Search Results - "Brümmendorf, Tim Henrik"

Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms by Bermes, Max, Rodriguez, Maria Jimena, de Toledo, Marcelo Augusto Szymanski, Ernst, Sabrina, Müller-Newen, Gerhard, Brümmendorf, Tim Henrik, Chatain, Nicolas, Koschmieder, Steffen, Baumeister, Julian

“…Myeloproliferative neoplasms (MPN) are rare hematologic disorders characterized by clonal hematopoiesis. Familial clustering is observed in a subset of cases,…”
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Low Level Her2 Overexpression Is Associated with Rapid Tumor Cell Proliferation and Poor Prognosis in Prostate Cancer by MINNER, Sarah, JESSEN, Birte, BOKEMEYER, Carsten, SIMON, Ronald, STEUBER, Thomas, GRAEFEN, Markus, HULAND, Hartwig, SAUTER, Guido, SCHLOMM, Thorsten, STIEDENROTH, Lars, BURANDT, Eike, KÖLLERMANN, Jens, MIRLACHER, Martina, ERBERSDOBLER, Andreas, EICHELBERG, Christian, FISCH, Margit, HENRIK BRÜMMENDORF, Tim

“…The HER2 oncogene is involved in the biology of many different tumor types and serves as a prognostic marker and a therapeutic target in breast cancer. In…”
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Detection of Karyotype Evolution From Peripheral Blood by Sequential FISH Analyses of Circulating CD34+ Cells In MDS Patients: Results of the Ongoing German Multicenter Prospective Diagnostic Study by Braulke, Friederike, Schanz, Julie, Metz, Michael, Detken, Sven, Seraphin, Joerg, Götze, Katharina, Mueller-Thomas, Catharina, Platzbecker, Uwe, Brümmendorf, Tim Henrik, Giagounidis, Aristoteles A.N., Germing, Ulrich, Jentsch-Ullrich, Kathleen, Boehme, Angelika, Bug, Gesine, Ottmann, Oliver G., Schafhausen, Philippe, Trümper, Lorenz, Haase, Detlef

“…Abstract 2937 Chromosomal aberrations in myelodysplastic syndromes (MDS) play a major role in diagnostics, pathogenesis, prognosis, and, more recently, in…”
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Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation by Ferreira, Monica Sofia Ventura, Sørensen, Mia Dahl, Pusch, Stefan, Beier, Dagmar, Bouillon, Anne-Sophie, Kristensen, Bjarne Winther, Brümmendorf, Tim Henrik, Beier, Christoph Patrick, Beier, Fabian

“…Purpose Isocitrate dehydrogenase 1 (IDH1) mutations are associated with improved survival in gliomas. Depending on the IDH1 status, TERT promoter mutations…”
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A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generation c-ABL therapy by Borthakur, Gautam, Dombret, Herve, Schafhausen, Philippe, Brummendorf, Tim Henrik, Boissel, Nicolas, Jabbour, Elias, Mariani, Mariangela, Capolongo, Laura, Carpinelli, Patrizia, Davite, Cristina, Kantarjian, Hagop, Cortes, Jorge E

“…Danusertib is a pan-aurora kinase inhibitor with potent activity against Abl kinase including the gatekeeper T315I mutant. A phase 1 dose escalation study of…”
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The Fc‐alpha receptor is a new target antigen for immunotherapy of myeloid leukemia by Mladenov, Radoslav, Hristodorov, Dmitrij, Cremer, Christian, Hein, Lea, Kreutzer, Fabian, Stroisch, Tim, Niesen, Judith, Brehm, Hannes, Blume, Tobias, Brümmendorf, Tim Henrik, Jost, Edgar, Thepen, Theophilus, Fischer, Rainer, Stockmeyer, Bernhard, Barth, Stefan, Stein, Christoph

“…Antibody‐based immunotherapy of leukemia requires the targeting of specific antigens on the surface of blasts. The Fc gamma receptor (CD64) has been…”
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Aging of blood can be tracked by DNA methylation changes at just three CpG sites by Weidner, Carola Ingrid, Lin, Qiong, Koch, Carmen Maike, Eisele, Lewin, Beier, Fabian, Ziegler, Patrick, Bauerschlag, Dirk Olaf, Jöckel, Karl-Heinz, Erbel, Raimund, Mühleisen, Thomas Walter, Zenke, Martin, Brümmendorf, Tim Henrik, Wagner, Wolfgang

“…BACKGROUND: Human aging is associated with DNA methylation changes at specific sites in the genome. These epigenetic modifications may be used to track donor…”
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Additional benefits of telomere length (TL) measurements in chronic lymphocytic leukemia by Kaifie, Andrea, Schikowsky, Christian, Vasko, Theresa, Kraus, Thomas, Brümmendorf, Tim Henrik, Ziegler, Patrick

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