Search Results - "Brůha, Radan"

Osteopontin – A potential biomarker of advanced liver disease by Bruha, Radan, Vitek, Libor, Smid, Vaclav

“…Cirrhosis is a primary cause of liver-related mortality and morbidity. The basic process driving chronic liver disease to cirrhosis is accelerated…”
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Clinically silent LINE 1 insertion in the PNPLA3 gene may impede genotyping of the p.I148M variant by Leníček, Martin, Šmíd, Václav, Pajer, Petr, Nazarova, Anna, Dvořák, Karel, Subhanová, Iva, Brůha, Radan, Vítek, Libor

“…The patatin-like phospholipase domain containing 3 ( PNPLA3 ) gene (viz. its I148M variant) is one of the key players in the pathogenesis of nonalcoholic fatty…”
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The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline-Deficient Diet in Mice by Šmíd, Václav, Dvořák, Karel, Stehnová, Kamila, Strnad, Hynek, Rubert, Josep, Stříteský, Jan, Staňková, Barbora, Stránská, Milena, Hajšlová, Jana, Brůha, Radan, Vítek, Libor

“…The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is associated with abnormalities of liver lipid metabolism. On the contrary, a diet enriched with…”
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Non-Alcoholic Fatty Liver Disease by Brůha, Radan

“…Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of a metabolic syndrome, is a leading cause of chronic liver disease worldwide with…”
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Serum concentration of taurochenodeoxycholic acid predicts clinically significant portal hypertension by Žížalová, Kateřina, Nováková, Barbora, Vecka, Marek, Petrtýl, Jaromír, Lánská, Věra, Pelinková, Květa, Šmíd, Václav, Brůha, Radan, Vítek, Libor, Leníček, Martin

“…Background & Aims Severity of portal hypertension is usually quantified by measuring the hepatic venous pressure gradient (HVPG). However, due to its…”
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Alcoholic liver disease by Bruha, Radan, Dvorak, Karel, Petrtyl, Jaromir

“…Alcohol use disorders affect millions of individuals worldwide.Alcohol consumption is directly associated with liver disease mortality and accounts for…”
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Biomarkers of hepatocellular synthesis in patients with decompensated cirrhosis by Gurbuz, Berivan, Guldiken, Nurdan, Reuken, Philipp, Fu, Lei, Remih, Katharina, Preisinger, Christian, Brůha, Radan, Leníček, Martin, Petrtýl, Jaromír, Reissing, Johanna, Aly, Mahmoud, Fromme, Malin, Zhou, Biaohuan, Karkossa, Isabel, Schubert, Kristin, von Bergen, Martin, Stallmach, Andreas, Bruns, Tony, Strnad, Pavel

“…Background and aim Since hepatocytes produce majority of serum proteins, patients with cirrhosis display substantial alterations in the serum proteome. The aim…”
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Effect of Omega‐3 Polyunsaturated Fatty Acids on Lipid Metabolism in Patients With Metabolic Syndrome and NAFLD by Šmíd, Václav, Dvořák, Karel, Šedivý, Petr, Kosek, Vít, Leníček, Martin, Dezortová, Monika, Hajšlová, Jana, Hájek, Milan, Vítek, Libor, Bechyňská, Kamila, Brůha, Radan

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. n‐3 polyunsaturated fatty acids (n‐3‐PUFAs) have been reported to ameliorate…”
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Associations of plasma phospholipid cis-vaccenic acid with insulin resistance markers in non-diabetic men with hyperlipidemia by Macášek, Jaroslav, Staňková, Barbora, Žák, Aleš, Růžičková, Markéta, Brůha, Radan, Kutová, Simona, Vecka, Marek, Zeman, Miroslav

“…Background The role of fatty acids (FA) in the pathogenesis of insulin resistance and hyperlipidemia is a subject of intensive research. Several recent works…”
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Use of non-invasive parameters of non-alcoholic steatohepatitis and liver fibrosis in daily practice--an exploratory case-control study by Dvorak, Karel, Stritesky, Jan, Petrtyl, Jaromir, Vitek, Libor, Sroubkova, Renata, Lenicek, Martin, Smid, Vaclav, Haluzik, Martin, Bruha, Radan

“…Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of a metabolic syndrome. To date, liver biopsy has been the gold standard used to…”
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Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts by Mayo, Rebeca, Crespo, Javier, Martínez‐Arranz, Ibon, Banales, Jesus M, Arias, Mayte, Mincholé, Itziar, Aller de la Fuente, Rocío, Jimenez‐Agüero, Raúl, Alonso, Cristina, de Luis, Daniel A., Vitek, Libor, Stritesky, Jan, Caballería, Joan, Romero‐Gómez, Manuel, Martín‐Duce, Antonio, Mugüerza Huguet, Jose Maria, Busteros‐Moraza, José Ignacio, Idowu, Michael O., Castro, Azucena, Martínez‐Chantar, M. Luz, Ortiz, Pablo, Bruha, Radan, Lu, Shelly C., Bedossa, Pierre, Noureddin, Mazen, Sanyal, Arun J., Mato, José M.

