Search Results - "Bracarda, Sergio"

Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial by Sharma, Padmanee, Prof, Retz, Margitta, Prof, Siefker-Radtke, Arlene, MD, Baron, Ari, MD, Necchi, Andrea, MD, Bedke, Jens, Prof, Plimack, Elizabeth R, MD, Vaena, Daniel, MD, Grimm, Marc-Oliver, Prof, Bracarda, Sergio, MD, Arranz, José Ángel, MD, Pal, Sumanta, MD, Ohyama, Chikara, Prof, Saci, Abdel, PhD, Qu, Xiaotao, PhD, Lambert, Alexandre, PhD, Krishnan, Suba, MD, Azrilevich, Alex, PharmD, Galsky, Matthew D, Prof

“…Summary Background Patients with metastatic urothelial carcinoma have a dismal prognosis and few treatment options after first-line chemotherapy. Responses to…”
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Phase III Trial of Bevacizumab Plus Interferon Alfa-2a in Patients With Metastatic Renal Cell Carcinoma (AVOREN): Final Analysis of Overall Survival by ESCUDIER, Bernard, BELLMUNT, Joaquim, NEGRIER, Sylvie, BAJETTA, Emilio, MELICHAR, Bohuslav, BRACARDA, Sergio, RAVAUD, Alain, GOLDING, Sophie, JETHWA, Sangeeta, SNELLER, Vesna

“…A phase III trial of bevacizumab combined with interferon alfa-2a (IFN) showed significant improvements in progression-free survival (PFS) in metastatic renal…”
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Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial by Gore, Martin E, Prof, Szczylik, Cezary, Prof, Porta, Camillo, MD, Bracarda, Sergio, Prof, Bjarnason, Georg A, MD, Oudard, Stéphane, Prof, Hariharan, Subramanian, MD, Lee, Se-Hoon, MD, Haanen, John, Prof, Castellano, Daniel, MD, Vrdoljak, Eduard, MD, Schöffski, Patrick, Prof, Mainwaring, Paul, Prof, Nieto, Alejandra, MD, Yuan, Jinyu, PhD, Bukowski, Ronald, Prof

“…Summary Background Results from clinical trials have established sunitinib as a standard of care for first-line treatment of advanced or metastatic renal-cell…”
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Another side of the association between body mass index (BMI) and clinical outcomes of cancer patients receiving programmed cell death protein-1 (PD-1)/ Programmed cell death-ligand 1 (PD-L1) checkpoint inhibitors: A multicentre analysis of immune-related adverse events by Cortellini, Alessio, Bersanelli, Melissa, Santini, Daniele, Buti, Sebastiano, Tiseo, Marcello, Cannita, Katia, Perrone, Fabiana, Giusti, Raffaele, De Tursi, Michele, Zoratto, Federica, Marconcini, Riccardo, Russano, Marco, Zeppola, Tea, Anesi, Cecilia, Filetti, Marco, Marchetti, Paolo, Botticelli, Andrea, Gelibter, Alain, De Galitiis, Federica, Vitale, Maria Giuseppa, Rastelli, Francesca, Tudini, Marianna, Silva, Rosa Rita, Atzori, Francesco, Chiari, Rita, Ricciuti, Biagio, De Giglio, Andrea, Migliorino, Maria Rita, Mallardo, Domenico, Vanella, Vito, Mosillo, Claudia, Bracarda, Sergio, Rinaldi, Silvia, Berardi, Rossana, Natoli, Clara, Ficorella, Corrado, Porzio, Giampiero, Ascierto, Paolo A.

“…Several studies have found an association between higher body mass index (BMI) and improved clinical outcomes in cancer patients receiving programmed cell…”
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IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial by Rini, Brian I, Prof, Stenzl, Arnulf, Prof, Zdrojowy, Romauld, Prof, Kogan, Mikhail, Prof, Shkolnik, Mikhail, MD, Oudard, Stephane, Prof, Weikert, Steffen, Prof, Bracarda, Sergio, Prof, Crabb, Simon J, PhD, Bedke, Jens, Prof, Ludwig, Joerg, PhD, Maurer, Dominik, PhD, Mendrzyk, Regina, PhD, Wagner, Claudia, PhD, Mahr, Andrea, PhD, Fritsche, Jens, PhD, Weinschenk, Toni, PhD, Walter, Steffen, PhD, Kirner, Alexandra, PhD, Singh-Jasuja, Harpreet, PhD, Reinhardt, Carsten, MD, Eisen, Tim, FRCP

“…Summary Background In a phase 2 study in patients with metastatic renal cell carcinoma, overall survival was associated with T-cell responses against IMA901, a…”
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Gastrectomy for stage IV gastric cancer: a comparison of different treatment strategies from the SEER database by Desiderio, Jacopo, Sagnotta, Andrea, Terrenato, Irene, Annibale, Bruno, Trastulli, Stefano, Tozzi, Federico, D’Andrea, Vito, Bracarda, Sergio, Garofoli, Eleonora, Fong, Yuman, Woo, Yanghee, Parisi, Amilcare

