-1) requires blood samples collected longitudinally and data on the approximate time…”
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Hepatitis C-associated autoimmunity in patients coinfected with HIV by Woitas, Rainer P., Stoschus, Bodo, Terjung, Birgit, Vogel, Martin, Kupfer, Bernd, Brackmann, Hans H., Rockstroh, Jürgen K., Sauerbruch, Tilman, Spengler, Ulrich

“…: Background: Hepatitis C virus (HCV) infection is associated with multiple extrahepatic manifestations. It is unclear to what extent extrahepatic…”
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Comparison of GB virus C, HIV, and HCV infection markers in hemophiliacs exposed to non-inactivated or inactivated factor concentrates by Kupfer, Bernd, Ruf, Torsten, Matz, Bertfried, Nattermann, Jacob, Spengler, Ulrich, Rockstroh, Jürgen K., Brackmann, Hans H., Blümel, Johannes, Tacke, Michael, Kaiser, Rolf

“…Until the mandatory introduction of viral inactivation techniques of blood plasma products in the early 1980s many recipients of these products were infected…”
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Arthroscopy for chronic hemophilic synovitis of the knee by Eickhoff, H H, Koch, W, Raderschadt, G, Brackmann, H H

“…Between 1988 and 1995, 32 knee joints (29 patients) with hemophilic arthropathy underwent arthroscopy. The spectrum of procedures ranged from resection of…”
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Differential expansion of T‐cell receptor variable beta subsets after antigenic stimulation in patients with different outcomes of hepatitis C infection by Woitas, Rainer P., Sippel, Martin, Althausen, Eva‐Maria, Brackmann, Hans H., Kochan, Bettina, Matz, Bertfried, Rockstroh, Jürgen K., Sauerbruch, Tilman, Spengler, Ulrich

“…Summary Persistent antigenic stimulation during chronic hepatitis C may alter the T‐cell receptor variable chain beta (TCR BV) repertoire as well as the…”
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Risk of Hepatitis C After Immunoadsorption by Kaiser, Rolf, Geulen, Oliver, Matz, Bertfried, Brackmann, Hans H., Spengler, Ulrich, Kramer, Michael H., Exner, Martin, Nettekoven, Wilhelm, Ko, You‐Dschun, Zeitler, Heike, Vetter, Hans

“…An episode of acute hepatitis in a patient with hemophilia during immunoadsorption therapy initially was misinterpreted as a reactivated hepatitis C virus…”
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Transient loss of T-cell reactivity in a patient with hepatitis C virus reinfection by Düesberg, U, Geulen, O, Schneiders, A M, Kaiser, R, Brackmann, H H, Matz, B, Sauerbruch, T, Spengler, U

“…Self-limited acute hepatitis C virus (HCV) infection with spontaneous recovery is only rarely observed in clinical practice. All existing studies correlate…”
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A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor by Jacquemin, Marc, Lavend'homme, Renaud, Benhida, Abdellah, Vanzieleghem, Beatrijs, d'Oiron, Roseline, Lavergne, Jean-Maurice, Brackmann, Hans H., Schwaab, Rainer, VandenDriessche, Thierry, Chuah, Marinee K. L., Hoylaerts, Marc, Gilles, Jean Guy G., Peerlinck, Kathelijne, Vermylen, Jos, Saint-Remy, Jean-Marie R.

“…The mechanisms responsible for the low factor VIII (fVIII) activity in the plasma of patients with mild/moderate hemophilia A are poorly understood. In such…”
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Antigen-specific cytokine response to hepatitis C virus core epitopes in HIV/hepatitis C virus-coinfected patients by WOITAS, R. P, ROCKSTROH, J. K, BEIER, I, JUNG, G, KOCHAN, B, MATZ, B, BRACKMANN, H. H, SAUERBRUCH, T, SPENGLER, U

“…Epidemiological data indicate that hepatitis C virus (HCV) infection runs a more rapid and severe course of disease in HIV-coinfected patients, probably…”
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Effects of the CCR5-Delta32 mutation on antiviral treatment in chronic hepatitis C by Ahlenstiel, Golo, Berg, Thomas, Woitas, Rainer P, Grünhage, Frank, Iwan, Agathe, Hess, Lothar, Brackmann, Hans H, Kupfer, Bernd, Schernick, Andrea, Sauerbruch, Tilman, Spengler, Ulrich

“…The CC-chemokine receptor (CCR) 5-Delta32 mutation may predispose to chronic liver disease and high level viremia in hepatitis C. However, it is unclear…”
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The RANTES (-403 G→A) promoter polymorphism does not affect HCV or HIV/HCV co-infection but is increased in HIV infection by Ahlenstiel, Golo, Iwan, Agathe, Rockstroh, Jurgen K., Kupfer, Bernd, Matz, Bertfried, Brackmann, Hans H., Sauerbruch, Tilman, Spengler, Ulrich, Woitas, Rainer P.

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Frequency of the HIV-protective CC chemokine receptor 5-Delta32/Delta32 genotype is increased in hepatitis C by Woitas, Rainer P, Ahlenstiel, Golo, Iwan, Agathe, Rockstroh, Jürgen K, Brackmann, Hans H, Kupfer, Bernd, Matz, Bertfried, Offergeld, Ruth, Sauerbruch, Tilman, Spengler, Ulrich

“…A homozygous 32-base pair deletion in the CCR5 gene (CCR5-Delta32) protects against human immunodeficiency virus infection (HIV). However, the role of this…”
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Hepatitis C virus core antigens induce apoptosis in CD4+ T-lymphocytes by Woitas, Rainer P., Jung, Guenther, Matz, Bertfried, Brackmann, Hans H., Sauerbruch, Tilman, Spengler, Ulrich

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