Search Results - "Boyarskikh, U."

Biodegradation of polyhydroxyalkanoates (PHAs) in tropical coastal waters and identification of PHA-degrading bacteria by Volova, T.G., Boyandin, A.N., Vasiliev, A.D., Karpov, V.A., Prudnikova, S.V., Mishukova, O.V., Boyarskikh, U.A., Filipenko, M.L., Rudnev, V.P., Bá Xuân, Bùi, Việt Dũng, Vũ, Gitelson, I.I.

“…Biodegradability patterns of two PHAs: a polymer of 3-hydroxybutyric acid (3-PHB) and a copolymer of 3-hydroxybutyric and 3-hydroxyvaleric acids (3-PHB/3-PHV)…”
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Development of a Cell Line Containing the Chimeric ETV6-NTRK3 Gene. The Search for Mutations of the Tyrosine Kinase Chimeric Domain That Cause Resistance to Larotrectinib by Boyarskikh, U. A., Savostyanova, T. A., Oscorbin, I. P., Filipenko, M. L.

“…The development, registration, and further use of entrectinib and larotrectinib for the treatment of tumors resulting from oncogenic stimulation of chimeric…”
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Identification of Chimeric NTRK3 Genes in Papillary Thyroid Cancer Cells by Analyzing the Imbalance of the Expression of 5’ and 3’ mRNA Fragments by Oskorbin, I. P., Ivanov, A. A., Smertina, M. A., Demidova, I. A., Boyarskikh, U. A., Kechin, A. A., Bakharev, S. Yu, Samuilenkova, O. V., Vihlyanov, I. V., Kushlinskii, N. E., Filipenko, M. L.

“…The standard for detecting chimeric genes of neurotrophic receptor tyrosine kinases ( NTRK ) is next generation sequencing (NGS). However, this analysis is…”
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Differences in Transcriptomic Profiles of Brain and Thyroid Tumors with NTRK Gene Rearrangement by Kechin, A. A., Koryukov, M. A., Smertina, M. A., Borobova, V. S., Oscorbin, I. P., Ivanov, A. A., Bakharev, S. Yu, Boyarskikh, U. A., Kushlinskii, N. E., Filipenko, M. L.

“…For tumors with chimeric NTRK genes, entrectinib and larotrectinib can be prescribed regardless of tumor localization. We compared changes in the…”
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The Level of LINE-1 mRNA Is Increased in Extracellular Circulating Plasma RNA in Patients with Colorectal Cancer by Filipenko, M. L., Boyarskikh, U. A., Leskov, L. S., Subbotina, K. V., Khrapov, E. A., Sokolov, A. V., Stilidi, I. S., Kushlinskii, N. E.

“…We performed a comparative quantitative analysis of LINE-1 mRNA levels in extracellular total plasma RNA in patients with colon cancer and practically healthy…”
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Prediction of EVT6-NTRK3-Dependent Papillary Thyroid Cancer Using Minor Expression Profile by Kechin, A. A., Ivanov, A. A., Kel, A. E., Kalmykov, A. S., Oskorbin, I. P., Boyarskikh, U. A., Kharpov, E. A., Bakharev, S. Yu, Oskina, N. A., Samuilenkova, O. V., Vikhlyanov, I. V., Kushlinskii, N. E., Filipenko, M. L.

“…Solid tumors resulting from oncogenic stimulation of neurotrophin receptors (TRK) by chimeric proteins are a group of rare tumors of various localization that…”
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Development of a Test System to Detect the Omicron Variant of SARS-CoV-2 and the Frequency of Its Detection in Patients by Filipenko, M. L., Oskorbin, I. P., Shamovskaya, D. V., Kharpov, E. A., Stepanov, A. A., Romanov, V. V., Kuznetsov, V. V., Boyarskikh, U. A., Kechin, A. A., Pechkovsky, E. V., Krivoruchko, A. B., Ivanov, A. M., Kushlinskii, N. E., Vlasov, V. V.

“…We developed a new test system to detect the omicron variant of SARS-CoV-2 using allele-specific reverse transcription PCR and estimated the frequency of its…”
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DNA-Binding Domain of DNA Ligase from the Thermophilic Archaeon Pyrococcus abyssi: Improving Long-Range PCR and Neutralization of Heparin’s Inhibitory Effect by Oscorbin, Igor P, Boyarskikh, U. A, Zakabunin, A. I, Khrapov, E. A, Filipenko, M. L

“…The DNA-binding domain of the DNA ligase from Pyrococcus abyssi (PabDBD) was mapped and cloned into two expression vectors. The resulting 6X His-tagged…”
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Dendritic Cells Transfected with a DNA Construct Encoding Tumour‐associated Antigen Epitopes Induce a Cytotoxic Immune Response Against Autologous Tumour Cells in a Culture of Mononuclear Cells from Colorectal Cancer Patients by Kulikova, E. V., Kurilin, V. V., Shevchenko, J. A., Obleukhova, I. A., Khrapov, E. A., Boyarskikh, U. A., Filipenko, M. L., Shorokhov, R. V., Yakushenko, V. K., Sokolov, A. V., Sennikov, S. V.

“…Significant effort has been devoted to developing effective cancer vaccines based on dendritic cells (DCs) loaded with various tumour antigens, including DNA…”
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Loss of Heterozygosity in BRCA1 and BRCA2 Genes in Patients with Ovarian Cancer and Probability of Its Use for Clinical Classification of Variations by Kechin, A. A., Boyarskikh, U. A., Ermolenko, N. A., Tyulyandina, A. S., Lazareva, D. G., Avdalyan, A. M., Tyulyandin, S. A., Kushlinskii, N. E., Filipenko, M. L.

