Search Results - "Boys, Alexander J."

Ultraconformable cuff implants for long-term bidirectional interfacing of peripheral nerves at sub-nerve resolutions by Carnicer-Lombarte, Alejandro, Boys, Alexander J., Güemes, Amparo, Gurke, Johannes, Velasco-Bosom, Santiago, Hilton, Sam, Barone, Damiano G., Malliaras, George G.

“…Implantable devices interfacing with peripheral nerves exhibit limited longevity and resolution. Poor nerve-electrode interface quality, invasive surgical…”
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Building Scaffolds for Tubular Tissue Engineering by Boys, Alexander J, Barron, Sarah L, Tilev, Damyan, Owens, Roisin M

“…Hollow organs and tissue systems drive various functions in the body. Many of these hollow or tubular systems, such as vasculature, the intestines, and the…”
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There and Back Again: Building Systems That Integrate, Interface, and Interact with the Human Body by Boys, Alexander J.

“…Since Dr. Theodor Schwann posed the extension of Cell Theory to mammals in 1839, scientists have dreamt up ways to interface with and influence the cells…”
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Organic Bioelectronics for In Vitro Systems by Pitsalidis, Charalampos, Pappa, Anna-Maria, Boys, Alexander J, Fu, Ying, Moysidou, Chrysanthi-Maria, van Niekerk, Douglas, Saez, Janire, Savva, Achilleas, Iandolo, Donata, Owens, Róisín M

“…Bioelectronics have made strides in improving clinical diagnostics and precision medicine. The potential of bioelectronics for bidirectional interfacing with…”
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Digesting Digestion: An Educational Laboratory to Teach Students about Enzymes and the Gastrointestinal Tract by Mack, Stephanie, Barron, Sarah L., Boys, Alexander J.

“…Digestion is a fundamentally important process for an individual’s life. However, the physical process of digestion is hidden inside the body, making it…”
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Mineral Distribution Spatially Patterns Bone Marrow Stromal Cell Behavior on Monolithic Bone Scaffolds by Zhou, Hao, Boys, Alexander J., Harrod, Jordan B., Bonassar, Lawrence J., Estroff, Lara A.

“…Interfaces between soft tissue and bone are characterized by transitional gradients in composition and structure that mediate substantial changes in mechanical…”
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3D Bioelectronics with a Remodellable Matrix for Long‐Term Tissue Integration and Recording by Boys, Alexander J., Carnicer‐Lombarte, Alejandro, Güemes‐Gonzalez, Amparo, Niekerk, Douglas C., Hilton, Sam, Barone, Damiano G., Proctor, Christopher M., Owens, Róisín M., Malliaras, George G.

“…Bioelectronics hold the key for understanding and treating disease. However, achieving stable, long‐term interfaces between electronics and the body remains a…”
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Tissue‐Mimetic Supramolecular Polymer Networks for Bioelectronics by O'Neill, Stephen J.K., Huang, Zehuan, Ahmed, Mohammed H., Boys, Alexander J., Velasco‐Bosom, Santiago, Li, Jiaxuan, Owens, Róisín M., McCune, Jade A., Malliaras, George G., Scherman, Oren A.

“…Addressing the mechanical mismatch between biological tissue and traditional electronic materials remains a major challenge in bioelectronics. While rigidity…”
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Microscale strain mapping demonstrates the importance of interface slope in the mechanics of cartilage repair by Irwin, Rebecca M., Gao, Tianyu, Boys, Alexander J., Ortved, Kyla, Cohen, Itai, Bonassar, Lawrence J.

“…Achieving lateral integration of articular cartilage repair tissue with surrounding native cartilage remains a clinical challenge. Histological and bulk…”
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Measuring cellular contraction: Current progress and a future in bioelectronics by Boys, Alexander J., Owens, Róisín M.

