Search Results - "Bräutigam, Maria"

Synthetic Oligosaccharide-Based Vaccines Protect Mice from Clostridioides difficile Infections by Broecker, Felix, Wegner, Erik, Seco, Bruna M. S, Kaplonek, Paulina, Bräutigam, Maria, Ensser, Armin, Pfister, Frederick, Daniel, Christoph, Martin, Christopher E, Mattner, Jochen, Seeberger, Peter H

“…Infections with Clostridioides difficile (formerly Clostridium difficile) have increased in incidence, morbidity, and mortality over the past decade…”
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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells by Lustig, Marta, Chan, Chilam, Jansen, J H Marco, Bräutigam, Maria, Kölling, Max A, Gehlert, Carina Lynn, Baumann, Niklas, Mester, Simone, Foss, Stian, Andersen, Jan Terje, Bastian, Lorenz, Sondermann, Peter, Peipp, Matthias, Burger, Renate, Leusen, Jeanette H W, Valerius, Thomas

“…Upregulation of surface expressed sialoglycans on tumor cells is one of the mechanisms which promote tumor growth and progression. Specifically, the…”
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Synthetic Approaches to Mono- and Bicyclic Perortho-Esters with a Central 1,2,4-Trioxane Ring as the Privileged Lead Structure in Antimalarial and Antitumor-Active Peroxides and Clarification of the Peroxide Relevance by Griesbeck, Axel G, Bräutigam, Maria, Kleczka, Margarethe, Raabe, Angela

“…The synthesis of 4-styryl-substituted 2,3,8-trioxabicyclo[3.3.1]nonanes, peroxides with the core structure of the bioactive 1,2,4-trioxane ring, was conducted…”
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Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5-Methylated 1,2,4-Trioxanes with C6-Acrylate Side Chains by Griesbeck, Axel G., Maaßen, Andreas, Bräutigam, Maria, Pietsch, Markus

“…The 1,2‐hydroxy hydroperoxide 7 was obtained with high threo diastereoselectivity from the ester‐conjugated allylic alcohol 6 through a porphyrin‐sensitized…”
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Automated glycan assembly of Lewis type I and II oligosaccharide antigens† †Electronic supplementary information (ESI) available: Full experimental information, HPLC chromatograms for AGA syntheses, 1H, 13C, COSY and HSQC NMR spectra of all new compounds. See DOI: 10.1039/c9sc00768g by Guberman, Mónica, Bräutigam, Maria, Seeberger, Peter H.

“…Lewis antigens are fucosylated oligosaccharides that play crucial roles in various biological processes. Here, we illustrate how automated glycan assembly…”
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Automated glycan assembly of Lewis type I and II oligosaccharide antigens by Guberman, Mónica, Bräutigam, Maria, Seeberger, Peter H

“…Human blood group related glycan antigens are fucosylated (neo-)lactoseries oligosaccharides that play crucial roles in pathogenic processes. Lewis…”
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Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5-Methylated 1,2,4-Trioxanes with C6-Acrylate Side Chains (Eur. J. Org. Chem. 20/2015) by Griesbeck, Axel G., Maaßen, Andreas, Bräutigam, Maria, Pietsch, Markus

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Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents by Bräutigam, Maria, Teusch, Nicole, Schenk, Tobias, Sheikh, Miriam, Aricioglu, Rocky Z., Borowski, Swantje H., Neudörfl, Jörg-Martin, Baumann, Ulrich, Griesbeck, Axel G., Pietsch, Markus

“…The response to chemotherapy in cancer patients is frequently compromised by drug resistance. Although chemoresistance is a multifactorial phenomenon, many…”
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A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN by Wawrzinek, Robert, Wamhoff, Eike-Christian, Lefebre, Jonathan, Rentzsch, Mareike, Bachem, Gunnar, Domeniconi, Gary, Schulze, Jessica, Fuchsberger, Felix F, Zhang, Hengxi, Modenutti, Carlos, Schnirch, Lennart, Marti, Marcelo A, Schwardt, Oliver, Bräutigam, Maria, Guberman, Mónica, Hauck, Dirk, Seeberger, Peter H, Seitz, Oliver, Titz, Alexander, Ernst, Beat, Rademacher, Christoph

“…Dendritic cells (DC) are antigen-presenting cells coordinating the interplay of the innate and the adaptive immune response. The endocytic C-type lectin…”
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A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae by Kaplonek, Paulina, Yao, Ling, Reppe, Katrin, Voß, Franziska, Kohler, Thomas, Ebner, Friederike, Schäfer, Alexander, Blohm, Ulrike, Priegue, Patricia, Bräutigam, Maria, Pereira, Claney L., Parameswarappa, Sharavathi G., Emmadi, Madhu, Ménová, Petra, Witzenrath, Martin, Hammerschmidt, Sven, Hartmann, Susanne, Sander, Leif E., Seeberger, Peter H.

“…Streptococcus pneumoniae (S. pneumoniae)infections are the leading cause of child mortality globally. Currentvaccines fail to induceaprotective immune response…”
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Abstract 3125: TCX-101, a novel antibody-drug conjugate targeting a tumor-associated carbohydrate antigen for the treatment of solid tumors by Gomes, Fausto G., Muraca, Francesco, Moreira, Gustavo M. Schmidt Garcia, Rösch, Kathrin, Bräutigam, Maria, Sondermann, Peter, Ocker, Matthias

“…Tumor-associated carbohydrate antigens (TACAs) are short oligosaccharides expressed on the surface of cancer cells and play key roles in cellular…”
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Back Cover: Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents (ChemMedChem 4/2015) by Bräutigam, Maria, Teusch, Nicole, Schenk, Tobias, Sheikh, Miriam, Aricioglu, Rocky Z., Borowski, Swantje H., Neudörfl, Jörg-Martin, Baumann, Ulrich, Griesbeck, Axel G., Pietsch, Markus

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