Search Results - "Boyd, Brooks"

Effect of Hepatic Impairment on the Pharmacokinetics of Fenfluramine and Norfenfluramine by Mittur, Aravind, Madanick, Ryan, Langlois, Melanie, Boyd, Brooks

“…Fenfluramine (Fintepla®) is approved for the treatment of seizures associated with the rare epileptic encephalopathies Dravet syndrome and Lennox–Gastaut…”
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The Lack of Effect of Food on the Pharmacokinetics of ZX008 (Fenfluramine Oral Solution): Results of a Single-dose, Two-period Crossover Study by Gammaitoni, Arnold, Smith, Steven, Boyd, Brooks

“…Fenfluramine is being developed as a low-dose adjunctive treatment for seizures in patients with Dravet syndrome and other epileptic encephalopathies,…”
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A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects by Boyd, Brooks, Smith, Steven, Gammaitoni, Arnold, Galer, Bradley S, Farfel, Gail M

“…Phase I, open-label, randomized, single-dose, 3-period crossover study assessing pharmacokinetics (PK) and safety of ZX008, a liquid oral formulation of…”
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In vitro evaluation suggests fenfluramine and norfenfluramine are unlikely to act as perpetrators of drug interactions by Martin, Parthena, Czerwiński, Maciej, Limaye, Pallavi B., Ogilvie, Brian W., Smith, Steven, Boyd, Brooks

“…Studies support the safety and efficacy of fenfluramine (FFA) as an antiseizure medication (ASM) in Dravet syndrome, Lennox‐Gastaut syndrome, or CDKL5…”
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In vitro evaluation of fenfluramine and norfenfluramine as victims of drug interactions by Martin, Parthena, Czerwiński, Maciej, Limaye, Pallavi B., Muranjan, Seema, Ogilvie, Brian W., Smith, Steven, Boyd, Brooks

“…Fenfluramine (FFA) has potent antiseizure activity in severe, pharmacoresistant childhood‐onset developmental and epileptic encephalopathies (e.g., Dravet…”
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The effects of system parameters on in vivo injection performance of a needle-free injector in human volunteers by LINN, Lawrence, BOYD, Brooks, IONTCHEV, Hristo, KING, Toby, FARR, Stephen J

“…For a novel needle-free injection (NFI) system, the relationship between frequency of wet or incomplete injections and device-related factors and subject…”
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The stability of recombinant human growth hormone in poly(lactic-co-glycolic acid) (PLGA) microspheres by CLELAND, J. L, MAC, A, JONES, A. J. S, BOYD, B, YANG, J, DUENAS, E. T, YEUNG, D, BROOKS, D, HSU, C, CHU, H, MUKKU, V

“…The development of a sustained release formulation for recombinant human growth hormone (rhGH) as well as other proteins requires that the protein be stable at…”
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Fenfluramine modulates the anti-amnesic effects induced by sigma-1 receptor agonists and neuro(active)steroids in vivo by Martin, Parthena, Maurice, Tangui, Gammaitoni, Arnold, Farfel, Gail, Boyd, Brooks, Galer, Bradley

“…•The anticonvulsant Fenfluramine and its (+)-isomer modulate the sigma-1 receptor.•Fenfluramine or (+)-Fenfluramine synergize with neurosteroids.•Progesterone…”
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Effect of gender and device mouthpiece shape on bolus insulin aerosol delivery using the AERx pulmonary delivery system by Boyd, Brooks, Noymer, Peter, Liu, Kui, Okikawa, Jerry, Hasegawa, Dave, Warren, Simon, Taylor, Glyn, Ferguson, Elizabeth, Schuster, Jeff, Farr, Stephen, Gonda, Igor

“…A study was designed to compare differences in insulin aerosol deposition profiles in healthy male and female subjects, as well as examine the effect of…”
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Recombinant human growth hormone poly(lactic-co-glycolic acid) (PLGA) microspheres provide a long lasting effect by Cleland, Jeffrey L, Duenas, Eileen, Daugherty, Ann, Marian, Melinda, Yang, Janet, Wilson, Mark, Celniker, Abigail C, Shahzamani, Azin, Quarmby, Valerie, Chu, Herman, Mukku, Venkat, Mac, Anne, Roussakis, Melissa, Gillette, Nancy, Boyd, Brooks, Yeung, Douglas, Brooks, Dennis, Maa, Yu-Fun, Hsu, Chung, Jones, Andrew J.S

“…The treatment of growth hormone deficiency requires the daily administration of recombinant human growth hormone (rhGH). Long lasting formulations of rhGH have…”
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663. An Examination of the Mechanism of Action of Fenfluramine in Dravet Syndrome: A Look beyond Serotonin by Martin, Parthena, Gammaitoni, Arnold, Farfel, Gail, Boyd, Brooks, Galer, Brad

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An Examination of the Mechanism of Action of Fenfluramine in Dravet Syndrome: A Look beyond Serotonin by Martin, Parthena, Gammaitoni, Arnold, Farfel, Gail, Boyd, Brooks, Galer, Brad

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Effect of Gender and Device Mouthpiece Shape on Bolus Insulin Aerosol Delivery Using the AER x Pulmonary Delivery System by Boyd, Brooks, Noymer, Peter, Liu, Kui, Okikawa, Jerry, Hasegawa, Dave, Warren, Simon, Taylor, Glyn, Ferguson, Elizabeth, Schuster, Jeff, Farr, Stephen, Gonda, Igor

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Watering Environmental History's Roots by Brooks, Karl Boyd

“…Environmental historians, seeking a fuller treatment of federal water-quality law's postwar evolution than Richard Lazarus's and Richard N. L. Andrews's…”
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High-frequency alternating-crossed-field gel electrophoresis with neutral or slightly charged interpenetrating networks to improve DNA separation by Boyd, B M, Prausnitz, J M, Blanch, H W

“…Toward improving DNA separations, this work reports the effects of high-frequency square-wave AC fields superimposed perpendicular to the direct current (DC)…”
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High-frequency alternating-crossed-field gel electrophoresis for DNA separation by Boyd, Brooks Matthew

“…Toward improving DNA separation, this work reports the effects of high-frequency square-wave AC electric fields superimposed perpendicular to a DC separation…”
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Unplugging the New Deal: Hells Canyon High Dam and the postwar Northwest by Brooks, Karl Boyd

“…This dissertation explores why the federal government did not build the world's largest power dam—Hells Canyon High Dam, on the Snake River in the Pacific…”
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Watering Environmental History's Roots by Brooks, Karl Boyd

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Public Power, Private Dams: The Hell's Canyon High Dam Controversy by Fiege, Mark

“…Fiege reviews Public Power, Private Dams: The Hell's Canyon High Dam Controversy by Karl Boyd Brooks and with a foreword by William Cronon…”
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Public Power, Private Dams: The Hell's Canyon High Dam Controversy by EVENDEN, MATTHEW

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