“…Cellular contraction is a universal phenomenon that drives various processes in the body. As such, measurement of cell contractility is of great interest to…”
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Understanding the Stiff-to-Compliant Transition of the Meniscal Attachments by Spatial Correlation of Composition, Structure, and Mechanics by Boys, Alexander J, Kunitake, Jennie A. M. R, Henak, Corinne R, Cohen, Itai, Estroff, Lara A, Bonassar, Lawrence J

“…Recently, the scientific community has shown considerable interest in engineering tissues with organized compositional and structural gradients to mimic…”
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Cellular and Chemical Gradients to Engineer the Meniscus‐to‐Bone Insertion by Iannucci, Leanne E., Boys, Alexander J., McCorry, Mary Clare, Estroff, Lara A., Bonassar, Lawrence J.

“…Tissue‐engineered menisci hold promise as an alternative to allograft procedures but require a means of robust fixation to the native bone. The insertion of…”
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Introducing Engineering Design and Materials Science at an Earlier Age through Ceramic Cold Casting by Boys, Alexander J, Walsh, Mark C

“…Elementary and middle school science curricula typically focus on generating an interest in science and engineering through the use of hands-on activities that…”
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Tissue-Engineered Cochlear Fibrosis Model Links Complex Impedance to Fibrosis Formation for Cochlear Implant Patients by de Rijk, Simone R, Boys, Alexander J, Roberts, Iwan V, Jiang, Chen, Garcia, Charlotte, Owens, Róisín M, Bance, Manohar

“…Cochlear implants are a life-changing technology for those with severe sensorineural hearing loss, partially restoring hearing through direct electrical…”
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Combining TGF-β1 and Mechanical Anchoring to Enhance Collagen Fiber Formation and Alignment in Tissue-Engineered Menisci by Kim, Jongkil, Boys, Alexander J, Estroff, Lara A, Bonassar, Lawrence J

“…Recapitulating the collagen fiber structure of native menisci is one of the major challenges in the development of tissue-engineered menisci. Native collagen…”
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Organic electronic transmembrane device for hosting and monitoring 3D cell cultures by Pitsalidis, Charalampos, van Niekerk, Douglas, Moysidou, Chrysanthi-Maria, Boys, Alexander J., Withers, Aimee, Vallet, Romane, Owens, Róisín M.

“…3D cell models have made strides in the past decades in response to failures of 2D cultures to translate targets during the drug discovery process. Here, we…”
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Non-Destructive Spatial Mapping of Glycosaminoglycan Loss in Native and Degraded Articular Cartilage Using Confocal Raman Microspectroscopy by Gao, Tianyu, Boys, Alexander J., Zhao, Crystal, Chan, Kiara, Estroff, Lara A., Bonassar, Lawrence J.

“…Articular cartilage is a collagen-rich tissue that provides a smooth, lubricated surface for joints and is also responsible for load bearing during movements…”
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Top-Down Fabrication of Spatially Controlled Mineral-Gradient Scaffolds for Interfacial Tissue Engineering by Boys, Alexander J, Zhou, Hao, Harrod, Jordan B, McCorry, Mary Clare, Estroff, Lara A, Bonassar, Lawrence J

“…Materials engineering can generally be divided into “bottom-up” and “top-down” approaches, where current state-of-the-art methodologies are bottom-up, relying…”
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Interfaces: Cellular and Chemical Gradients to Engineer the Meniscus‐to‐Bone Insertion (Adv. Healthcare Mater. 7/2019) by Iannucci, Leanne E., Boys, Alexander J., McCorry, Mary Clare, Estroff, Lara A., Bonassar, Lawrence J.

“…In article number 1800806 by Lawrence J. Bonassar and co‐workers, a tissue engineered meniscal insertion is generated using compositional, cellular, and…”
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Bioelectronic interfacial matching for superior implant design by Boys, Alexander J., Keene, Scott T.

“…Bioelectronics offer unprecedented spatiotemporal resolution in medicine, opening new doors to electronic therapies and monitoring systems. However, the…”
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