Search Results - "Brachman, Rebecca A"
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Hippocampal Memory Traces Are Differentially Modulated by Experience, Time, and Adult Neurogenesis
Published in Neuron (Cambridge, Mass.) (02-07-2014)“…Memory traces are believed to be ensembles of cells used to store memories. To visualize memory traces, we created a transgenic line that allows for the…”
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Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine–Induced Sustained Antidepressant-like Effects
Published in Biological psychiatry (1969) (01-07-2018)Get full text
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Ventral CA3 Activation Mediates Prophylactic Ketamine Efficacy Against Stress-Induced Depressive-like Behavior
Published in Biological psychiatry (1969) (01-12-2018)“…We previously reported that a single injection of ketamine prior to stress protects against the onset of depressive-like behavior and attenuates learned fear…”
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Lymphocytes from chronically stressed mice confer antidepressant-like effects to naive mice
Published in The Journal of neuroscience (28-01-2015)“…We examined whether cells of the adaptive immune system retain the memory of psychosocial stress and thereby alter mood states and CNS function in the host…”
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Glucocorticoids orchestrate divergent effects on mood through adult neurogenesis
Published in The Journal of neuroscience (13-02-2013)“…Both social defeat stress and environmental enrichment stimulate adrenal glucocorticoid secretion, but they have opposing effects on hippocampal neurogenesis…”
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Ketamine as a Prophylactic Against Stress-Induced Depressive-Like Behavior
Published in Biological psychiatry (1969) (01-05-2016)“…Abstract Background Stress exposure is one of the greatest risk factors for psychiatric illnesses like major depressive disorder and posttraumatic stress…”
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Prophylactic ketamine alters nucleotide and neurotransmitter metabolism in brain and plasma following stress
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2018)“…Recently, we have shown that ketamine given prior to stress exposure protects against the development of depressive-like behavior in mice. These data suggest…”
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Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2020)“…Enhancing stress resilience in at-risk populations could significantly reduce the incidence of stress-related psychiatric disorders. We have previously…”
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Antidepressant but Not Prophylactic Ketamine Administration Alters Calretinin and Calbindin Expression in the Ventral Hippocampus
Published in Frontiers in molecular neuroscience (06-11-2018)“…Ketamine has been found to have rapid, long-lasting antidepressant effects in treatment-resistant (TR) patients with major depressive disorder (MDD). Recently,…”
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Prophylactic Ketamine Attenuates Learned Fear
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2017)“…Ketamine has been reported to be an efficacious antidepressant for major depressive disorder and posttraumatic stress disorder. Most recently, ketamine has…”
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GluN2B on Adult-Born Granule Cells Modulates (R,S)-Ketamine’s Rapid-Acting Effects in Mice
Published in The international journal of neuropsychopharmacology (01-10-2024)“…Abstract Background Standard antidepressant treatments often take weeks to reach efficacy and are ineffective for many patients. (R,S)-ketamine, an…”
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IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes
Published in Cell reports (Cambridge) (31-05-2022)“…Despite SARS-CoV-2 being a “novel” virus, early detection of anti-spike IgG in severe COVID-19 patients may be caused by the amplification of humoral memory…”
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NF-κB activity affects learning in aversive tasks: Possible actions via modulation of the stress axis
Published in Brain, behavior, and immunity (01-08-2010)“…Abstract The role of altered activity of nuclear factor κB (NF-κB) in specific aspects of motivated behavior and learning and memory was examined in mice…”
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188. Common Neurotransmission Recruited in Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant Effects
Published in Biological psychiatry (1969) (01-05-2018)Get full text
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15
NF-kappaB activity affects learning in aversive tasks: possible actions via modulation of the stress axis
Published in Brain, behavior, and immunity (01-08-2010)“…The role of altered activity of nuclear factor kappaB (NF-kappaB) in specific aspects of motivated behavior and learning and memory was examined in mice…”
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