Search Results - "Brüning, B."

Influence of charge density on bilayer bending rigidity in lipid vesicles: A combined dynamic light scattering and neutron spin-echo study by Brüning, B., Stehle, R., Falus, P., Farago, B.

“…We report a combined dynamic light scattering and neutron spin-echo study on vesicles composed of the uncharged stabilizing lipid…”
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Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores by Schmeller, T., Latz-Brüning, B., Wink, M.

“…The alkaloids berberine, palmatine and sanguinarine are toxic to insects and vertebrates and inhibit the multiplication of bacteria, fungi and viruses…”
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The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes by Frkic, Rebecca L., Richter, Katharina, Bruning, John B.

“…A promising approach for treating type 2 diabetes mellitus (T2DM) is to target the Peroxisome Proliferator-Activated Receptor γ (PPARγ) transcription factor,…”
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Perfluorinated surfactants as model charged systems for understanding the effect of confinement on proton transport and water mobility in fuel cell membranes. A study by QENS by Lyonnard, S., Berrod, Q., Brüning, B.-A., Gebel, G., Guillermo, A., Ftouni, H., Ollivier, J., Frick, B.

“… We have investigated the dynamical properties of water confined in mesomorphous phases of perfluorinated sulfonic surfactants. These systems mimic the…”
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Influence of cholesterol on the collective dynamics of the phospholipid acyl chains in model membranes by Brüning, B., Rheinstädter, M. C., Hiess, A., Weinhausen, B., Reusch, T., Aeffner, S., Salditt, T.

“…We have studied the packing and collective dynamics of the phospholipid acyl chains in a model membrane composed of…”
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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism by Kroker, Alice J., Bruning, John B.

“…PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor of the nuclear receptor superfamily that controls the…”
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Perfluorooctanoic acid rigidifies a model lipid membrane by Brüning, B, Farago, B

“…We report a combined dynamic light scattering and neutron spin-echo (NSE) study on vesicles composed of the phospholipid…”
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A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis by Mohamed, Hebatalla, Child, Stella A., Bruning, John B., Bell, Stephen G.

“…Members of the CYP51 family of cytochrome P450 enzymes are classified as sterol demethylases involved in the metabolic formation of cholesterol and related…”
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Structural mechanism for signal transduction in RXR nuclear receptor heterodimers by Kojetin, Douglas J., Matta-Camacho, Edna, Hughes, Travis S., Srinivasan, Sathish, Nwachukwu, Jerome C., Cavett, Valerie, Nowak, Jason, Chalmers, Michael J., Marciano, David P., Kamenecka, Theodore M., Shulman, Andrew I., Rance, Mark, Griffin, Patrick R., Bruning, John B., Nettles, Kendall W.

“…A subset of nuclear receptors (NRs) function as obligate heterodimers with retinoid X receptor (RXR), allowing integration of ligand-dependent signals across…”
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Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor by Stevens, Tristan, Song, Sisi, Bruning, John B., Choo, Amanda, Baxter, Simon W.

“…Bt toxins ingested by insect pests can bind to midgut receptors and cause death, although several steps in this process remain unclear. Multiple Bt toxin…”
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An improved methodology to evaluate crop salt tolerance from field trials by van Straten, G., de Vos, A.C., Rozema, J., Bruning, B., van Bodegom, P.M.

“…•Solid method to estimate salt tolerance parameters from field trials.•Statistical analysis of parameter bias, uncertainty and correlation.•Salinity thresholds…”
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DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex by Zhang, Jun, Chalmers, Michael J, Stayrook, Keith R, Burris, Lorri L, Wang, Yongjun, Busby, Scott A, Pascal, Bruce D, Garcia-Ordonez, Ruben D, Bruning, John B, Istrate, Monica A, Kojetin, Douglas J, Dodge, Jeffrey A, Burris, Thomas P, Griffin, Patrick R

“…A comprehensive HDX analysis of the vitamin D receptor–retinoid X receptor (VDR-RXR) reveals extensive allosteric communication within the same polypeptide…”
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Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-δ p66 Subunit and Flap Endonuclease-1 by Bruning, John B., Shamoo, Yousif

“…Human Proliferating Cellular Nuclear Antigen (hPCNA), a member of the sliding clamp family of proteins, makes specific protein-protein interactions with DNA…”
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Structure of the Mycobacterium tuberculosis d-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine by BRUNING, John B, MURILLO, Ana C, CHACON, Ofelia, BARLETTA, Raúl G, SACCHETTINI, James C

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features by Bonnefond, Amélie, Raimondo, Anne, Stutzmann, Fanny, Ghoussaini, Maya, Ramachandrappa, Shwetha, Bersten, David C, Durand, Emmanuelle, Vatin, Vincent, Balkau, Beverley, Lantieri, Olivier, Raverdy, Violeta, Pattou, François, Van Hul, Wim, Van Gaal, Luc, Peet, Daniel J, Weill, Jacques, Miller, Jennifer L, Horber, Fritz, Goldstone, Anthony P, Driscoll, Daniel J, Bruning, John B, Meyre, David, Whitelaw, Murray L, Froguel, Philippe

“…Sim1 haploinsufficiency in mice induces hyperphagic obesity and developmental abnormalities of the brain. In humans, abnormalities in chromosome 6q16, a region…”
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HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions by Zheng, Jie, Chang, Mi Ra, Stites, Ryan E., Wang, Yong, Bruning, John B., Pascal, Bruce D., Novick, Scott J., Garcia-Ordonez, Ruben D., Stayrook, Keith R., Chalmers, Michael J., Dodge, Jeffrey A., Griffin, Patrick R.

“…The vitamin D receptor/retinoid X receptor-α heterodimer (VDRRXRα) regulates bone mineralization via transcriptional control of osteocalcin ( BGLAP ) gene and…”
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Coupling of receptor conformation and ligand orientation determine graded activity by Nettles, Kendall W, Bruning, John B, Parent, Alexander A, Gil, German, Zhao, Min, Nowak, Jason, Pace, Margaret C, Smith, Carolyn L, Afonine, Pavel V, Adams, Paul D, Katzenellenbogen, John A

“…The ability of constrained mutants of the estrogen receptor ligand-binding domain to dictate different conformations of bound partial agonists indicates that…”
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Targeting Unconventional Pathways in Pursuit of Novel Antifungals by Nguyen, Stephanie, Truong, Jia Q, Bruning, John B

“…The impact of invasive fungal infections on human health is a serious, but largely overlooked, public health issue. Commonly affecting the immunocompromised…”
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Biochemical and in silico characterization of glycosyltransferases from red sweet cherry (Prunus avium L.) reveals their broad specificity toward phenolic substrates by Clayton-Cuch, Daniel, Yu, Long, McDougal, Daniel, Burbidge, Crista A., Bruning, John B., Bradley, David, Böttcher, Christine, Bulone, Vincent

“…•Two glycosyltransferases from sweet cherry, PaUGT1 and PaUGT2, are described.•Both show glucosyltransferase and weaker galactosyltransferase activities.•Both…”
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Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes by Thompson, Andrew P, Salaemae, Wanisa, Pederick, Jordan L, Abell, Andrew D, Booker, Grant W, Bruning, John B, Wegener, Kate L, Polyak, Steven W

“…The penultimate step in the biosynthesis of biotin is the closure of the ureido heterocycle in a reaction requiring a nucleoside triphosphate (NTP). In…”
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