Search Results - "Bozzi, Y"
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Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Published in Molecular psychiatry (01-12-2021)“…Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly heterogeneous abnormalities in functional brain connectivity. However, the origin…”
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Reduced phosphorylation of synapsin I in the hippocampus of Engrailed-2 knockout mice, a model for autism spectrum disorders
Published in Neuroscience (12-02-2015)“…Highlights • Synapsin I mRNA and protein are down-regulated in the hippocampus of En2−/− mice. • Synapsin I phosphorylation is reduced in the En2−/−…”
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Correction: Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Published in Molecular psychiatry (01-09-2022)Get full text
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Brain-derived neurotrophic factor signaling is altered in the forebrain of Engrailed-2 knockout mice
Published in Neuroscience (02-06-2016)“…Highlights • BDNF mRNA and protein expression is reduced in the neocortex of En2−/− mice. • p75 receptor expression is down-regulated in the En2−/− neocortex…”
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Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility
Published in Neuroscience (07-03-2014)“…Highlights • Otx2 overexpression results in an increased number of midbrain dopaminergic DA neurons. • Otx2-overexpressing mice show increased dopamine…”
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Increased susceptibility to kainic acid–induced seizures in Engrailed - 2 knockout mice
Published in Neuroscience (17-03-2009)“…Abstract The En2 gene, coding for the homeobox-containing transcription factor Engrailed-2 (EN2), has been associated to autism spectrum disorder (ASD). Due to…”
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Acute physiological response of mammalian central neurons to axotomy: ionic regulation and electrical activity
Published in The FASEB journal (01-12-2004)“…The transection of the axon of central neurons has dramatic consequences on the damaged cells and nerves. Injury activates molecular programs leading to a…”
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Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region
Published in Neuroscience (12-02-2013)“…Highlights ► Prenatal deletion of survivin results in deteriorated hippocampal synaptic plasticity. ► SurvivinCamcre mice show impaired long-term potentiation…”
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Neuroprotective Role of Dopamine Against Hippocampal Cell Death
Published in The Journal of neuroscience (15-11-2000)“…Glutamate excitotoxicity plays a key role in the induction of neuronal cell death occurring in many neuropathologies, including epilepsy. Systemic…”
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Monocular deprivation decreases the expression of messenger RNA for brain-derived neurotrophic factor in the rat visual cortex
Published in Neuroscience (01-12-1995)“…We found that deprivation of pattern vision in one eye, that leaves luminance detection performance unaffected, is sufficient to reduce brain-derived…”
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Monocular deprivation decreases brain-derived neurotrophic factor immunoreactivity in the rat visual cortex
Published in Neuroscience (01-05-1999)“…Neurotrophins play a crucial role in the development and activity-dependent plasticity of the visual cortex [Berardi N. et al. (1994) Proc. natn. Acad. Sci…”
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Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice
Published in Behavioural brain research (10-03-2002)“…In order to assess the role of dopamine (DA) D2 and D3 receptors in the modulation of behaviour, we analysed exploration in a spatial novelty in mouse model…”
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Dopamine in neurotoxicity and neuroprotection: what do D 2 receptors have to do with it?
Published in Trends in neurosciences (Regular ed.) (01-03-2006)“…Accurate control of dopamine levels and/or the resulting dopamine–receptor interaction is essential for brain function. Indeed, several human neurological and…”
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Dopamine in neurotoxicity and neuroprotection: what do D sub(2) receptors have to do with it?
Published in Trends in neurosciences (Regular ed.) (01-03-2006)“…Accurate control of dopamine levels and/or the resulting dopamine-receptor interaction is essential for brain function. Indeed, several human neurological and…”
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15
Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility
Published in Molecular and cellular neuroscience (01-02-2008)“…In the present study, we demonstrate a direct role for d-aspartate in regulating hippocampal synaptic plasticity. These evidences were obtained using two…”
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[P2.11]: Dysfunction of GABAergic neurons in the Engrailed 2 mouse model of autism
Published in International journal of developmental neuroscience (01-12-2010)Get full text
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BoNT/E prevents seizure-induced activation of caspase 3 in the rat hippocampus
Published in Neuroreport (16-04-2007)“…Clinical and experimental studies clearly demonstrate that prolonged seizures and status epilepticus induce neuronal cell death in the brain. Recent evidence…”
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Antiepileptic Effects of Botulinum Neurotoxin E
Published in The Journal of neuroscience (23-02-2005)“…Experimental studies suggest that the delivery of antiepileptic agents into the seizure focus might be of potential utility for the treatment of focal-onset…”
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Kainic acid-induced seizures activate GSK-3[beta] in the hippocampus of D2R-/- mice
Published in Neuroreport (23-08-2010)“…Dopamine D2 receptor (D2R) signalling is implicated in limbic seizure propagation and seizure-induced neurodegeneration. D2R-/- mice display increased…”
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Antiproliferative Role of Dopamine: Loss of D 2 Receptors Causes Hormonal Dysfunction and Pituitary Hyperplasia
Published in Neuron (Cambridge, Mass.) (01-07-1997)“…The function of dopamine (DA) in the nervous system is paralleled by its neuroendocrine control of pituitary gland functions. Here, we document the…”
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