Search Results - "Brügger, Britta"

Lipidomics: Analysis of the Lipid Composition of Cells and Subcellular Organelles by Electrospray Ionization Mass Spectrometry by Brügger, Britta

“…Lipidomics aims to quantitatively define lipid classes, including their molecular species, in biological systems. Lipidomics has experienced rapid progress,…”
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Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes by Trajkovic, Katarina, Hsu, Chieh, Chiantia, Salvatore, Rajendran, Lawrence, Wenzel, Dirk, Wieland, Felix, Schwille, Petra, Brügger, Britta, Simons, Mikael

“…Intraluminal vesicles of multivesicular endosomes are either sorted for cargo degradation into lysosomes or secreted as exosomes into the extracellular milieu…”
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Public LC-Orbitrap Tandem Mass Spectral Library for Metabolite Identification by Phapale, Prasad, Palmer, Andrew, Gathungu, Rose Muthoni, Kale, Dipali, Brügger, Britta, Alexandrov, Theodore

“…Liquid chromatography–mass spectrometry (LC-MS)-based untargeted metabolomics studies require high-quality spectral libraries for reliable metabolite…”
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Chemical Tools for Lipid Cell Biology by Schultz, Carsten, Brügger, Britta

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Quantification of Dolichyl Phosphates Using Phosphate Methylation and Reverse-Phase Liquid Chromatography–High Resolution Mass Spectrometry by Kale, Dipali, Kikul, Frauke, Phapale, Prasad, Beedgen, Lars, Thiel, Christian, Brügger, Britta

“…Dolichyl monophosphates (DolPs) are essential lipids in glycosylation pathways that are highly conserved across almost all domains of life. The availability of…”
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Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites by Malek, Mouhannad, Wawrzyniak, Anna M., Koch, Peter, Lüchtenborg, Christian, Hessenberger, Manuel, Sachsenheimer, Timo, Jang, Wonyul, Brügger, Britta, Haucke, Volker

“…Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of tethers to contact…”
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Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation by Tabata, Keisuke, Prasad, Vibhu, Paul, David, Lee, Ji-Young, Pham, Minh-Tu, Twu, Woan-Ing, Neufeldt, Christopher J., Cortese, Mirko, Cerikan, Berati, Stahl, Yannick, Joecks, Sebastian, Tran, Cong Si, Lüchtenborg, Christian, V’kovski, Philip, Hörmann, Katrin, Müller, André C., Zitzmann, Carolin, Haselmann, Uta, Beneke, Jürgen, Kaderali, Lars, Erfle, Holger, Thiel, Volker, Lohmann, Volker, Superti-Furga, Giulio, Brügger, Britta, Bartenschlager, Ralf

“…Double membrane vesicles (DMVs) serve as replication organelles of plus-strand RNA viruses such as hepatitis C virus (HCV) and SARS-CoV-2. Viral DMVs are…”
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Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions by Haberkant, Per, Stein, Frank, Höglinger, Doris, Gerl, Mathias J., Brügger, Britta, Van Veldhoven, Paul P., Krijgsveld, Jeroen, Gavin, Anne-Claude, Schultz, Carsten

“…Sphingolipids are essential structural components of cellular membranes and are crucial regulators of cellular processes. While current high-throughput…”
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Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins by Nůsková, Hana, Serebryakova, Marina V., Ferrer-Caelles, Anna, Sachsenheimer, Timo, Lüchtenborg, Christian, Miller, Aubry K., Brügger, Britta, Kordyukova, Larisa V., Teleman, Aurelio A.

“…Covalent attachment of C16:0 to proteins (palmitoylation) regulates protein function. Proteins are also S-acylated by other fatty acids including C18:0…”
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Molecular Anatomy of a Trafficking Organelle by Takamori, Shigeo, Holt, Matthew, Stenius, Katinka, Lemke, Edward A., Grønborg, Mads, Riedel, Dietmar, Urlaub, Henning, Schenck, Stephan, Brügger, Britta, Ringler, Philippe, Müller, Shirley A., Rammner, Burkhard, Gräter, Frauke, Hub, Jochen S., De Groot, Bert L., Mieskes, Gottfried, Moriyama, Yoshinori, Klingauf, Jürgen, Grubmüller, Helmut, Heuser, John, Wieland, Felix, Jahn, Reinhard

“…Membrane traffic in eukaryotic cells involves transport of vesicles that bud from a donor compartment and fuse with an acceptor compartment. Common principles…”
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The HIV Lipidome: A Raft with an Unusual Composition by Brügger, Britta, Glass, Bärbel, Haberkant, Per, Leibrecht, Iris, Wieland, Felix T., Kräusslich, Hans-Georg

