Search Results - "Braas, Karen M"

Parabrachial Pituitary Adenylate Cyclase-Activating Polypeptide Activation of Amygdala Endosomal Extracellular Signal–Regulated Kinase Signaling Regulates the Emotional Component of Pain by Missig, Galen, Mei, Linda, Vizzard, Margaret A, Braas, Karen M, Waschek, James A, Ressler, Kerry J, Hammack, Sayamwong E, May, Victor

“…Abstract Background Chronic pain and stress-related psychopathologies, such as depression and anxiety-associated abnormalities, are mutually reinforcing;…”
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Targeting the PAC1 Receptor for Neurological and Metabolic Disorders by Liao, Chenyi, de Molliens, Mathilde P, Schneebeli, Severin T, Brewer, Matthias, Song, Gaojie, Chatenet, David, Braas, Karen M, May, Victor, Li, Jianing

“…The pituitary adenylate cyclase-activating polypeptide (PACAP)-selective PAC1 receptor (PAC1R, ADCYAP1R1) is a member of the vasoactive intestinal peptide…”
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Parabrachial nucleus (PBn) pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the amygdala: Implication for the sensory and behavioral effects of pain by Missig, Galen, Roman, Carolyn W., Vizzard, Margaret A., Braas, Karen M., Hammack, Sayamwong E., May, Victor

“…The intricate relationships that associate pain, stress responses and emotional behavior have been well established. Acute stressful situations can decrease…”
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PAC1 receptor antagonism in the bed nucleus of the stria terminalis (BNST) attenuates the endocrine and behavioral consequences of chronic stress by Roman, Carolyn W, Lezak, Kim R, Hartsock, Matthew J, Falls, William A, Braas, Karen M, Howard, Alan B, Hammack, Sayamwong E, May, Victor

“…Summary Chronic or repeated stressor exposure can induce a number of maladaptive behavioral and physiological consequences and among limbic structures, the bed…”
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Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): Roles for PACAP in anxiety-like behavior by Hammack, Sayamwong E, Cheung, Joseph, Rhodes, Kimberly M, Schutz, Kristin C, Falls, William A, Braas, Karen M, May, Victor

“…Summary Exposure to chronic stress has been argued to produce maladaptive anxiety-like behavioral states, and many of the brain regions associated with…”
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PACAP in the BNST Produces Anorexia and Weight Loss in Male and Female Rats by KOCHO-SCHELLENBERG, Margaret, LEZAK, Kimberly R, MAY, Victor, HAMMACK, Sayamwong E, HARRIS, Olivia M, ROELKE, Erin, GICK, Niklas, INYOP CHOI, EDWARDS, Shaquille, WASSERMAN, Emily, TOUFEXIS, Donna J, BRAAS, Karen M

“…Recent gene association studies have implicated pituitary adenylate cyclase-activating peptide (PACAP) systems in several psychiatric disorders associated with…”
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Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Potently Dilates Middle Meningeal Arteries: Implications for Migraine by Syed, Arsalan U., Koide, Masayo, Braas, Karen M., May, Victor, Wellman, George C.

“…Migraine is a debilitating neurological disorder characterized by mild to severe headache that is often accompanied by aura and other neurological symptoms…”
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Regulation of Bed Nucleus of the Stria Terminalis PACAP Expression by Stress and Corticosterone by Lezak, Kimberly R., Roman, Carolyn W., Braas, Karen M., Schutz, Kristin C., Falls, William A., Schulkin, Jay, May, Victor, Hammack, Sayamwong E.

“…Single-nucleotide polymorphisms (SNPs) in the genes for pituitary adenylyl cyclase-activating peptide (PACAP) and the PAC1 receptor have been associated with…”
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Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP‐ and PACAP‐deficient mice by Girard, Beatrice A., Lelievre, Vincent, Braas, Karen M., Razinia, Tannaz, Vizzard, Margaret A., Ioffe, Yevgeniya, Meskini, Rajaa El, Ronnett, Gabriele V., Waschek, James A.

“…Pituitary adenylate cyclase‐activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are closely related neurotrophic peptides of the…”
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PACAP-Mediated ATP Release from Rat Urothelium and Regulation of PACAP/VIP and Receptor mRNA in Micturition Pathways after Cyclophosphamide (CYP)-Induced Cystitis by Girard, Beatrice M., Wolf-Johnston, Amanda, Braas, Karen M., Birder, Lori A., May, Victor, Vizzard, Margaret A.

