Search Results - "Boyer, Mark A"
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Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome
Published in Proceedings of the National Academy of Sciences - PNAS (12-12-2017)“…Inflammasomes are cytosolic multiprotein complexes that initiate host defense against bacterial pathogens by activating caspase-1–dependent cytokine secretion…”
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Beyond Badger’s Rule: The Origins and Generality of the Structure–Spectra Relationship of Aqueous Hydrogen Bonds
Published in The journal of physical chemistry letters (07-03-2019)“…The structure of hydrogen bonded networks is intimately intertwined with their dynamics. Despite the incredibly wide range of hydrogen bond strengths…”
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Age-related differences in IL-1 signaling and capsule serotype affect persistence of Streptococcus pneumoniae colonization
Published in PLoS pathogens (01-10-2018)“…Young age is a risk factor for prolonged colonization by common pathogens residing in their upper respiratory tract (URT). Why children present with more…”
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Neutrophils and Ly6Chi monocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection
Published in PLoS pathogens (01-04-2017)“…Early responses mounted by both tissue-resident and recruited innate immune cells are essential for host defense against bacterial pathogens. In particular,…”
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Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation
Published in Cell host & microbe (11-11-2020)“…Alveolar macrophages are among the first immune cells that respond to inhaled pathogens. However, numerous pathogens block macrophage-intrinsic immune…”
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Exploring Expansions of the Potential and Dipole Surfaces Used for Vibrational Perturbation Theory
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (13-10-2022)“…A scheme for evaluating expansions of the potential and dipole moment surfaces for vibrational perturbation theory is described. The approach is based on…”
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Prediction of Land Use Change in Long Island Sound Watersheds Using Nighttime Light Data
Published in Land (Basel) (01-12-2016)“…The Long Island Sound Watersheds (LISW) are experiencing significant land use/cover change (LUCC), which affects the environment and ecosystems in the…”
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Investigating Intramolecular H Atom Transfer Dynamics in β-Diketones with Ultrafast Infrared Spectroscopies and Theoretical Modeling
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (09-11-2023)“…The vibrational signatures and ultrafast dynamics of the intramolecular H-bond in a series of β-diketones are investigated with 2D IR spectroscopy and…”
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Characterization of the Oxazolone and Macrocyclic Motifs in the bn (n = 2-5) Product Ions from Collision-Induced Dissociation of Protonated Oligoglycine Peptides with Isomer-Selective, Cryogenic Vibrational Spectroscopy
Published in Journal of the American Society for Mass Spectrometry (07-02-2024)“…Collision-induced dissociation (CID) of small, protonated peptides leads to the formation of b-type fragment ions that can occur with several structural motifs…”
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Fast Near Ab Initio Potential Energy Surfaces Using Machine Learning
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (30-06-2022)“…A machine-learning based approach for evaluating potential energies for quantum mechanical studies of properties of the ground and excited vibrational states…”
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High-Resolution Photoelectron Spectroscopy of Vibrationally Excited Vinoxide Anions
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (13-04-2023)“…High-resolution photoelectron spectra of vibrationally pre-excited vinoxide anions (CH2CHO–) are reported using the recently developed IR-cryo-SEVI technique…”
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Diffusion Monte Carlo Studies on the Detection of Structural Changes in the Water Hexamer upon Isotopic Substitution
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (27-08-2020)“…The ground-state structures of water hexamer and several deuterated variants are studied by using the diffusion Monte Carlo (DMC) method. We demonstrate that a…”
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Direct Probe of Vibrational Fingerprint and Combination Band Coupling
Published in The journal of physical chemistry letters (11-04-2024)“…Vibrational fingerprints and combination bands are a direct measure of couplings that control molecular properties. However, most combination bands possess…”
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Characterization of the Oxazolone and Macrocyclic Motifs in the b n (n = 2–5) Product Ions from Collision-Induced Dissociation of Protonated Oligoglycine Peptides with Isomer-Selective, Cryogenic Vibrational Spectroscopy
Published in Journal of the American Society for Mass Spectrometry (07-02-2024)“…Collision-induced dissociation (CID) of small, protonated peptides leads to the formation of b-type fragment ions that can occur with several structural motifs…”
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The climate adaptation imperative: local choices targeting global problems?
Published in Local environment (02-01-2017)“…When confronted with the demands of global climate change, what causes some policy-makers to move the climate adaptation agenda forward in their communities,…”
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Climate security in the Northern Mediterranean: Threat scenarios and the prospects for resiliency
Published in Journal of regional security (2023)“…Climate change is transforming everyday around the world. From how we live our daily lives to how we grow our food, where we can build our homes, and even how…”
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Preparation and Characterization of the Halogen-Bonding Motif in the Isolated Cl–·IOH Complex with Cryogenic Ion Vibrational Spectroscopy
Published in The journal of physical chemistry letters (31-03-2022)“…In the presence of a halide ion, hypohalous acids can adopt two binding motifs upon formation of the ion–molecule complexes [XHOY]− (X, Y = Cl, Br, I): a…”
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The Role of Tunneling in the Spectra of H 5 + and D 5 + up to 7300 cm -1
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (04-06-2020)“…The spectra for H and D are extended to cover the region between 4830 and 7300 cm . These spectra are obtained using mass-selected photodissociation…”
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Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse Macrophages
Published in Infection and immunity (01-04-2016)“…Coxiella burnetii replicates within permissive host cells by employing a Dot/Icm type IV secretion system (T4SS) to translocate effector proteins that direct…”
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