Search Results - "Bracht, Tobias"
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A review of white matter microstructure alterations of pathways of the reward circuit in depression
Published in Journal of affective disorders (15-11-2015)“…Abstract Background Depressed mood, anhedonia, psychomotor retardation and alterations of circadian rhythm are core features of the depressive syndrome. Its…”
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Increased fractional anisotropy in the motor tracts of Parkinson's disease suggests compensatory neuroplasticity or selective neurodegeneration
Published in European radiology (01-10-2016)“…Objective To determine the differences in motor pathways and selected non-motor pathways of the basal ganglia in Parkinson’s disease (PD) patients compared to…”
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Analyzing fractal dimension in electroconvulsive therapy: Unraveling complexity in structural and functional neuroimaging
Published in NeuroImage (Orlando, Fla.) (15-08-2024)“…•First study to use complexity measures to investigate ECT-effects.•Significant increase of Higuchi's fractal dimension (HFD) following ECT.•Right anterior…”
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Distinct and shared patterns of brain plasticity during electroconvulsive therapy and treatment as usual in depression: an observational multimodal MRI-study
Published in Translational psychiatry (10-01-2023)“…Electroconvulsive therapy (ECT) is a highly effective treatment for depression. Previous studies point to ECT-induced volume increase in the hippocampi and…”
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Link between structural connectivity of the medial forebrain bundle, functional connectivity of the ventral tegmental area, and anhedonia in unipolar depression
Published in NeuroImage clinical (01-01-2022)“…•Tract volume and number of tracts are reduced in the left slMFB.•Those microstructural alterations are related to depression severity and anhedonia.•There is…”
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White matter microstructure alterations of the medial forebrain bundle in melancholic depression
Published in Journal of affective disorders (01-02-2014)“…Abstract Background The medial forebrain bundle (MFB) is a key structure of the reward system and connects the ventral tegmental area (VTA) with the nucleus…”
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The role of the orbitofrontal cortex and the nucleus accumbens for craving in alcohol use disorder
Published in Translational psychiatry (04-05-2021)“…This study aimed to investigate structural and functional alterations of the reward system and the neurobiology of craving in alcohol use disorder (AUD). We…”
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Limbic white matter microstructure plasticity reflects recovery from depression
Published in Journal of affective disorders (01-01-2015)“…Abstract Background White matter microstructure alterations of limbic and reward pathways have been reported repeatedly for depressive episodes in major…”
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White matter pathway organization of the reward system is related to positive and negative symptoms in schizophrenia
Published in Schizophrenia research (01-03-2014)“…Abstract The reward system in schizophrenia has been linked to the emergence of delusions on the one hand and to negative symptoms such as affective flattening…”
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Associations of thalamocortical networks with reduced mindfulness in alcohol use disorder
Published in Frontiers in psychiatry (06-07-2023)“…Increased mindfulness is associated with reduced alcohol consumption in patients with alcohol use disorder (AUD) after residential treatment. However, the…”
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Cortico-cortical white matter motor pathway microstructure is related to psychomotor retardation in major depressive disorder
Published in PloS one (20-12-2012)“…Alterations of brain structure and function have been associated with psychomotor retardation in major depressive disorder (MDD). However, the association of…”
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Frontal white matter integrity is related to psychomotor retardation in major depression
Published in Neurobiology of disease (01-07-2012)“…Abstract Altered frontal white matter integrity has been reported in major depression. Still, the behavioral correlates of these alterations are not…”
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Altered cortico-basal ganglia motor pathways reflect reduced volitional motor activity in schizophrenia
Published in Schizophrenia research (01-02-2013)“…Abstract Little is known about the neurobiology of hypokinesia in schizophrenia. Therefore, the aim of this study was to investigate alterations of white…”
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Electroconvulsive therapy induces remodeling of hippocampal co-activation with the default mode network in patients with depression
Published in NeuroImage clinical (01-01-2023)“…•ECT modifies coupling between the hippocampus and the default mode network.•ECT induces microstructural alterations in the parahippocampal cingulum.•ECT…”
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Physical activity is associated with left corticospinal tract microstructure in bipolar depression
Published in NeuroImage clinical (01-01-2018)“…Psychomotor retardation and reduced daily activities are core features of the depressive syndrome including bipolar disorder (BD). It was the aim of this study…”
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Increased structural connectivity of the medial forebrain bundle in schizophrenia spectrum disorders is associated with delusions of paranoid threat and grandiosity
Published in NeuroImage clinical (01-01-2019)“…•Increased FA of bilateral slMFB can be found in delusional SSD-patients.•Findings are supported by a psychopathological model of paranoia and…”
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Low sleep quality in major depressive disorder is associated with thinning and decreased functional connectivity of the insular cortex
Published in Journal of affective disorders reports (01-04-2024)“…•Sleep disturbances are more pronounced in patients with depression.•Poor sleep quality is associated with thinner insular cortex.•Poor sleep quality is…”
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Increased functional connectivity of amygdalar-frontal pathways in patients with alcohol use disorder and childhood trauma
Published in Neuroimage. Reports (01-12-2024)“…Childhood trauma (CT) often co-occurs with alcohol use disorder (AUD) and is associated with poor treatment outcome. We could demonstrated that patients with…”
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Hippocampal volume and parahippocampal cingulum alterations are associated with avoidant attachment in patients with depression
Published in Journal of affective disorders reports (01-12-2022)“…•Patients with depression have higher attachment avoidance and anxiety.•Depression severity correlates with the extent of avoidant and anxious attachment.•High…”
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Long-Term Outcome and Neuroimaging of Deep Brain Stimulation in Holmes Tremor: A Case Series
Published in Neuromodulation (Malden, Mass.) (01-02-2021)“…Different deep brain stimulation (DBS) targets have been suggested as treatment for patients with pharmacologically refractory Holmes tremor (HT). We report…”
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