Search Results - "Bozoglu, T."

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy by Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A. B., Bozoglu, T., Baehr, A., Schneider, C. M., Sinnecker, D., Klett, K., Fröhlich, T., Rahman, F. Abdel, Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M. C., Klymiuk, N., Laugwitz, K. L., Wolf, E., Wurst, W., Kupatt, C.

“…Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients…”
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Cardiovascular risk factors in patients with aortic stenosis predict prevalence of coronary artery disease but not of aortic stenosis: an angiographic pair matched case–control study by Ortlepp, J R, Schmitz, F, Bozoglu, T, Hanrath, P, Hoffmann, R

“…Background: Traditional cardiovascular risk factors have been associated with aortic stenosis and coronary artery disease. As these two conditions often…”
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Endothelial retargeting of AAV9 in vivo by Bozoglu, T, Lee, S, Ziegler, T, Kupatt, C

“…Abstract Background Adeno-associated virus (AAV) is favorable choice for gene transfer and gene editing applications in vivo, due to its low integration rate…”
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AAV.Cas9 and AAV.SERCA2a strategies to mitigate heart failure in DMD pigs by Baehr, A, Hornaschewitz, N, Stirm, M, Hoppmann, P, Bozoglu, T, Klymiuk, N, Laugwitz, K L, Moretti, A, Wolf, E, Hajjar, R, Kupatt, C

“…Abstract Aims Duchenne muscular dystrophy is a devastating disease affecting skeletal muscle and heart, which is caused by loss-of-function mutations in the…”
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Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair by Ferraro, Bartolo, Leoni, Giovanna, Hinkel, Rabea, Ormanns, Steffen, Paulin, Nicole, Ortega-Gomez, Almudena, Viola, Joana R, de Jong, Renske, Bongiovanni, Dario, Bozoglu, Tarik, Maas, Sanne L, D'Amico, Michele, Kessler, Thorsten, Zeller, Tanja, Hristov, Michael, Reutelingsperger, Chris, Sager, Hendrik B, Döring, Yvonne, Nahrendorf, Matthias, Kupatt, Christian, Soehnlein, Oliver

“…Heart failure following myocardial infarction (MI) remains one of the major causes of death worldwide, and its treatment is a crucial challenge of…”
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Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs by Baehr, Andrea, Umansky, Kfir Baruch, Bassat, Elad, Jurisch, Victoria, Klett, Katharina, Bozoglu, Tarik, Hornaschewitz, Nadja, Solyanik, Olga, Kain, David, Ferraro, Bartolo, Cohen-Rabi, Renee, Krane, Markus, Cyran, Clemens, Soehnlein, Oliver, Laugwitz, Karl Ludwig, Hinkel, Rabea, Kupatt, Christian, Tzahor, Eldad

“…Background: Ischemic heart diseases are leading causes of death and reduced life quality worldwide. Although revascularization strategies significantly reduce…”
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Targeted overexpression of regnase-1 in the aorta prevents aneurysm growth in a murine model of Marfan syndrome by Noormalal, M, Remes, A, Schmiedel, N, Matzen, A, Hille, S, Bozoglu, T, Wolf, A, Zaradzki, M, Karck, M, Kupatt, C, Frank, D, Frey, N, Mueller, O J

“…Abstract Background/Introduction Marfan syndrome is a rare genetic disorder caused by mutations in the fibrillin-1 gene. This markedly affects the…”
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Mathematical modeling of survival and weight loss of Baker's yeast during drying by Alpas, Hami, Özilgen, Mustafa, Faruk Bozoǧlu, T., Katnas, Sinan

“…Drying and death rates of Baker's yeast were studied in a computer-controlled laboratory scale tunnel drier with varying air velocity between 2.0–3.0 ms −1 and…”
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DETECTING PORCN MICRODELETIONS IN A LARGE FAMILY WITH FOCAL DERMAL HYPOPLASIA by Seven, M, Güven, A, Bozoğlu, T M, Tolun, A

“…Focal dermal hypoplasia (FDH), an X-linked dominant disease with a highly variable phenotype, presents mainly with congenital linear pigmentation of the skin,…”
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Characterization of extracellular beta-lactamases from penicillin G-resistant cells of Streptococcus thermophilus by Chirica, L C, Güray, T, Gürakan, G C, Bozoğlu, T F

“…In this study, biochemical properties of two extracellular beta-lactamases produced by penicillin-resistant Streptococcus thermophilus cells were investigated…”
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Identification of Lactobacillus strains from Turkish-style dry fermented sausages by Gürakan, G.C., Bozoglu, T.F., Weiss, N.

“…A total of 31 strains of facultatively anaerobic, non-motile, Gram-positive, rod-shaped bacteria were isolated from different Turkish dry sausage (soudjouk)…”
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Growth kinetics of Streptococcus thermophilus at subbacteriostatic penicillin G concentrations by Yöndem, F, Ozilgen, M, Bozoglu, T F

“…Streptococcus thermophilus may be subjected to the effects of penicillin G in contaminated milk used for yogurt production. Sensitivity of this microorganism…”
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Relation of stent design and stent surface material to subsequent in-stent intimal hyperplasia in coronary arteries determined by intravascular ultrasound by Hoffmann, Rainer, Mintz, Gary S, Haager, Philipp K, Bozoglu, Togul, Grube, Eberhard, Gross, Michael, Beythien, Christian, Mudra, Harald, vom Dahl, Jürgen, Hanrath, Peter

“…A variety of different stent designs and coatings have become available. This study sought to determine the impact of stent design and gold-coating of stents…”
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Spezielle Indikation und Technik der operativen Behandlung von Verschlussprozessen an der V. cava inferior by Pillny, M., Sandmann, W., Süß, B., Bozoglu, T.

“…Zusammenfassung Störungen der Bildung der V. cava inferior (VCI) in der Embryonalzeit und Thrombosen der VCI führen sowohl zu einem akuten als auch einem…”
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Behaviour of Salmonella typhimurium in feta cheese during its manufacture and ripening by Erkmen, Osman, Faruk Bozo⩽gluce, T.

“…Salmonella typhimurium was enumerated during the manufacture and ripening period of Feta cheeses with particular reference to: (a) different inoculation levels…”
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