Search Results - "Boyle, Tom"
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Specific roles for the GATA transcription factors end-1 and end-3 during C. elegans E-lineage development
Published in Developmental biology (15-10-2011)“…end-1 and end-3 are GATA transcription factors important for specifying endoderm cell fate in Caenorhabditis elegans. Deletion of both factors together results…”
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Principles for the selection and integration of educational multimedia materials
Published in Research in learning technology (30-12-2011)“…A variety of educational multimedia resources, varying in both type and quality, is now available. The course tutor faces the problem of how to evaluate…”
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Introduction to JIME special Issue on Open Educational Resources (OER)
Published in Journal of interactive media in education : JiME (08-12-2010)“…The OER10 Conference at the University of Cambridge in March 2010 brought together many leading researchers and developers of open educational resources. This…”
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Online interactivity: best practice based on two case studies
Published in Research in learning technology (30-12-2011)“…This paper compares the experiences of two studies in the use of network supported collaborative learning. These studies aimed to enhance the learning…”
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The distributed development of quality courses for a virtual university
Published in Research in learning technology (30-12-2011)“…The perceived need for global competition in higher education has led to the proliferation of projects and initiatives focused on the development of online…”
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A Dialogue and Social Software Perspective on Deep Learning Design
Published in Journal of interactive media in education : JiME (01-01-2010)“…This article considers projects in Technology Enhanced Learning (TEL) that have focussed on designing digital tools that stimulate and support dialogue rich…”
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Layered learning design: Towards an integration of learning design and learning object perspectives
Published in Computers and education (01-04-2010)“…The use of ICT to enhance teaching and learning depends on effective design, which operates at many levels of granularity from the small to the very large…”
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Dimensions of Culturally Sensitive Factors in the Design and Development of Learning Objects
Published in Journal of interactive media in education : JiME (01-01-2010)“…Open educational resources (OERs) are designed to be globally reusable. Yet comparatively little attention has been given to the cultural issues. This paper…”
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Context and deep learning design
Published in Computers and education (01-12-2012)“…Conceptual clarification is essential if we are to establish a stable and deep discipline of technology enhanced learning. The technology is alluring; this can…”
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Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis
Published in Genome biology (01-01-2005)“…DNA methylation occurs at preferred sites in eukaryotes. In Arabidopsis, DNA cytosine methylation is maintained by three subfamilies of methyltransferases with…”
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Design principles for authoring dynamic, reusable learning objects
Published in Australasian Journal of Educational Technology (17-03-2003)“…The aim of this paper is to delineate a coherent framework for the authoring of re-purposable learning objects. The approach is orthogonal to the considerable…”
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Towards a Theoretical Base for Educational Multimedia Design
Published in Journal of interactive media in education : JiME (25-07-2002)“…The aim of this paper is to contribute to the construction of a systematic theoretical base for educational multimedia design. The paper delineates different…”
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Understanding and using technological affordances: a commentary on Conole and Dyke
Published in Research in learning technology (01-12-2004)“…The paper by Conole and Dyke sets the context by pointing to a number of problems that inhibit the widespread, effective use of Information and Communication…”
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Towards a user-oriented analytical approach to learning design
Published in Research in learning technology (01-12-2008)“…The London Pedagogy Planner (LPP) is a prototype for a collaborative online planning and design tool that supports lecturers in developing, analysing and…”
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High school students and human source material
Published in ACS Chemical Health & Safety. (01-05-2013)Get full text
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Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity
Published in Journal of medicinal chemistry (07-09-2006)“…Cyclin dependent kinases are a key family of kinases involved in cell cycle regulation and are an attractive target for cancer chemotherapy. The roles of four…”
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Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: Synthesis and structure–activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors
Published in Bioorganic & medicinal chemistry letters (15-05-2006)“…The discovery and SAR of a novel subseries of 4-anilinoquinazoline EGFR inhibitors substituted at the C-6 position with carbon-linked side chains are…”
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Case studies in Institutional Biosafety Committee application review
Published in ACS Chemical Health & Safety. (01-05-2013)Get full text
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Paradoxical activation of Raf by a novel Raf inhibitor
Published in Chemistry & biology (01-08-1999)“…Raf is a proto-oncogene that is activated in response to growth factors or phorbol esters, and is thought to activate MAP kinase kinase-1 (MKK1) and hence the…”
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The Design, Development, and Use of Multimedia Learning Objects
Published in Journal of educational multimedia and hypermedia (22-12-2004)“…This paper concerns the development and use of learning objects to address a real and urgent educational problem--the teaching and learning of introductory…”
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