Search Results - "Boza, Pia"

FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation by Vivar, Raúl, Humeres, Claudio, Muñoz, Claudia, Boza, Pía, Bolivar, Samir, Tapia, Felipe, Lavandero, Sergio, Chiong, Mario, Diaz-Araya, Guillermo

“…Cardiac fibroblast differentiation to myofibroblast is a crucial process in the development of cardiac fibrosis and is tightly dependent on transforming growth…”
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IFN-β Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation by Bolívar, Samir, Anfossi, Renatto, Humeres, Claudio, Vivar, Raúl, Boza, Pía, Muñoz, Claudia, Pardo-Jimenez, Viviana, Olivares-Silva, Francisco, Díaz-Araya, Guillermo

“…Cardiac fibroblasts (CFs) contribute to theinflammatory response to tissue damage, secreting both pro- and anti-inflammatory cytokines and chemokines…”
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Cardiac fibroblast cytokine profiles induced by proinflammatory or profibrotic stimuli promote monocyte recruitment and modulate macrophage M1/M2 balance in vitro by Humeres, Claudio, Vivar, Raúl, Boza, Pia, Muñoz, Claudia, Bolivar, Samir, Anfossi, Renatto, Osorio, Jose Miguel, Olivares-Silva, Francisco, García, Lorena, Díaz-Araya, Guillermo

“…Abstract Macrophage polarization plays an essential role in cardiac remodeling after injury, evolving from an initial accumulation of proinflammatory M1…”
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Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression by Olivares-Silva, Francisco, Landaeta, Rodolfo, Aránguiz, Pablo, Bolivar, Samir, Humeres, Claudio, Anfossi, Renatto, Vivar, Raúl, Boza, Pía, Muñoz, Claudia, Pardo-Jiménez, Viviana, Peiró, Concepción, Sánchez-Ferrer, Carlos F., Díaz-Araya, Guillermo

“…Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such…”
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Expression and function of TLR4- induced B1R bradykinin receptor on cardiac fibroblasts by Muñoz-Rodríguez, Claudia, Fernández, Samuel, Osorio, José Miguel, Olivares, Francisco, Anfossi, Renatto, Bolivar, Samir, Humeres, Claudio, Boza, Pía, Vivar, Raúl, Pardo-Jimenez, Viviana, Hemmings, Karen E., Turner, Neil A., Díaz-Araya, Guillermo

“…Cardiac fibroblasts (CF) are key cells for maintaining extracellular matrix (ECM) protein homeostasis in the heart, and for cardiac repair through…”
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Lipopolysaccharide Activates Toll-Like Receptor 4 and Prevents Cardiac Fibroblast-to-Myofibroblast Differentiation by Bolívar, Samir, Santana, Roxana, Ayala, Pedro, Landaeta, Rodolfo, Boza, Pía, Humeres, Claudio, Vivar, Raúl, Muñoz, Claudia, Pardo, Viviana, Fernandez, Samuel, Anfossi, Renatto, Diaz-Araya, Guillermo

“…Bacterial lipopolysaccharide (LPS) is a known ligand of Toll-like receptor 4 (TLR4) which is expressed in cardiac fibroblasts (CF). Differentiation of CF to…”
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Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast by Catalán, Mabel, Smolic, Christian, Contreras, Ariel, Ayala, Pedro, Olmedo, Ivonne, Copaja, Miguel, Boza, Pía, Vivar, Raúl, Avalos, Yennifer, Lavandero, Sergio, Velarde, Victoria, Díaz-Araya, Guillermo

“…Kinins mediate their cellular effects through B1 (B1R) and B2 (B2R) receptors, and the activation of B2R reduces collagen synthesis in cardiac fibroblasts…”
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Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK–ERK pathways by Vivar, Raúl, Humeres, Claudio, Varela, Marcelo, Ayala, Pedro, Guzmán, Nancy, Olmedo, Ivonne, Catalán, Mabel, Boza, Pía, Muñoz, Claudia, Díaz Araya, Guillermo

“…Cardiac fibroblast (CF) death by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. Although IGF-1 has well-known cytoprotective…”
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Pharmacokinetic study of mycophenolic acid in pediatric kidney transplantation by Boza Fuentes, Pía, Yáñez Osorio, Dominique, Espinoza Giacomozzi, Natalie, de la Rivera Morales, Alonso, Rojo Lozano, Angélica, Delucchi Bicocchi, Angela, Salas Palma, Carolina

