Search Results - "Boyer, G."

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart by Fu, Xing, Khalil, Hadi, Kanisicak, Onur, Boyer, Justin G, Vagnozzi, Ronald J, Maliken, Bryan D, Sargent, Michelle A, Prasad, Vikram, Valiente-Alandi, Iñigo, Blaxall, Burns C, Molkentin, Jeffery D

“…Fibroblasts are a dynamic cell type that achieve selective differentiated states to mediate acute wound healing and long-term tissue remodeling with scarring…”
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Extinctions and the loss of ecological function in island bird communities by Boyer, Alison G, Jetz, Walter

“…AIM: Because of the negative impact that ongoing biodiversity loss may have on ecosystem properties that are critical for humans, understanding the…”
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Magnitude and variation of prehistoric bird extinctions in the Pacific by Duncan, Richard P., Boyer, Alison G., Blackburn, Tim M.

“…The largest extinction event in the Holocene occurred on Pacific islands, where Late Quaternary fossils reveal the loss of thousands of bird populations…”
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Drivers and hotspots of extinction risk in marine mammals by Davidson, Ana D, Boyer, Alison G, Kim, Hwahwan, Pompa-Mansilla, Sandra, Hamilton, Marcus J, Costa, Daniel P, Ceballos, Gerardo, Brown, James H

“…The world's oceans are undergoing profound changes as a result of human activities. However, the consequences of escalating human impacts on marine mammal…”
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Selective Serotonin Reuptake Inhibitors and Adverse Effects: A Narrative Review by Edinoff, Amber N., Akuly, Haseeb A., Hanna, Tony A., Ochoa, Carolina O., Patti, Shelby J., Ghaffar, Yahya A., Kaye, Alan D., Viswanath, Omar, Urits, Ivan, Boyer, Andrea G., Cornett, Elyse M., Kaye, Adam M.

“…Depression is the most prevalent psychiatric disorder in the world, affecting 4.4% of the global population. Despite an array of treatment modalities,…”
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MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs by Wang, Lu, Zeng, Hao, Wang, Qiang, Zhao, Zibo, Boyer, Thomas G, Bian, Xiuwu, Xu, Wei

“…The RNA polymerase II mediator complex subunit 12 (MED12) is frequently mutated in human cancers, and loss of MED12 has been shown to induce drug resistance…”
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Quantification of Toxic Microcystis spp. during the 2003 and 2004 Blooms in Western Lake Erie using Quantitative Real-Time PCR by Rinta-Kanto, J. M, Ouellette, A. J. A, Boyer, G. L, Twiss, M. R, Bridgeman, T. B, Wilhelm, S. W

“…In August of 2003 and August of 2004, blooms of potentially toxic cyanobacteria Microcystis spp. persisted in western Lake Erie. Samples collected from the…”
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Chicken Manure Biochar as Liming and Nutrient Source for Acid Appalachian Soil by Hass, Amir, Gonzalez, Javier M., Lima, Isabel M., Godwin, Harry W., Halvorson, Jonathan J., Boyer, Douglas G.

“…Acid weathered soils often require lime and fertilizer application to overcome nutrient deficiencies and metal toxicity to increase soil productivity…”
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Multiple ecological pathways to extinction in mammals by Davidson, Ana D, Hamilton, Marcus J, Boyer, Alison G, Brown, James H, Ceballos, Gerardo

“…As human population and resource demands continue to grow, biodiversity conservation has never been more critical. About one-quarter of all mammals are in…”
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Consistent Ecological Selectivity through Time in Pacific Island Avian Extinctions by BOYER, ALISON G.

“…Understanding the ecological mechanisms that lead to extinction is a central goal of conservation. Can understanding ancient avian extinctions help to predict…”
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Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity by Turunen, Mikko, Spaeth, Jason M., Keskitalo, Salla, Park, Min Ju, Kivioja, Teemu, Clark, Alison D., Mäkinen, Netta, Gao, Fangjian, Palin, Kimmo, Nurkkala, Helka, Vähärautio, Anna, Aavikko, Mervi, Kämpjärvi, Kati, Vahteristo, Pia, Kim, Chongwoo A., Aaltonen, Lauri A., Varjosalo, Markku, Taipale, Jussi, Boyer, Thomas G.

