Search Results - "Bozdaganyan, Marine E"

Elastic Membrane Deformations Govern Interleaflet Coupling of Lipid-Ordered Domains by Galimzyanov, Timur R, Molotkovsky, Rodion J, Bozdaganyan, Marine E, Cohen, Fredric S, Pohl, Peter, Akimov, Sergey A

“…The mechanism responsible for domain registration in two membrane leaflets has thus far remained enigmatic. Using continuum elasticity theory, we show that…”
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Immune Escape Associated with RBD Omicron Mutations and SARS-CoV-2 Evolution Dynamics by Kudriavtsev, Aleksandr V, Vakhrusheva, Anna V, Novosеletsky, Valery N, Bozdaganyan, Marine E, Shaitan, Konstantin V, Kirpichnikov, Mikhail P, Sokolova, Olga S

“…The evolution and the emergence of new mutations of viruses affect their transmissibility and/or pathogenicity features, depending on different evolutionary…”
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CPE-DB: An Open Database of Chemical Penetration Enhancers by Vasyuchenko, Ekaterina P, Orekhov, Philipp S, Armeev, Grigoriy A, Bozdaganyan, Marine E

“…The cutaneous delivery route currently accounts for almost 10% of all administered drugs and it is becoming more common. Chemical penetration enhancers (CPEs)…”
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Synergistic Effect of Chemical Penetration Enhancers on Lidocaine Permeability Revealed by Coarse-Grained Molecular Dynamics Simulations by Bozdaganyan, Marine E, Orekhov, Philipp S

“…The search for new formulations for transdermal drug delivery (TDD) is an important field in medicine and cosmetology. Molecules with specific physicochemical…”
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Computational Analysis of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike and Their Effects on Antibody Binding by Bozdaganyan, Marine E, Shaitan, Konstantin V, Kirpichnikov, Mikhail P, Sokolova, Olga S, Orekhov, Philipp S

“…Currently, SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) is responsible for one of the most deleterious pandemics of our time. The interaction between…”
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Comparative computational study of interaction of C60-fullerene and tris-malonyl-C60-fullerene isomers with lipid bilayer: relation to their antioxidant effect by Bozdaganyan, Marine E, Orekhov, Philipp S, Shaytan, Alexey K, Shaitan, Konstantin V

“…Oxidative stress induced by excessive production of reactive oxygen species (ROS) has been implicated in the etiology of many human diseases. It has been…”
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Mechanisms of Formation, Structure, and Dynamics of Lipoprotein Discs Stabilized by Amphiphilic Copolymers: A Comprehensive Review by Orekhov, Philipp S, Bozdaganyan, Marine E, Voskoboynikova, Natalia, Mulkidjanian, Armen Y, Karlova, Maria G, Yudenko, Anna, Remeeva, Alina, Ryzhykau, Yury L, Gushchin, Ivan, Gordeliy, Valentin I, Sokolova, Olga S, Steinhoff, Heinz-Jürgen, Kirpichnikov, Mikhail P, Shaitan, Konstantin V

“…Amphiphilic copolymers consisting of alternating hydrophilic and hydrophobic units account for a major recent methodical breakthrough in the investigations of…”
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Colabind: A Cloud-Based Approach for Prediction of Binding Sites Using Coarse-Grained Simulations with Molecular Probes by Andreev, Georgy, Kovalenko, Max, Bozdaganyan, Marine E., Orekhov, Philipp S.

“…Binding site prediction is a crucial step in understanding protein–ligand and protein–protein interactions (PPIs) with broad implications in drug discovery and…”
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Styrene/Maleic Acid Copolymers Form SMALPs by Pulling Lipid Patches out of the Lipid Bilayer by Orekhov, Philipp S, Bozdaganyan, Marine E, Voskoboynikova, Natalia, Mulkidjanian, Armen Y, Steinhoff, Heinz-Jürgen, Shaitan, Konstantin V

“…Amphiphilic copolymers composed of styrene and maleic acid (SMA) monomers caused a major methodical breakthrough in the study of membrane proteins. They were…”
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Molecular Mechanism of Uptake of Cationic Photoantimicrobial Phthalocyanine across Bacterial Membranes Revealed by Molecular Dynamics Simulations by Orekhov, Philipp S, Kholina, Ekaterina G, Bozdaganyan, Marine E, Nesterenko, Alexey M, Kovalenko, Ilya B, Strakhovskaya, Marina G