“…Changes (or variants) in BRCA1 and BRCA2 gene sequences can have different lengths and clinical significance: from single nucleotide variants (SNV) and short…”
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One-phase phenol-free method for microRNA isolation from blood plasma by Shirshova, A.N., Shamovskaya, D.A., Boyarskikh, U.A., Kushlinskii, N.E., Filipenko, M.L.

“…MicroRNA extraction is an essential procedure when discovering MicroRNA-based biomarkers and approaches. Here we describe a new method for microRNA isolation…”
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The prognostic value of circulating in blood tumor DNA as a marker of minimal residual disease in stage I–III colorectal cancer by Polyanskaya, E. M., Fedyanin, M. Yu, Boyarskikh, U. A., Kechin, A. A., Moroz, E. A., Khrapov, E. A., Oskorobin, I. P., Shamovskaya, D. V., Aliev, V. A., Mammadli, Z. Z., Tryakin, A. A., Filipenko, M. L., Tyulendin, S. A.

“…Introduction. Studies on non-metastatic colorectal cancer have demonstrated the prognostic role of circulating tumor (ctDNA) after surgery, and the ability to…”
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Effect of point substitutions in the MnSOD, GPX1, and GSTP1 genes on the risk of familial and sporadic breast cancers in residents of Altai Krai by Ermolenko, N. A, Boyarskikh, U. A, Sushko, A. G, Voronina, E. N, Selezneva, I. A, Sinkina, T. V, Lazarev, A. F, Petrova, V. D, Filipenko, M. L

“…The frequencies of the polymorphic gene variants MnSOD Ala₉Val, GPX1 Pro₁₉₈Leu, and GSTP1 Ile₁₀₅Val were estimated in female residents of Altai krai with…”
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Magnetofection of Human Somatic Cells with Magnetite and Cobalt Ferrospinel Nanoparticles by Sukoyan, M. A., Khrapov, E. A., Voronina, E. N., Boyarskikh, U. A., Gubanov, A. I., Itin, V. I., Magaeva, A. A., Nayden, E. P., Terekhova, O. G., Filipenko, M. L.

“…Superparamagnetic nanoparticles varying by their chemical composition and synthesis method were used to transfer DNA into somatic cells under the infl uence of…”
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Association of chromosome 8q24 variants with prostate cancer risk in the Siberian region of Russia and meta-analysis by Os’kina, N. A., Boyarskikh, U. A., Lazarev, A. F., Petrova, V. D., Ganov, D. I., Tonacheva, O. G., Lifshits, G. I., Filipenko, M. L.

“…Compelling evidence demonstrates the importance of chromosome 8q24 as a locus of susceptibility to prostate cancer. In this work, the association of common…”
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Associations of Polymorphic Variant of MnSOD Gene with Breast Cancer in Residents of the Altai Region by Kostrykina, N. A, Pechkovskiy, E. A, Boyarskikh, U. A, Sushko, A. G, Voronina, E. N, Lazarev, A. F, Petrova, V. D, Zarubina, N. A, Selezneva, I. A, Sinkina, T. V, Terekhova, S. A, Filipenko, M. L

“…The incidence of MnSOD genotypes in residents of the Altai Region suffering from breast cancer and individuals without a history of cancer corresponded to the…”
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Prediction of nonsmall cell lung cancer sensitivity to cisplastin and paclitaxel based on marker gene expression by Boyarskikh, U. A., Kondrakhin, Yu. V., Yevshin, I. S., Sharipov, R. N., Komelkov, A. V., Musatkina, E. A., Tchevkina, E. M., Sukoyan, M. A., Kolpakov, F. A., Kashkin, K. N., Filipenko, M. L.

“…The goal of the present study was to define gene expression signatures that predict a chemosensitivity of nonsmall cell lung cancer (NSCLC) to cisplatin and…”
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P-279 Clinical utility of circulating tumor DNA in resectable and advanced pancreatic cancer by Popova, A., Fedyanin, M., Pokataev, I., Shamovskaya, D., Kudashkin, N., Boyarskikh, U., Kechin, A., Oscorbin, I., Moroz, E., Trigolosov, A., Filipenko, M., Podluzhnyi, D., Tjulandin, S.

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137P Clinical utility of circulating tumour DNA (ctDNA) in resectable gastric cancer (GC) by Fedyanin, M., Ignatova, E., Boyarskikh, U., Polyanskaya, E., Kechin, A., Osccorobin, I., Shamovskaya, D., Popova, A., Trigolosov, A., Nikulin, M., Nered, S., Kalinin, A., Stilidi, I., Moroz, E., Filipenko, M., Tjulandin, S.

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96P Validation for clinical use of NGS-based assay to detect circulating tumor DNA (ctDNA) in patients (pts) with various types of cancer by Fedyanin, M., Boyarskikh, U., Kechin, A., Polyanskaya, E., Aliev, V., Polyakov, A., Kudashkin, N., Arzumanyan, A., Gordeeva, O.O., Bagrova, S., Tikhonovskaya, M., Trigolosov, A., Denchik, D., Nikulin, M., Nered, S., Moroz, E., Chekini, A., Filipenko, M., Tjulandin, S.

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