“…Pituitary adenylate cyclase-activating peptide (PACAP) peptides are expressed in micturition pathways, and PACAP expression is regulated by urinary bladder…”
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PACAP orchestration of stress-related responses in neural circuits by Boucher, Melissa N., May, Victor, Braas, Karen M., Hammack, Sayamwong E.

“…•PACAP and its cognate PAC1 receptor are widely distributed in central neural stress circuits.•Central PACAP/PAC1 receptor signaling coordinates stress-related…”
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Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor by Ressler, Kerry J., Mercer, Kristina B., Bradley, Bekh, Jovanovic, Tanja, Mahan, Amy, Kerley, Kimberly, Norrholm, Seth D., Kilaru, Varun, Smith, Alicia K., Myers, Amanda J., Ramirez, Manuel, Engel, Anzhelika, Hammack, Sayamwong E., Toufexis, Donna, Braas, Karen M., Binder, Elisabeth B., May, Victor

“…Pituitary adenylate cyclase-activating polypeptide (PACAP) is known to broadly regulate the cellular stress response. In contrast, it is unclear if the…”
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PAC1 Receptor Internalization and Endosomal MEK/ERK Activation Is Essential for PACAP-Mediated Neuronal Excitability by May, Victor, Johnson, Gregory C., Hammack, Sayamwong E., Braas, Karen M., Parsons, Rodney L.

“…Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1 ) activation of PAC1 receptors ( Adcyap1r1 ) can significantly increase the excitability of…”
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Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) and Vasoactive Intestinal Peptide (VIP) Regulate Murine Neural Progenitor Cell Survival, Proliferation, and Differentiation by Scharf, Eugene, May, Victor, Braas, Karen M., Shutz, Kristin C., Mao-Draayer, Yang

“…Neural stem/progenitor cells (NPC) have gained wide interest over the last decade from their therapeutic potential, either through transplantation or…”
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Activation of Lateral Parabrachial Nucleus (LPBn) PACAP-Expressing Projection Neurons to the Bed Nucleus of the Stria Terminalis (BNST) Enhances Anxiety-like Behavior by Boucher, Melissa N., Aktar, Mahafuza, Braas, Karen M., May, Victor, Hammack, Sayamwong E.

“…Anxiety disorders are among the most common psychiatric disorders, and understanding the underlying neurocircuitry of anxiety- and stress-related behaviors may…”
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Bone morphogenetic protein down‐regulation of neuronal pituitary adenylate cyclase‐activating polypeptide and reciprocal effects on vasoactive intestinal peptide expression by Pavelock, Kristen A., Girard, Beatrice M., Schutz, Kristin C., Braas, Karen M., May, Victor

“…Among bone morphogenetic proteins (BMPs), the decapentaplegic (Dpp; BMP2, BMP4) and glass bottom boat (Gbb/60A; BMP5, BMP6, BMP7) subgroups have well‐described…”
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GPCR Intracellular Loop Regulation of Beta-Arrestin-Mediated Endosomal Signaling Dynamics by Li, Jianing, Remington, Jacob M., Liao, Chenyi, Parsons, Rodney L., Schneebeli, Severin, Braas, Karen M., May, Victor, Brewer, Matthias

“…G protein-coupled receptors (GPCRs) are currently appreciated to be routed to diverse cellular platforms to generate both G protein-dependent and -independent…”
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Pituitary Adenylate Cyclase-activating Polypeptide (PACAP)/PAC1HOP1 Receptor Activation Coordinates Multiple Neurotrophic Signaling Pathways by May, Victor, Lutz, Eve, MacKenzie, Christopher, Schutz, Kristin C., Dozark, Kate, Braas, Karen M.

“…MAPK and Akt pathways are predominant mediators of trophic signaling for many neuronal systems. Among the vasoactive intestinal peptide/secretin/glucagon…”
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Pituitary adenylate cyclase activating polypeptide and PAC1 receptor signaling increase Homer 1a expression in central and peripheral neurons by Girard, Beatrice M., Keller, Emily T., Schutz, Kristin C., May, Victor, Braas, Karen M.

“…Pituitary adenylate cyclase activating polypeptides (PACAP) and PAC1 receptor signaling have diverse roles in central and peripheral nervous system development…”
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Pituitary Adenylate Cyclase-Activating Polypeptide Expression and Modulation of Neuronal Excitability in Guinea Pig Cardiac Ganglia by Braas, Karen M, May, Victor, Harakall, Susan A, Hardwick, Jean C, Parsons, Rodney L

“…Cardiac output is regulated by the coordinate interactions of stimulatory sympathetic and inhibitory parasympathetic signals. Intracardiac parasympathetic…”
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