“…Phthalocyanines are aromatic macrocyclic compounds, which are structurally related to porphyrins. In clinical practice, phthalocyanines are used in…”
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Lipid dynamics in nanoparticles formed by maleic acid-containing copolymers: EPR spectroscopy and molecular dynamics simulations by Colbasevici, Alexandr, Voskoboynikova, Natalia, Orekhov, Philipp S., Bozdaganyan, Marine E., Karlova, Maria G., Sokolova, Olga S., Klare, Johann P., Mulkidjanian, Armen Y., Shaitan, Konstantin V., Steinhoff, Heinz-Jürgen

“…Amphiphilic maleic acid-containing copolymers account for a recent methodical breakthrough in the study of membrane proteins. Their application enables a…”
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Using a viral 2A peptide-based strategy to reconstruct the bovine P450scc steroidogenic system in S. cerevisiae: Bovine P450scc system expression using 2A peptides by Efimova, Vera S, Isaeva, Ludmila V, Orekhov, Philipp S, Bozdaganyan, Marine E, Rubtsov, Mikhail A, Novikova, Ludmila A

“…Cytochrome P450scc system performs the first rate-limiting stage of steroidogenesis in mammals. The bovine P450scc system was reconstructed in Saccharomyces…”
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Proton leakage across lipid bilayers: Oxygen atoms of phospholipid ester linkers align water molecules into transmembrane water wires by Bozdaganyan, Marine E., Lokhmatikov, Alexey V., Voskoboynikova, Natalia, Cherepanov, Dmitry A., Steinhoff, Heinz-Jürgen, Shaitan, Konstantin V., Mulkidjanian, Armen Y.

“…Up to half of the cellular energy gets lost owing to membrane proton leakage. The permeability of lipid bilayers to protons is by several orders of magnitude…”
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Replicative and radiation-induced aging: a comparison of gene expression profiles by Aliper, Alexander M, Bozdaganyan, Marine E, Orekhov, Philipp S, Zhavoronkov, Alex, Osipov, Andreyan N

“…All living organisms are subject to the aging process and experience the effect of ionizing radiation throughout their life. There have been a number of…”
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Strategic aromatic residues in the catalytic cleft of the xyloglucanase MtXgh74 modifying thermostability, mode of enzyme action, and viscosity reduction ability by Berezina, Oksana V., Rykov, Sergey V., Polyakova, Angelina K., Bozdaganyan, Marine E., Sidochenko, Anna V., Baudrexl, Melanie, Schwarz, Wolfgang H., Zverlov, Vladimir V., Yarotsky, Sergey V.

“…The thermostable endo-processive xyloglucanase MtXgh74 from Myceliophthora thermophila was used to study the influence of aromatic amino acids in the catalytic…”
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Radioprotectors.org: an open database of known and predicted radioprotectors by Aliper, Alexander M, Bozdaganyan, Marine E, Sarkisova, Viktoria A, Veviorsky, Alexander P, Ozerov, Ivan V, Orekhov, Philipp S, Korzinkin, Mikhail B, Moskalev, Alexey, Zhavoronkov, Alex, Osipov, Andreyan N

“…The search for radioprotectors is an ambitious goal with many practical applications. Particularly, the improvement of human radioresistance for space is an…”
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Docking and Molecular Dynamics (MD) Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 Protein by Bozdaganyan, Marine E., Orekhov, Philipp S., Bragazzi, Nicola L., Panatto, Donatella, Amicizia, Daniela, Pechkova, Eugenia, Nicolini, Claudio, Gasparini, Roberto

“…Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is…”
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Abstract P-2: Multiscale Molecular Dynamics Simulations of the Skin Membranes as a Tool for the Interpretation of the Transmission Electron Microscopy Images by Bozdaganyan, Marine

“…Background: Human skin can inhibit chemical penetration which limits the clinical applications of transdermal drug delivery. The stratum corneum (SC) is the…”
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Using a viral 2A peptide-based strategy to reconstruct the bovine P450scc steroidogenic system in S. cerevisiae by Efimova, Vera S., Isaeva, Ludmila V., Orekhov, Philipp S., Bozdaganyan, Marine E., Rubtsov, Mikhail A., Novikova, Ludmila A.

“…[Display omitted] •P450scc system reconstructed in S. cerevisiae, using 2A‐based constructs.•The C-terminal sequence of the Adx substantially affected 2A…”
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Comparative Computational Study of Interaction of C.sub.60-Fullerene and Tris-Malonyl-C.sub.60-Fullerene Isomers with Lipid Bilayer: Relation to Their Antioxidant Effect by Bozdaganyan, Marine E, Orekhov, Philipp S, Shaytan, Alexey K, Shaitan, Konstantin V

“…Oxidative stress induced by excessive production of reactive oxygen species (ROS) has been implicated in the etiology of many human diseases. It has been…”
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