Search Results - "Brack, Markus C"
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Preclinical Assessment of Bacteriophage Therapy against Experimental Acinetobacter baumannii Lung Infection
Published in Viruses (24-12-2021)“…Respiratory infections caused by multidrug-resistant are difficult to treat and associated with high mortality among critically ill hospitalized patients…”
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Cardiovascular sequelae of pneumonia
Published in Current opinion in pulmonary medicine (01-05-2019)“…PURPOSE OF REVIEWIn this brief review, we discuss the current epidemiological data and latest results from basic research on the cardiovascular sequelae after…”
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Pneumonia Induced Rise in Glucagon Promotes Endothelial Damage and Thrombogenicity
Published in Circulation research (08-11-2024)Get full text
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In Vitro Screening Identifies TRPV4 and PAR1 as Targets for Endothelial Barrier Stabilization in COVID‐19
Published in The FASEB journal (01-05-2022)“…Study objective Endothelial dysfunction and increased microvascular permeability are hallmarks of severe COVID‐19. At present, the underlying mechanisms of…”
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Cystic fibrosis transmembrane conductance regulator modulators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients
Published in The European respiratory journal (01-03-2023)“…Cystic fibrosis transmembrane conductance regulator (CFTR) modulators reduce agonist-induced platelet activation and function. CFTR modulators, such as…”
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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure
Published in The European respiratory journal (05-11-2020)“…Approximately 20% of symptomatic patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection progress to severe coronavirus disease…”
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Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19
Published in Blood advances (08-02-2022)“…The high incidence of thrombotic events suggests a possible role of the contact system pathway in COVID-19 pathology. In this study, we determined the altered…”
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