“…Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit MED12 occur at very high frequency (∼70%) in uterine leiomyomas. However,…”
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Long-term trends and causal factors associated with Microcystis abundance and toxicity in San Francisco Estuary and implications for climate change impacts by Lehman, P. W., Marr, K., Boyer, G. L., Acuna, S., Teh, S. J.

“…The impacts of climate change on Microcystis blooms in San Francisco Estuary are uncertain because factors associated with the abundance and distribution of…”
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Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy by Boyer, Justin G., Huo, Jiuzhou, Han, Sarah, Havens, Julian R., Prasad, Vikram, Lin, Brian L., Kass, David A., Song, Taejeong, Sadayappan, Sakthivel, Khairallah, Ramzi J., Ward, Christopher W., Molkentin, Jeffery D.

“…Skeletal muscle can repair and regenerate due to resident stem cells known as satellite cells. The muscular dystrophies are progressive muscle wasting diseases…”
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Aberrant R-loop-induced replication stress in MED12-mutant uterine fibroids by Muralimanoharan, Sribalasubashini, Shamby, Ross, Stansbury, Nicholas, Schenken, Robert, de la Pena Avalos, Barbara, Javanmardi, Samin, Dray, Eloise, Sung, Patrick, Boyer, Thomas G.

“…Uterine fibroid (UF) driver mutations in Mediator complex subunit 12 (MED12) trigger genomic instability and tumor development through unknown mechanisms…”
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Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells by Yang, Qiwei, Vafaei, Somayeh, Falahati, Ali, Khosh, Azad, Bariani, Maria Victoria, Omran, Mervat M, Bai, Tao, Siblini, Hiba, Ali, Mohamed, He, Chuan, Boyer, Thomas G, Al-Hendy, Ayman

“…Bromodomain-containing proteins (BRDs) are involved in many biological processes, most notably epigenetic regulation of transcription, and BRD dysfunction has…”
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Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy by Bowerman, Melissa, Murray, Lyndsay M, Boyer, Justin G, Anderson, Carrie L, Kothary, Rashmi

“…Spinal muscular atrophy (SMA) is the leading genetic cause of infant death. It is caused by mutations/deletions of the survival motor neuron 1 (SMN1) gene and…”
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Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19 by Park, Min Ju, Shen, Hailian, Spaeth, Jason M., Tolvanen, Jaana H., Failor, Courtney, Knudtson, Jennifer F., McLaughlin, Jessica, Halder, Sunil K., Yang, Qiwei, Bulun, Serdar E., Al-Hendy, Ayman, Schenken, Robert S., Aaltonen, Lauri A., Boyer, Thomas G.

“…Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit MED12 occur at high frequency in uterine fibroids (UFs) and breast…”
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CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF by Dannappel, Marius V, Zhu, Danxi, Sun, Xin, Chua, Hui Kheng, Poppelaars, Marle, Suehiro, Monica, Khadka, Subash, Lim Kam Sian, Terry Cc, Sooraj, Dhanya, Loi, Melissa, Gao, Hugh, Croagh, Daniel, Daly, Roger J, Faridi, Pouya, Boyer, Thomas G, Firestein, Ron

“…Initiation and maintenance of transcriptional states are critical for controlling normal tissue homeostasis and differentiation. The cyclin dependent kinases…”
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Initial impacts of Microcystis aeruginosa blooms on the aquatic food web in the San Francisco Estuary by Lehman, P. W, Teh, S. J, Boyer, G. L, Nobriga, M. L, Bass, E, Hogle, C

“…The impact of the toxic cyanobacterium Microcystis aeruginosa on estuarine food web production in San Francisco Estuary is unknown. It is hypothesized that…”
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Evolution of Maximum Body Size of Terrestrial Mammals by Smith, Felisa A, Boyer, Alison G, Brown, James H, Costa, Daniel P, Dayan, Tamar, Ernest, S.K. Morgan, Evans, Alistair R, Fortelius, Mikael, Gittleman, John L, Hamilton, Marcus J, Harding, Larisa E, Lintulaakso, Kari, Lyons, S. Kathleen, McCain, Christy, Okie, Jordan G, Saarinen, Juha J, Sibly, Richard M, Stephens, Patrick R, Theodor, Jessica, Uhen, Mark D

“…The extinction of dinosaurs at the Cretaceous/Paleogene (K/Pg) boundary was the seminal event that opened the door for the subsequent diversification of…”
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