“…Nonalcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease worldwide and includes a broad spectrum of histologic phenotypes,…”
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Pathogenesis of Wilson disease by Scheiber, Ivo Florin, Brůha, Radan, Dušek, Petr

“…Wilson disease is an autosomal-recessive disorder originating from a genetic defect in the copper-transporting ATPase ATP7B that is required for biliary copper…”
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Osteopontin: A non-invasive parameter of portal hypertension and prognostic marker of cirrhosis by Bruha, Radan, Jachymova, Marie, Petrtyl, Jaromir, Dvorak, Karel, Lenicek, Martin, Urbanek, Petr, Svestka, Tomislav, Vitek, Libor

“…AIM: To investigate the relationship between osteopontin plasma concentrations and the severity of portal hypertension and to assess osteopontin prognostic…”
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Association of Serum Bilirubin and Functional Variants of Heme Oxygenase 1 and Bilirubin UDP-Glucuronosyl Transferase Genes in Czech Adult Patients with Non-Alcoholic Fatty Liver Disease by Petrtýl, Jaromír, Dvořák, Karel, Stříteský, Jan, Leníček, Martin, Jirásková, Alena, Šmíd, Václav, Haluzík, Martin, Brůha, Radan, Vítek, Libor

“…Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disorder worldwide. The aim of our study was to assess the role of bilirubin, and…”
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Long-term follow-up of Wilson Disease: natural history, treatment, mutations analysis and phenotypic correlation by Bruha, Radan, Marecek, Zdenek, Pospisilova, Lenka, Nevsimalova, Sona, Vitek, Libor, Martasek, Pavel, Nevoral, Jiri, Petrtyl, Jaromir, Urbanek, Petr, Jiraskova, Alena, Ferenci, Peter

“…Background and aims: Wilson disease (WD) is an inherited disorder of copper metabolism. When treated, the outcome can be excellent, although the long‐term…”
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Serum markers in diagnostics of steatohepatitis by Nováková, Barbora, Brůha, Radan

“…Along with the increasing incidence and prevalence of obesity and the metabolic syndrome, the number of patients with its hepatic manifestation - NAFL,…”
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Pancreatic Injury in Patients with SARS-Cov-2 (COVID-19) Infection: A Retrospective Analysis of CT Findings by Grusova, Gabriela, Bruha, Radan, Bircakova, Bianka, Novak, Matej, Lambert, Lukas, Michalek, Pavel, Tomas, Grus, Burgetova, Andrea

“…Objective. To determine the association between COVID-19 infection and peripancreatic changes on CT as a sign of acute pancreatic injury. Methods…”
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Approach to patients with liver diseases by Brůha, Radan

“…In recent years the most frequent cause of chronic liver diseases in western countries has become Non-alcoholic hepatic steatosis/steatohepatitis (NAFLD/NASH)…”
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The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge? by Lazarus, Jeffrey V., Mark, Henry E., Villota-Rivas, Marcela, Palayew, Adam, Colombo, Massimo, Ekstedt, Mattias, Esmat, Gamal, Marchesini, Giulio, Novak, Katja, Ocama, Ponsiano, Ratziu, Vlad, Razavi, Homie, Romero-Gómez, Manuel, Spearman, C. Wendy, Tacke, Frank, Tsochatzis, Emmanuel A., Yilmaz, Yusuf, Younossi, Zobair M., Wong, Vincent W.-S., Zelber-Sagi, Shira, Cortez-Pinto, Helena, Anstee, Quentin M., Rouabhia, Samir, Ghazinyan, Hasmik, Iskandar, Natacha Jreige, Aghayeva, Gulnara, Carter, Flloyd, Sridharan, Kannan, Al Mahtab, Mamun, Francque, Sven, Kodjoh, Nicolas, Camacho, Ruben Muñoz, Marques Souza de Oliveira, Claudia Pinto, Serme, Abdel Karim, Soares Martins, Antonieta A., Swain, Mark G., Komas, Narcisse Patrice, Jaramillo, Patricio Lopez, Murillo, Omar Alfaro, Mikolasevic, Ivana, Vounou, Emmelia, Brůha, Radan, Perez, Marlene, Suárez M, Juan José, Waked, Imam, Salupere, Riina, Desalegn, Hailemichael, Tsertsvadze, Tengiz, Sharvadze, Lali, Butsashvili, Maia, Awuku, Yaw Asante, Papatheodoridis, Georgios, Bjornsson, Einar Stefan, Duseja, Ajay, Lesmana, Cosmas Rinaldi A., Malekzadeh, Reza, Norris, Suzanne, Koike, Kazuhiko, Nersesov, Alexander V., Ochwoto, Missiani, Jamal, Mohammad, Saparbu, Tobokalova, Tolmane, Ieva, Sayegh, Raymond, Sheriff, Dhastagir Sultan, Weber, Joseph, Shawa, Isaac Thom, Tan, Soek-Siam, Martínez Vázquez, Sophia E., Baatarkhuu, Oidov, Lkhagvaa, Undram, Mohammed, Tahiri, Sudhamshu, K.C, Onyekwere, Charles, Nikolova, Dafina, Vesterhus, Mette, Al-Naamani, Khalid, Hamid, Saeed, Méndez, Juan Paredes, Cabrera Cabrejos, María Cecilia, Flisiak, Robert, Torres, Esther A., Taheri, Shahrad, Sung, Ki-Chul, Adela, Turcanu, Gheorghe, Liana, Sanai, Faisal M., Milovanovic, Tamara, Bee Goh, George Boon, Rac, Marek, Dassanayake, Anuradha, Osama, Shahinaz Bedri, Elsanousi, M., Dufour, Jean-François, Kao, Jia-Horng, Saidi, Dilshod, Treeprasertsuk, Sombat, Koek, Ger, Skrypnyk, Igor, Sinkala, Edford

“…Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and…”
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Comparison of transcranial sonography-magnetic resonance fusion imaging in Wilson's and early-onset Parkinson's diseases by Mašková, Jana, Školoudík, David, Burgetová, Andrea, Fiala, Ondřej, Brůha, Radan, Záhoráková, Daniela, Serranová, Tereza, Slovák, Matěj, Ulmanová, Olga, Růžička, Evžen, Dušek, Petr

“…Abstract Introduction Wilson's disease (WD) is a hereditary disorder caused by ATP7B mutations resulting in systemic copper accumulation. WD may manifest as…”
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