“…The lipids of enveloped viruses play critical roles in viral morphogenesis and infectivity. They are derived from the host membranes from which virus budding…”
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Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain by Contreras, F.-Xabier, Ernst, Andreas M., Haberkant, Per, Björkholm, Patrik, Lindahl, Erik, Gönen, Başak, Tischer, Christian, Elofsson, Arne, von Heijne, Gunnar, Thiele, Christoph, Pepperkok, Rainer, Wieland, Felix, Brügger, Britta

“…A sphingomyelin-binding motif is identified in the membrane-spanning domain of p24, a COPI machinery protein. Sphingolipid recognition by membrane proteins…”
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Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis by Tan, Tao, Ozbalci, Cagakan, Brügger, Britta, Rapaport, Doron, Dimmer, Kai Stefan

“…The yeast mitochondrial outer membrane (MOM) protein Mdm10 is involved in at least three different processes: (1) association of mitochondria with the…”
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Morphology and Molecular Composition of Purified Bovine Viral Diarrhea Virus Envelope by Callens, Nathalie, Brügger, Britta, Bonnafous, Pierre, Drobecq, Hervé, Gerl, Mathias J, Krey, Thomas, Roman-Sosa, Gleyder, Rümenapf, Till, Lambert, Olivier, Dubuisson, Jean, Rouillé, Yves

“…The family Flaviviridae includes viruses that have different virion structures and morphogenesis mechanisms. Most cellular and molecular studies have been so…”
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Cholesterol promotes clustering of PI(4,5)P2 driving unconventional secretion of FGF2 by Lolicato, Fabio, Saleppico, Roberto, Griffo, Alessandra, Meyer, Annalena, Scollo, Federica, Pokrandt, Bianca, Müller, Hans-Michael, Ewers, Helge, Hähl, Hendrik, Fleury, Jean-Baptiste, Seemann, Ralf, Hof, Martin, Brügger, Britta, Jacobs, Karin, Vattulainen, Ilpo, Nickel, Walter

“…FGF2 is a cell survival factor involved in tumor-induced angiogenesis that is secreted through an unconventional secretory pathway based upon direct protein…”
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The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles by Trautz, Birthe, Wiedemann, Hannah, Lüchtenborg, Christian, Pierini, Virginia, Kranich, Jan, Glass, Bärbel, Kräusslich, Hans-Georg, Brocker, Thomas, Pizzato, Massimo, Ruggieri, Alessia, Brügger, Britta, Fackler, Oliver T.

“…The host-cell restriction factor SERINC5 potently suppresses the infectivity of HIV, type 1 (HIV-1) particles, and is counteracted by the viral pathogenesis…”
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Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes by Krumpe, Katrin, Frumkin, Idan, Herzig, Yonatan, Rimon, Nitzan, Özbalci, Cagakan, Brügger, Britta, Rapaport, Doron, Schuldiner, Maya

“…Tail-anchored (TA) proteins have a single C-terminal transmembrane domain, making their biogenesis dependent on posttranslational translocation. Despite their…”
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Molecular and structural architecture of polyQ aggregates in yeast by Gruber, Anselm, Hornburg, Daniel, Antonin, Matthias, Krahmer, Natalie, Collado, Javier, Schaffer, Miroslava, Zubaite, Greta, Lüchtenborg, Christian, Sachsenheimer, Timo, Brügger, Britta, Mann, Matthias, Baumeister, Wolfgang, Hartl, F. Ulrich, Hipp, Mark S., Fernández-Busnadiego, Rubén

“…Huntington’s disease is caused by the expansion of a polyglutamine (polyQ) tract in the N-terminal exon of huntingtin (HttEx1), but the cellular mechanisms…”
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Protease‐resistant streptavidin for interaction proteomics by Rafiee, Mahmoud‐Reza, Sigismondo, Gianluca, Kalxdorf, Mathias, Förster, Laura, Brügger, Britta, Béthune, Julien, Krijgsveld, Jeroen

“…Streptavidin‐mediated enrichment is a powerful strategy to identify biotinylated biomolecules and their interaction partners; however, intense…”
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EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake by Matthaeus, Claudia, Lahmann, Ines, Kunz, Séverine, Jonas, Wenke, Melo, Arthur Alves, Lehmann, Martin, Larsson, Elin, Lundmark, Richard, Kern, Matthias, Blüher, Matthias, Olschowski, Hannah, Kompa, Julian, Brügger, Britta, Müller, Dominik N., Haucke, Volker, Schürmann, Annette, Birchmeier, Carmen, Daumke, Oliver

“…Eps15-homology domain containing protein 2 (EHD2) is a dynamin-related ATPase located at the neck of caveolae, but its physiological function has remained…”
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