Search Results - "Boynton, Dennis"

Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy by Endicott, S. Joseph, Boynton, Dennis N., Beckmann, Logan J., Miller, Richard A.

“…Chaperone-mediated autophagy (CMA) is the most selective form of lysosomal proteolysis. CMA modulates proteomic organization through selective protein…”
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Inhibition of class I PI3K enhances chaperone-mediated autophagy by Endicott, S Joseph, Ziemba, Zachary J, Beckmann, Logan J, Boynton, Dennis N, Miller, Richard A

“…Chaperone-mediated autophagy (CMA) is the most selective form of lysosomal proteolysis, where individual peptides, recognized by a consensus motif, are…”
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Lysosomal targetomics of ghr KO mice shows chaperone-mediated autophagy degrades nucleocytosolic acetyl-coA enzymes by Endicott, S. Joseph, Monovich, Alexander C., Huang, Eric L., Henry, Evelynn I., Boynton, Dennis N., Beckmann, Logan J., MacCoss, Michael J., Miller, Richard A.

“…Mice deficient in GHR (growth hormone receptor; ghr KO) have a dramatic lifespan extension and elevated levels of hepatic chaperone-mediated autophagy (CMA)…”
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Incidental discovery of metastatic renal cell carcinoma at the vaginal wall: A case report by Boynton, Dennis N., Tobert, Conrad M., Lane, Brian R., Noyes, Sabrina L., Zakhour, Mae

“…Metastasis of renal cell carcinoma (RCC) to the vaginal wall has rarely been reported in the literature. We present a case of a 48-year-old who was found to…”
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Renal Mass Biopsy is Associated With Fewer Radical Nephrectomies for Benign or Indolent Disease, Particularly for T1b Renal Masses by Boynton, Dennis N, Mirza, Mahin, Van Til, Monica, Butaney, Mohit, Noyes, Sabrina L, Seifman, Brian, Jafri, Mohammed, Ghani, Khurshid R, Rogers, Craig G, Lane, Brian R

“…How renal mass biopsy (RMB) impacts patient management with T1 renal masses (T1RM) is unclear. We explore the association between RMB and utilization of active…”
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Metastatic renal cell carcinoma in the bladder following complex partial nephrectomy: A case report by Boynton, Dennis N., Noyes, Sabrina L., Shah, Tanmay, Lane, Brian R.

“…Metastasis of renal cell carcinoma (RCC) to the bladder is rare. We present a case of a 74-year-old patient with a metachronous, solitary metastasis of RCC to…”
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MP41-06 ASSESSING UTILIZATION OF RENAL MASS BIOPSY IN THE MANAGEMENT OF T1A VS. T1B RENAL MASSES by Boynton, Dennis, Noyes, Sabrina, Mirza, Mahin, Seifman, Brian, Schervish, Edward, Butaney, Mohit, Qi, Ji, Rogers, Craig, Lane, Brian R.

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Simplified cardiovascular index may be the best comorbidity index for clinical use in prediction of mortality for renal cancer patients by Boynton, Dennis, Noyes, Sabrina L., Murali, Adharsh, Peabody, Henry, Krumm, Andrew, Singh, Karandeep, Lane, Brian R.

“…•Higher comorbidity, age, tumor size, and metastases predict mortality in RCC patients.•Comorbidity indices provide an objective measure of competing risks of…”
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Development and validation of a multicenter Cox regression model to predict all-cause mortality in patients with renal masses suspicious for renal cancer by Lane, Brian R., Cheaib, Joseph G., Boynton, Dennis, Pierorazio, Phillip, Noyes, Sabrina L., Peabody, Henry, Singla, Nirmish, Johnson, Anna, Ghani, Khurshid R., Krumm, Andrew, Singh, Karandeep

“…•Intervention and surveillance are options for patients with localized renal masses.•Determination of life expectancy is essential for informed decision-making…”
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Incidence and clinical relevance of paraneoplastic syndromes in patients with renal cell carcinoma by Moldovan, Tudor, Boynton, Dennis, Kuperus, Joshua, Parker, Jessica, Noyes, Sabrina L., Brede, Christopher M., Tobert, Conrad M., Lane, Brian R.

“…•A total of 33.1% of patients in a cohort of 851 had the presence of preoperative paraneoplastic syndromes (PNS).•PNS was significantly associated with…”
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MP51-10 FUNCTIONAL OUTCOMES IN RENAL MASS PATIENTS UNDERGOING ACTIVE SURVEILLANCE VERSUS PARTIAL NEPHRECTOMY: A PROPENSITY SCORE MATCHED ANALYSIS by Nguyen, Mimi V., Lane, Brian, Yuen, Kit L., Saitta, Cesare, Fujii, Yasuhisa, Nicaise, Edouard, Cerrato, Clara, Puri, Dhruv, Meagher, Margaret, Roberts, Jacob, Afari, Jonathan A., Patil, Dattatraya, Masaki, Kobayashi, Saito, Kazutaka, Shohei, Fukuda, Boynton, Dennis, Noyes, Sabrina, Tanaka, Hajime, Master, Viraj, Derweesh, Ithaar H., Desloges, Juan Javier

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Incidental discovery of metastatic renal cell carcinoma at the vaginal wall: A case report by Boynton, Dennis N, Tobert, Conrad M, Lane, Brian R, Noyes, Sabrina L, Zakhour, Mae

“…Metastasis of renal cell carcinoma (RCC) to the vaginal wall has rarely been reported in the literature. We present a case of a 48-year-old who was found to…”
Get full text

Metastatic renal cell carcinoma in the bladder following complex partial nephrectomy: A case report by Boynton, Dennis N, Noyes, Sabrina L, Shah, Tanmay, Lane, Brian R

Get full text