“…INTRODUCTIONMycophenolic acid (MPA) is among the drugs used to achieve effective immunosuppression in kid ney transplantation (KT), which is characterized by…”
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Evaluation of limited-sampling strategies to calculate AUC (0-24) and the role of CYP3A5 in Chilean pediatric kidney recipients using extended-release tacrolimus by Galvez, Carla, Boza, Pía, González, Mariluz, Hormazabal, Catalina, Encina, Marlene, Azócar, Manuel, Castañeda, Luis E, Rojo, Angélica, Ceballos, María Luisa, Krall, Paola

“…Kidney transplantation (KTx) requires immunosuppressive drugs such as Tacrolimus (TAC) which is mainly metabolized by CYP3A5. TAC is routinely monitored by…”
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CYP3A5 and UGT1A9 Polymorphisms Influence Immunosuppressive Therapy in Pediatric Kidney Transplant Recipients by Krall, Paola, Yañez, Dominique, Rojo, Angélica, Delucchi, Ángela, Córdova, Miguel, Morales, Jorge, Boza, Pía, de la Rivera, Alonso, Espinoza, Natalie, Armijo, Natalia, Castañeda, Luis E, Farfán, Mauricio J, Salas, Carolina

“…Tacrolimus (TAC) and mycophenolic acid (MPA) are the main immunosuppressive drugs used in pediatric kidney transplantation. Single nucleotide polymorphisms…”
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Angiotensin II Triggers NLRP3 Inflammasome Activation by a Ca2+ Signaling-Dependent Pathway in Rat Cardiac Fibroblast Ang-II by a Ca2+-Dependent Mechanism Triggers NLRP3 Inflammasome in CF by Espitia-Corredor, Jenaro Antonio, Boza, Pía, Espinoza-Pérez, Claudio, Lillo, José Miguel, Rimassa-Taré, Constanza, Machuca, Víctor, Osorio-Sandoval, José Miguel, Vivar, Raúl, Bolivar, Samir, Pardo-Jiménez, Viviana, Sánchez-Ferrer, Carlos Félix, Peiró, Concepción, Díaz-Araya, Guillermo

“…Angiotensin II (Ang-II) is a widely studied hypertensive, profibrotic, and pro-inflammatory peptide. In the heart, cardiac fibroblasts (CF) express type 1…”
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Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: IL-1β synthesis, secretion, and degradation by Boza, Pia, Ayala, Pedro, Vivar, Raúl, Humeres, Claudio, Cáceres, Felipe Tapia, Muñoz, Claudia, García, Lorena, Hermoso, Marcela A., Díaz-Araya, Guillermo

“…•TGF-β1 regulates TLR4 expression in cardiac fibroblast and myofibroblast.•Pro-IL-1b levels are higher in cardiac fibroblast than cardiac…”
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TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts by Catalán, Mabel, Aránguiz, Pablo, Boza, Pía, Olmedo, Ivonne, Humeres, Claudio, Vivar, Raúl, Anfossi, Renatto, Ayala, Pedro, Espinoza, Claudio, Lavandero, Sergio, Díaz-Araya, Guillermo

“…Cardiac myofibroblast (CMF) are non-muscle cardiac cells that play a crucial role in wound healing and in pathological remodeling. These cells are mainly…”
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Estudio farmacocinético del ácido micofenólico en el trasplante renal pediátrico: experiencia en el Hospital Dr. Luis Calvo Mackenna by Boza Fuentes, Pia, Yañez Osorio, Dominique, Espinoza Giacomozzi, Natalie, De la Rivera Morales, Alonso, Rojo Lozano, Angelica, Delucchi Bicocchi, Angela, Salas Palma, Carolina

“…Entre los fármacos utilizados para lograr una inmunosupresión efectiva en el trasplante renal (TR) se encuentra el ácido micofenólico (MPA), medicamento que se…”
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Estudio farmacocinético del ácido micofenólico en el trasplante renal pediátrico by Boza Fuentes, Pía, Yáñez Osorio, Dominique, Espinoza Giacomozzi, Natalie, de la Rivera Morales, Alonso, Rojo Lozano, Angélica, Delucchi Bicocchi, Angela, Salas Palma, Carolina

“…Resumen: Introducción: Entre los fármacos utilizados para lograr una inmunosupresión efectiva en el trasplante renal (TR) se encuentra el ácido micofenólico…”
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Estudio farmacocinético del ácido micofenólico en el trasplante renal pediátrico by Boza Fuentes, Pía, Yáñez Osorio, Dominique, Espinoza Giacomozzi, Natalie, de la Rivera Morales, Alonso, Rojo Lozano, Angélica, Delucchi Bicocchi, Angela, Salas Palma, Carolina

“…Resumen: Introducción: Entre los fármacos utilizados para lograr una inmunosupresión efectiva en el trasplante renal (TR) se encuentra el ácido micofenólico…”
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