Search Results - "Boyle, Joshua William"
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1
Gold-Catalyzed Sequential Cyclization of 1-En-3,9-Diyne Esters to Partially Hydrogenated 3H-Dicyclopenta[a,b]naphthalenes
Published in Chemistry : a European journal (04-05-2016)“…A synthetic method that relies on a gold(I)‐catalyzed cycloisomerization of 1‐en‐3,9‐diyne esters to spiro[4.4]non‐2‐ene‐substituted 1,2‐dihydronaphthalenes is…”
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Journal Article -
2
Aurone derivatives as Vps34 inhibitors that modulate autophagy
Published in Acta pharmaceutica Sinica. B (01-05-2019)“…We report in this study the identification of a natural product-like antagonist ( ) of Vps34 as a potent autophagy modulator structure-based virtual screening…”
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Journal Article -
3
Gold‐Catalyzed Sequential Cyclization of 1‐En‐3,9‐Diyne Esters to Partially Hydrogenated 3 H ‐Dicyclopenta[ a , b ]naphthalenes
Published in Chemistry : a European journal (04-05-2016)“…A synthetic method that relies on a gold(I)‐catalyzed cycloisomerization of 1‐en‐3,9‐diyne esters to spiro[4.4]non‐2‐ene‐substituted 1,2‐dihydronaphthalenes is…”
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Journal Article -
4
Structure-based screening and optimization of cytisine derivatives as inhibitors of the menin-MLL interaction
Published in Chemical communications (Cambridge, England) (30-04-2016)“…The natural product-like compound 1 was identified as a direct inhibitor of the menin-MLL interaction by in silico screening. Structure-based optimization…”
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Journal Article -
5
Copper-Mediated Cross-Dehydrogenative Coupling of 2-Methylpyridine and 8-Methylquinoline with Methyl Ketones and Benzamides
Published in Chemistry, an Asian journal (04-02-2016)“…A synthetic method to prepare (E)‐(pyridin‐2‐yl)enones and (E)‐(quinolin‐8‐yl)enones that relies on the respective copper(I)‐catalyzed formal…”
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Journal Article -
6
Silver-Catalyzed 1,3-Acyloxy Migration/Diels–Alder Reaction of 1,9-Dien-4-yne Esters to Partially Hydrogenated Isoquinolines
Published in Journal of organic chemistry (17-03-2017)“…A synthetic method to prepare partially hydrogenated isoquinolines efficiently from silver-mediated [3,3]-sigmatropic rearrangement/Diels–Alder reaction of…”
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Journal Article -
7
A unified approach to carbocyclic frameworks: DTDA sequences in total synthesis
Published 01-01-2015“…[3]Dendralene is a small πrich hydrocarbon that is capable of taking part in a wide range of chemical reactions, not least of which is the diene transmissive…”
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Dissertation