“…In the West, more than one third of newly diagnosed subjects show metastatic disease in gastric cancer (mGC) with few care options available. Gastrectomy has…”
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Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial by Motzer, Robert J, Dr, Prof, Escudier, Bernard, MD, Oudard, Stéphane, Prof, Hutson, Thomas E, Prof, Porta, Camillo, MD, Bracarda, Sergio, MD, Grünwald, Viktor, Prof, Thompson, John A, Prof, Figlin, Robert A, Prof, Hollaender, Norbert, PhD, Urbanowitz, Gladys, BS, Berg, William J, MD, Kay, Andrea, MD, Lebwohl, David, MD, Ravaud, Alain, Prof

“…Summary Background Everolimus (RAD001) is an orally administered inhibitor of the mammalian target of rapamycin (mTOR), a therapeutic target for metastatic…”
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Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial by Escudier, Bernard, Dr, Prof, Pluzanska, Anna, Prof, Koralewski, Piotr, MD, Ravaud, Alain, Prof, Bracarda, Sergio, Prof, Szczylik, Cezary, Prof, Chevreau, Christine, MD, Filipek, Marek, MD, Melichar, Bohuslav, MD, Bajetta, Emilio, Prof, Gorbunova, Vera, Prof, Bay, Jacques-Olivier, MD, Bodrogi, Istvan, MD, Jagiello-Gruszfeld, Agnieszka, MD, Moore, Nicola, MSc

“…Summary Background Vascular endothelial growth factor (VEGF) inhibition is a valid therapeutic approach in renal cell carcinoma. Therefore, an investigation of…”
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The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide by Del Re, Marzia, Fogli, Stefano, Derosa, Lisa, Massari, Francesco, De Souza, Paul, Crucitta, Stefania, Bracarda, Sergio, Santini, Daniele, Danesi, Romano

“…Graphical abstract…”
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Contemporary Role of Androgen Deprivation Therapy for Prostate Cancer by Pagliarulo, Vincenzo, Bracarda, Sergio, Eisenberger, Mario A, Mottet, Nicolas, Schröder, Fritz H, Sternberg, Cora N, Studer, Urs E

“…Abstract Context Androgen deprivation therapy (ADT) for prostate cancer (PCa) represents one of the most effective systemic palliative treatments known for…”
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Integrated analysis of concomitant medications and oncological outcomes from PD-1/PD-L1 checkpoint inhibitors in clinical practice by Cortellini, Alessio, Tucci, Marco, Adamo, Vincenzo, Stucci, Luigia Stefania, Russo, Alessandro, Tanda, Enrica Teresa, Spagnolo, Francesco, Rastelli, Francesca, Bisonni, Renato, Santini, Daniele, Russano, Marco, Anesi, Cecilia, Giusti, Raffaele, Filetti, Marco, Marchetti, Paolo, Botticelli, Andrea, Gelibter, Alain, Occhipinti, Mario Alberto, Marconcini, Riccardo, Vitale, Maria Giuseppa, Nicolardi, Linda, Chiari, Rita, Bareggi, Claudia, Nigro, Olga, Tuzi, Alessandro, De Tursi, Michele, Petragnani, Nicola, Pala, Laura, Bracarda, Sergio, Macrini, Serena, Inno, Alessandro, Zoratto, Federica, Veltri, Enzo, Di Cocco, Barbara, Mallardo, Domenico, Vitale, Maria Grazia, Pinato, David James, Porzio, Giampiero, Ficorella, Corrado, Ascierto, Paolo Antonio

“…BackgroundConcomitant medications, such as steroids, proton pump inhibitors (PPI) and antibiotics, might affect clinical outcomes with immune checkpoint…”
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Optimal management of metastatic castration-resistant prostate cancer: Highlights from a European Expert Consensus Panel by Fitzpatrick, John M, Bellmunt, Joaquim, Fizazi, Karim, Heidenreich, Axel, Sternberg, Cora N, Tombal, Bertrand, Alcaraz, Antonio, Bahl, Amit, Bracarda, Sergio, Di Lorenzo, Giuseppe, Efstathiou, Eleni, Finn, Stephen P, Fosså, Sophie, Gillessen, Silke, Kellokumpu-Lehtinen, Pirkko-Liisa, Lecouvet, Frédéric E, Oudard, Stephane, de Reijke, Theo M, Robson, Craig N, De Santis, Maria, Seruga, Bostjan, de Wit, Ronald

“…Abstract The exponential growth of novel therapies for the treatment of metastatic castration-resistant prostate cancer (mCRPC) over the last decade has…”
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Cabozantinib After a Previous Immune Checkpoint Inhibitor in Metastatic Renal Cell Carcinoma: A Retrospective Multi-Institutional Analysis by Iacovelli, Roberto, Ciccarese, Chiara, Facchini, Gaetano, Milella, Michele, Urbano, Federica, Basso, Umberto, De Giorgi, Ugo, Sabbatini, Roberto, Santini, Daniele, Berardi, Rossana, Santoni, Matteo, Bracarda, Sergio, Massari, Francesco, Masini, Cristina, De Tursi, Michele, Ricotta, Riccardo, Buti, Sebastiano, Zustovich, Fable, Sepe, Pierangela, Rossetti, Sabrina, Maruzzo, Marco, Cortesi, Enrico, Tortora, Giampaolo, Procopio, Giuseppe

