Can microalbuminuria be an ındicator of renal ınvolvement in pediatric Covid 19 patients?

Can microalbuminuria be an ındicator of renal ınvolvement in pediatric Covid 19 patients?

Background Proteinuria (both tubular and glomerular in origin) and its implications are well-known features of adult patients with COVID19. However currently studies addressing proteinuria and its role in the outcome of kidney and patients of pediatric COVID 19 is scarce. We aimed to evaluate the pr...

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Bibliographic Details
Published in:Infection Vol. 50; no. 3; pp. 719 - 724
Main Authors: Özlü, Sare Gülfem, Aydın, Zehra, Bozelli, Berrak Naz, Avcı, Begüm, İnözü, Mihriban, Çaycı, Fatma Şemsa, Gülhan, Belgin, Sezer, Sevilay, Bayrakçı, Umut Selda
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 01-06-2022
Springer Nature B.V
Subjects:
COVID-19
Family Medicine
Gender
General Practice
Hemoglobin
Infectious Diseases
Internal Medicine
Leukocytes
Medicine
Medicine & Public Health
Original Paper
Patients
Pediatrics
Platelets
Proteinuria
SARS-CoV-2
PNEP-D-21-00705 children, COVID 19, Kidney involvement
Microalbuminuria
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Summary:Background Proteinuria (both tubular and glomerular in origin) and its implications are well-known features of adult patients with COVID19. However currently studies addressing proteinuria and its role in the outcome of kidney and patients of pediatric COVID 19 is scarce. We aimed to evaluate the presence of microalbuminuria in order to detect early renal involvement in pediatric COVID 19 patients. Methods We prospectively evaluated 100 pediatric patients hospitalized with COVID 19 between April and July 2020. Clinical presentations, laboratory findings and outcomes were investigated. Microalbuminuria was compared with the age, gender, disease severity, and hemoglobin, platelet, leukocyte count and serum CRP levels of the patients. Results Twenty seven out of 100 patients had microalbuminuria. Fourteen patients had mild and fourteen had moderate disease. There was not any significant relation according to age and gender. Microalbuminuria was not related to the severity of the disease. Also the mean microalbuminuria level did not differ according to the disease course. Hemoglobin, platelet, leukocyte counts and serum CRP levels were also were not correlated with microalbuminuria levels. Conclusion Although there was no difference between the groups with different disease course; microalbuminuria is detected in an important ratio of pediatric patients with COVID 19 in this study. In the highlight of our findings we suggest that urinary findings of pediatric COVID patients should be carefully evaluated.
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ISSN:0300-8126
1439-0973
DOI:10.1007/s15010-021-01745-z