Search Results - "Brachmann, C"

A randomized, controlled phase III trial of nab-Paclitaxel versus dacarbazine in chemotherapy-naïve patients with metastatic melanoma by Hersh, E.M., Del Vecchio, M., Brown, M.P., Kefford, R., Loquai, C., Testori, A., Bhatia, S., Gutzmer, R., Conry, R., Haydon, A., Robert, C., Ernst, S., Homsi, J., Grob, J.J., Kendra, K., Agarwala, S.S., Li, M., Clawson, A., Brachmann, C., Karnoub, M., Elias, I., Renschler, M.F., Hauschild, A.

“…The efficacy and safety of nab-paclitaxel versus dacarbazine in patients with metastatic melanoma was evaluated in a phase III randomized, controlled trial…”
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Identification of the death zone: a spatially restricted region for programmed cell death that sculpts the fly eye by Monserrate, J P, Brachmann, C Baker

“…Programmed cell death (PCD) sculpts many developing tissues. The final patterning step of the Drosophila retina is the elimination, through PCD, of a subset of…”
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Results of a phase I study of andecaliximab in combination with mFOLFOX6 and bevacizumab in patients with previously untreated metastatic colorectal cancer by Lenz, H.-J., Park, H., Shah, M.A., Berlin, J.D., Bruetman, D., Chaves, J., Gordon, M., Patel, R., Starodub, A., Liu, J., Baker Brachmann, C., Bhargava, P., Wainberg, Z.A., Bendell, J.

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A Modular Analysis Tool for Imaging-Based Clinical Research in Radiation Therapy by Weiler, F, Chlebus, G, Brachmann, C, Traulsen, N, Waring, A, Rieder, C, Lassen-Schmidt, B, Krass, S, Hahn, H

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PO-1092 A novel, efficient contour mapping method facilitates adaptive radiotherapy in head and neck patients by Nijhuis, R, Brachmann, C, Weiler, F, Traulsen, N, Corr, D, Schenk, M, Ganswindt, U, Thieke, C, Wirtz, S, Belka, C

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The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability by Brachmann, C B, Sherman, J M, Devine, S E, Cameron, E E, Pillus, L, Boeke, J D

“…Genomic silencing is a fundamental mechanism of transcriptional regulation, yet little is known about conserved mechanisms of silencing. We report here the…”
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Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR‐mediated gene disruption and other applications by Baker Brachmann, Carrie, Davies, Adrian, Cost, Gregory J., Caputo, Emerita, Li, Joachim, Hieter, Philip, Boeke, Jef D.

“…A set of yeast strains based on Saccharomyces cerevisiae S288C in which commonly used selectable marker genes are deleted by design based on the yeast genome…”
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A Phylogenetically Conserved NAD+-Dependent Protein Deacetylase Activity in the Sir2 Protein Family by Smith, Jeffrey S., Brachmann, Carrie Baker, Celic, Ivana, Kenna, Margaret A., Muhammad, Shabazz, Starai, Vincent J., Avalos, Jose L., Escalante-Semerena, Jorge C., Grubmeyer, Charles, Wolberger, Cynthia, Boeke, Jef D.

“…The yeast Sir2 protein, required for transcriptional silencing, has an NAD+-dependent histone deacetylase (HDA) activity. Yeast extracts contain a…”
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A critical proteolytic cleavage site near the C terminus of the yeast retrotransposon Ty1 Gag protein by Merkulov, G V, Swiderek, K M, Brachmann, C B, Boeke, J D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Patterning the fly eye: the role of apoptosis by Brachmann, Carrie Baker, Cagan, Ross L

“…Early development in many tissues is characterized by a rapid expansion in cell number. Excess cells are removed through activation of their intrinsic…”
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Delta and notch promote correct localization of irreC-rst by Gorski, S M, Brachmann, C B, Tanenbaum, S B, Cagan, R L

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Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p by Smith, J.S. (Johns Hopkins University School of Medicine, Baltimore, MD.), Brachmann, C.B, Pillus, L, Boeke, J.D

“…Transcriptional silencing in Saccharomyces cerevisiae occurs at the silent mating-type loci HML and HMR, at telomeres, and at the ribosomal DNA (rDNA) locus…”
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The Drosophila Bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation by Brachmann, Carrie Baker, Jassim, Omar W., Wachsmuth, Benjamin D., Cagan, Ross L.

“…As with all metazoans, the fly makes extensive use of selective programmed cell death (PCD) to remove excess cells and properly sculpt developing tissues…”
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The conserved core of a human SIR2 homologue functions in yeast silencing by Sherman, J M, Stone, E M, Freeman-Cook, L L, Brachmann, C B, Boeke, J D, Pillus, L

“…Silencing is a universal form of transcriptional regulation in which regions of the genome are reversibly inactivated by changes in chromatin structure. Sir2…”
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Invading the Yeast Nucleus: a Nuclear Localization Signal at the C Terminus of Ty1 Integrase Is Required for Transposition In Vivo by Kenna, Margaret A., Brachmann, Carrie Baker, Devine, Scott E., Boeke, Jef D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions by Freeman-Cook, L L, Sherman, J M, Brachmann, C B, Allshire, R C, Boeke, J D, Pillus, L

“…Although silencing is a significant form of transcriptional regulation, the functional and mechanistic limits of its conservation have not yet been…”
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Sparc Analysis in the Phase III MPACT Trial of NAB-Paclitaxel (Nab-P) Plus Gemcitabine (GEM) vs GEM Alone for Patients with Metastatic Pancreatic Cancer (PC) by Hidalgo, M., Plaza, C., Illei, P., Brachmann, C., Heise, C., Pierce, D., Romano, A., Wei, X., López-Ríos, F., Von Hoff, D.

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567PResults of a phase I study of andecaliximab in combination with mFOLFOX6 and bevacizumab in patients with previously untreated metastatic colorectal cancer by Lenz, H-J, Park, H, Shah, M A, Berlin, J D, Bruetman, D, Chaves, J, Gordon, M, Patel, R, Starodub, A, Liu, J, Baker Brachmann, C, Bhargava, P, Wainberg, Z A, Bendell, J

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Mapping the multimerization domains of the Gag protein of yeast retrotransposon Ty1 by Brachmann, C B, Boeke, J D

“…The two-hybrid system was used to define regions of the Ty1 Gag protein responsible for multimerization. Gag truncations lacking the first 146 or the last 97…”
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OC-0486: Multi-criterial patient positioning based on dose recalculation on scatter-corrected CBCT images by Hofmaier, J., Haehnle, J., Kurz, C., Landry, G., Maihöfer, C., Süss, P., Teichert, K., Traulsen, N., Brachmann, C., Weiler, F., Thieke, C., Küfer, K.H., Belka, C., Parodi, K., Kamp, F.

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