“…Background Angiogenesis has been recognized as the most important factor for tumor invasion, proliferation, and progression in metastatic renal cell carcinoma…”
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Nectin-4 and DNA mismatch repair proteins expression in upper urinary tract urothelial carcinoma (UTUC) as a model for tumor targeting approaches: an ImGO pilot study by Calandrella, Maria Letizia, Francesconi, Simona, Caprera, Cecilia, Mosillo, Claudia, Caserta, Claudia, Giannarelli, Diana, Corsi, Matteo, Macrini, Serena, Guida, Annalisa, Ascani, Stefano, Bracarda, Sergio

“…Upper urinary tract urothelial carcinoma (UTUC) accounts for only about 5-10% of all urothelial cancers and is characterized by an aggressive and frequently…”
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The amount of DNA combined with TP53 mutations in liquid biopsy is associated with clinical outcome of renal cancer patients treated with immunotherapy and VEGFR-TKIs by Del Re, Marzia, Crucitta, Stefania, Paolieri, Federico, Cucchiara, Federico, Verzoni, Elena, Bloise, Francesco, Ciampi, Raffaele, Mercinelli, Chiara, Capuano, Annalisa, Sportiello, Liberata, Martinetti, Antonia, Procopio, Giuseppe, Galli, Luca, Porta, Camillo, Bracarda, Sergio, Danesi, Romano

“…Abstract Background Despite the increasing number of treatment options, reliable prognostic/predictive biomarkers are still missing for patients affected by…”
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Perspectives in Immunotherapy: meeting report from Immunotherapy Bridge (Naples, November 30th-December 1st, 2022) by Ascierto, Paolo A, Avallone, Antonio, Bifulco, Carlo, Bracarda, Sergio, Brody, Joshua D, Emens, Leisha A, Ferris, Robert L, Formenti, Silvia C, Hamid, Omid, Johnson, Douglas B, Kirchhoff, Tomas, Klebanoff, Christopher A, Lesinski, Gregory B, Monette, Anne, Neyns, Bart, Odunsi, Kunle, Paulos, Chrystal M, Powell, Jr, Daniel J, Rezvani, Katayoun, Segal, Brahm H, Singh, Nathan, Sullivan, Ryan J, Fox, Bernard A, Puzanov, Igor

“…The discovery and development of novel treatments that harness the patient's immune system and prevent immune escape has dramatically improved outcomes for…”
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Redefining the role of interferon in the treatment of malignant diseases by Bracarda, Sergio, Eggermont, Alexander M.M, Samuelsson, Jan

“…Abstract Interferon (IFN) is a cytokine with a long history of use as immunotherapy in the treatment of various solid tumours and haematological malignancies…”
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Androgen deprivation therapy and its modulation of PSMA expression in prostate cancer: mini review and case series of patients studied with sequential [68Ga]-Ga-PSMA-11 PET/CT by Mei, Riccardo, Bracarda, Sergio, Emmett, Louise, Farolfi, Andrea, Lambertini, Alessandro, Fanti, Stefano, Castellucci, Paolo

“…Purpose and background [ 68 Ga]-Ga-PSMA-PET/CT (PSMA-PET) is routinely performed in many patients who have received or are receiving Androgen Deprivation…”
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Natural history of malignant bone disease in renal cancer: final results of an Italian bone metastasis survey by Santini, Daniele, Procopio, Giuseppe, Porta, Camillo, Ibrahim, Toni, Barni, Sandro, Mazzara, Calogero, Fontana, Andrea, Berruti, Alfredo, Berardi, Rossana, Vincenzi, Bruno, Ortega, Cinzia, Ottaviani, Davide, Carteni, Giacomo, Lanzetta, Gaetano, Virzì, Vladimir, Santoni, Matteo, Silvestris, Nicola, Satolli, Maria Antonietta, Collovà, Elena, Russo, Antonio, Badalamenti, Giuseppe, Fedeli, Stefano Luzi, Tanca, Francesca Maria, Adamo, Vincenzo, Maiello, Evaristo, Sabbatini, Roberto, Felici, Alessandra, Cinieri, Saverio, Tonini, Giuseppe, Bracarda, Sergio

“…Bone metastasis represents an increasing clinical problem in advanced renal cell carcinoma (RCC) as disease-related survival improves. There are few data on…”
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Circulating Tumor Cells in Renal Cell Carcinoma: Recent Findings and Future Challenges by Santoni, Matteo, Cimadamore, Alessia, Cheng, Liang, Lopez-Beltran, Antonio, Battelli, Nicola, Massari, Francesco, Scarpelli, Marina, Galosi, Andrea Benedetto, Bracarda, Sergio, Montironi, Rodolfo

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