Search Results - "Boyko, Alex"

Epigenetic control of plant stress response by Boyko, Alex, Kovalchuk, Igor

“…Living organisms have the clearly defined strategies of stress response. These strategies are predefined by a genetic make-up of the organism and depend on a…”
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Genetic and Epigenetic Effects of Plant-Pathogen Interactions： An Evolutionary Perspective by Boyko, Alex, Kovalchuk, Igor

“…Recent reports suggest that exposure to stress is capable of influencing the frequency and pattern of inherited changes in various parts of the genome. In this…”
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Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins by Boyko, Alex, Blevins, Todd, Yao, Youli, Golubov, Andrey, Bilichak, Andriy, Ilnytskyy, Yaroslav, Hollunder, Jens, Hollander, Jens, Meins, Jr, Frederick, Kovalchuk, Igor

“…Epigenetic states and certain environmental responses in mammals and seed plants can persist in the next sexual generation. These transgenerational effects…”
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Transgenerational response to stress in Arabidopsis thaliana by Boyko, Alex, Kovalchuk, Igor

“…Plants exposed to stress pass the memory of exposure to stress to the progeny. Previously, we showed that the phenomenon of transgenerational memory of stress…”
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Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo by Koturbash, Igor, Boyko, Alex, Rodriguez-Juarez, Rocio, McDonald, Robert J., Tryndyak, Volodymyr P., Kovalchuk, Igor, Pogribny, Igor P., Kovalchuk, Olga

“…Radiation therapy is a primary treatment modality for brain tumors, yet it has been linked to the increased incidence of secondary, post-radiation therapy…”
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Potassium chloride and rare earth elements improve plant growth and increase the frequency of the Agrobacterium tumefaciens-mediated plant transformation by Boyko, Alex, Matsuoka, Aki, Kovalchuk, Igor

“…Plant transformation efficiency depends on the ability of the transgene to successfully interact with plant host factors. Our previous work and the work of…”
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Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure by Pogribny, Igor P, Tryndyak, Volodymyr P, Boyko, Alex, Rodriguez-Juarez, Rocio, Beland, Frederick A, Kovalchuk, Olga

“…Micro RNAs (miRNAs) are small non-coding RNA molecules that function as negative regulators of gene expression. They play a crucial role in the regulation of…”
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Estrogen-Induced Rat Breast Carcinogenesis is Characterized by Alterations in DNA Methylation, Histone Modifications, and Aberrant microRNA Expression by Kovalchuk, Olga, Tryndyak, Volodymyr P., Montgomery, Beverly, Boyko, Alex, Kutanzi, Kristy, Zemp, Franz, Warbritton, Alan R., Latendresse, John R., Kovalchuk, Igor, Beland, Frederick A., Pogribny, Igor P.

“…Breast cancer is the most common malignancy in women continuing to rise worldwide. Breast cancer emerges through a multi-step process, encompassing progressive…”
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Genome instability and epigenetic modification — heritable responses to environmental stress? by Boyko, Alex, Kovalchuk, Igor

“…► Exposure to stress leads to transgenerational and heritable changes. ► These changes include genome destabilization and increased stress tolerance. ► The…”
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Increase of homologous recombination frequency in vascular tissue of Arabidopsis plants exposed to salt stress by Boyko, A.(University of Lethbridge (Canada)), Hudson, D, Bhomkar, P, Kathiria, P, Kovalchuk, I

“…Here we analyzed the influence of salt stress on plant genome stability. Homologous recombination events were detected in transgenic Arabidopsis plants that…”
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Chlorine Ions but not Sodium Ions Alter Genome Stability of Arabidopsis thaliana by Boyko, Alex, Golubov, Andrey, Bilichak, Andriy, Kovalchuk, Igor

“…Various environmental stresses influence plant genome stability. Most of these stresses, such as ionizing radiation, heavy metals and organic chemicals,…”
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Genome instability and epigenetic modification — heritable responses to environmental stress?: Physiology and metabolism by BOYKO, Alex, KOVALCHUK, Igor

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Microsatellite Instability in Arabidopsis Increases with Plant Development by Golubov, Andrey, Yao, Youli, Maheshwari, Priti, Bilichak, Andriy, Boyko, Alex, Belzile, François, Kovalchuk, Igor

“…Plant development consists of the initial phase of intensive cell division followed by continuous genome endoreduplication, cell growth, and elongation. The…”
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High frequency Agrobacterium tumefaciens-mediated plant transformation induced by ammonium nitrate by Boyko, Alex, Matsuoka, Aki, Kovalchuk, Igor

“…Success in plant genetic transformation depends on the efficiency of explant regeneration and transgene integration. Whereas the former one depends on explant…”
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Epigenetic Control of Plant Stress Response: Epigenetic Research Sheds New Light on the Nature of Interactions Between Organisms and Their Environment by BOYKO, Alex, KOVALCHUK, Igor

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Detection of changes in global genome methylation using the cytosine-extension assay by Boyko, Alex, Kovalchuk, Igor

“…Methylation is a reversible covalent chemical modification of DNA intended to regulate gene expression, genome stability, and chromatin structure. Although…”
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Transgenerational response to stress in Arabidopsis thaliana by Boyko, Alex, Kovalchuk, Igor

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Analysis of locus-specific changes in methylation patterns using a COBRA (combined bisulfite restriction analysis) assay by Boyko, Alex, Kovalchuk, Igor

“…DNA methylation is a major mechanism for the reversible control of gene expression, chromatin structure, and genome stability. Methylation analysis at a given…”
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Detection and quantification of DNA strand breaks using the ROPS (random oligonucleotide primed synthesis) assay by Boyko, Alex, Kovalchuk, Igor

“…DNA double strand breaks (DSBs) arise from spontaneous DNA damage due to metabolic activities or from direct and indirect damaging effects of stress. DSBs are…”
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Acute but not chronic exposure to abiotic stress results in transient reduction of expression levels of the transgene driven by the 35S promoter by Boyko, Alex, Molinier, Jean, Chatter, Waine, Laroche, André, Kovalchuk, Igor

“…The transgenic plant performance depends on the stable expression of the integrated transgene. In this paper, we have analyzed the stability of the most…”
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