Search Results - "Brüggemann, Roger"

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    Pharmacokinetics and Pharmacodynamics of Posaconazole by Chen, Lu, Krekels, Elke H. J., Verweij, Paul. E., Buil, Jochem B., Knibbe, Catherijne A. J., Brüggemann, Roger J. M.

    Published in Drugs (New York, N.Y.) (01-05-2020)
    “…Posaconazole is typically used for preventing invasive yeast and mold infections such as invasive aspergillosis in high-risk immunocompromised patients. The…”
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    Journal Article
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    Cost Evaluation of Dried Blood Spot Home Sampling as Compared to Conventional Sampling for Therapeutic Drug Monitoring in Children by Martial, Lisa C, Aarnoutse, Rob E, Schreuder, Michiel F, Henriet, Stefanie S, Brüggemann, Roger J M, Joore, Manuela A

    Published in PloS one (12-12-2016)
    “…Dried blood spot (DBS) sampling for the purpose of therapeutic drug monitoring can be an attractive alternative for conventional blood sampling, especially in…”
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    Clinical Relevance of the Pharmacokinetic Interactions of Azole Antifungal Drugs with Other Coadministered Agents by Brüggemann, Roger J. M., Alffenaar, Jan-Willem C., Blijlevens, Nicole M. A., Billaud, Eliane M., Kosterink, Jos G. W., Verweij, Paul E., Burger, David M., Saravolatz, Louis D.

    Published in Clinical infectious diseases (15-05-2009)
    “…There are currently a number of licensed azole antifungal drugs; however; only 4 (namely, fluconazole, itraconazole, posaconazole, and voriconazole) are used…”
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    Efficacy of Posaconazole against Three Clinical Aspergillus fumigatus Isolates with Mutations in the cyp51A Gene by MAVRIDOU, Eleftheria, BRÜGGEMANN, Roger J. M, MELCHERS, Willem J. G, MOUTON, Johan W, VERWEIJ, Paul E

    Published in Antimicrobial Agents and Chemotherapy (01-02-2010)
    “…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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    Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature by Hartman, Stan J. F., Brüggemann, Roger J., Orriëns, Lynn, Dia, Nada, Schreuder, Michiel F., de Wildt, Saskia N.

    Published in Clinical pharmacokinetics (01-02-2020)
    “…Background Pharmacokinetics (PK) are severely altered in critically ill patients due to changes in volume of distribution (Vd) and/or drug clearance (Cl). This…”
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    Obesity and drug pharmacology: a review of the influence of obesity on pharmacokinetic and pharmacodynamic parameters by Smit, Cornelis, De Hoogd, Sjoerd, Brüggemann, Roger J M, Knibbe, Catherijne A J

    “…The rising prevalence of obesity confronts clinicians with dosing problems in the (extreme) overweight population. Obesity has a great impact on key organs…”
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    High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints by Jansen, Anouk M. E., ter Heine, Rob, Verweij, Paul E., Brüggemann, Roger J. M.

    Published in Clinical pharmacokinetics (01-12-2023)
    “…Isavuconazole exposure–response relationships have been studied with a focus on total rather than unbound exposure, assuming a constant unbound fraction of 1%…”
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    Pharmacodynamics of isavuconazole in an Aspergillus fumigatus mouse infection model by Seyedmousavi, Seyedmojtaba, Brüggemann, Roger J M, Meis, Jacques F, Melchers, Willem J G, Verweij, Paul E, Mouton, Johan W

    Published in Antimicrobial agents and chemotherapy (01-05-2015)
    “…Azole resistance is an emerging problem in Aspergillus fumigatus which translates into treatment failure. Alternative treatments with new azoles may improve…”
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    Clinical Pharmacokinetics, Pharmacodynamics, Safety and Efficacy of Liposomal Amphotericin B by Groll, Andreas H, Rijnders, Bart J A, Walsh, Thomas J, Adler-Moore, Jill, Lewis, Russell E, Brüggemann, Roger J M

    Published in Clinical infectious diseases (02-05-2019)
    “…Abstract Since its introduction in the 1990s, liposomal amphotericin B (LAmB) continues to be an important agent for the treatment of invasive fungal diseases…”
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    Tobramycin Clearance Is Best Described by Renal Function Estimates in Obese and Non-obese Individuals: Results of a Prospective Rich Sampling Pharmacokinetic Study by Smit, Cornelis, Wasmann, Roeland E., Wiezer, Marinus J., van Dongen, Hendricus P. A., Mouton, Johan W., Brüggemann, Roger J. M., Knibbe, Catherijne A. J.

    Published in Pharmaceutical research (01-08-2019)
    “…Purpose Tobramycin is an aminoglycoside antibiotic of which the 24 h exposure correlates with efficacy. Recently, we found that clearance of the aminoglycoside…”
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    Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies by Jansen, Anouk M. E., Mertens, Beatrijs, Spriet, Isabel, Verweij, Paul E., Schouten, Jeroen, Wauters, Joost, Debaveye, Yves, ter Heine, Rob, Brüggemann, Roger J. M.

    Published in Clinical pharmacokinetics (01-12-2023)
    “…Background and Objectives Isavuconazole is a broad-spectrum antifungal agent for the management of invasive fungal disease. Optimised drug exposure is critical…”
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